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Mutational analysis of human T-cell leukemia virus type 2 Tax.
scientific article published in November 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Mutational analysis of human T-cell leukemia virus type 2 Tax
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
leukemia
1 reference
based on heuristic
inferred from title
mutational analysis
1 reference
based on heuristic
inferred from title
T-cell leukemia
1 reference
based on heuristic
inferred from title
author name string
T M Ross
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
A C Minella
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Z Y Fang
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
S M Pettiford
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
P L Green
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 November 1997
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
71
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
8912-8917
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Localization of human T-cell leukemia virus type 1 tax to subnuclear compartments that overlap with interchromatin speckles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Genetic characterization of transactivation of the human T-cell leukemia virus type 1 promoter: Binding of Tax to Tax-responsive element 1 is mediated by the cyclic AMP-responsive members of the CREB/ATF family of transcription factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
HTLV-I and HTLV-II Tax: differences in induction of micronuclei in cells and transcriptional activation of viral LTRs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Differential expression of Rel family members in human T-cell leukemia virus type I-infected cells: transcriptional activation of c-rel by Tax protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Quantitative studies of the effect of HTLV-I Tax protein on CREB protein--DNA binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Human T-cell leukemia virus type II nucleotide sequences between env and the last exon of tax/rex are not required for viral replication or cellular transformation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Definition of a minimal activation domain in human T-cell leukemia virus type I Tax
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Activation of NF-kappa B/Rel by Tax involves degradation of I kappa B alpha and is blocked by a proteasome inhibitor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Chimeric proteins composed of Jun and CREB define domains required for interaction with the human T-cell leukemia virus type 1 Tax protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Structure of 3′ Terminal Region of Type II Human T Lymphotropic Virus: Evidence for New Coding Region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Human adult T-cell leukemia virus: complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Identification of the Putative Transforming Protein of the Human T-Cell Leukemia Viruses HTLV-I and HTLV-II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Antigens Encoded by the 3′-Terminal Region of Human T-Cell Leukemia Virus: Evidence for a Functional Gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Direct evidence that p40x of human T-cell leukemia virus type I is a trans-acting transcriptional activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
Functional relation between HTLV-II x and adenovirus E1A proteins in transcriptional activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
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11 July 2018
The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Identification of a cis-regulatory element involved in accumulation of human T-cell leukemia virus type II genomic mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
In vitro mutagenesis of the human T-cell leukemia virus types I and II tax genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
The internal methionine codons of human T-cell leukemia virus type II rex gene are not required for p24rex production or virus replication and transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Induction of nuclear NF-kappa B DNA binding activity after exposure of lymphoid cells to soluble tax1 protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Induction of the HTLV-I LTR by Jun occurs through the Tax-responsive 21-bp elements
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-1 Tax protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Tax responsiveness of the GM-CSF promoter is mediated by mitogen-inducible sequences other than kappa B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
NF-κB activity in T cells stably expressing the Tax protein of human T cell lymphotropic virus type I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Phosphorylation regulates RNA binding by the human T-cell leukemia virus Rex protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
HTLV-I Tax is a zinc-binding protein: role of zinc in Tax structure and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Empirical Predictions of Protein Conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Characterization of EBV-genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192364
retrieved
11 July 2018
Identifiers
PMC publication ID
192364
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed publication ID
9343258
1 reference
stated in
Europe PubMed Central
PMC publication ID
192364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9343258%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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