(Q35901021)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Identification and characterization of anesthetic targets by mouse molecular genetics approaches (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Elif Engin

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Bernd Antkowiak

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Uwe Rudolph

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

21 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

Canadian Journal of Anaesthesia

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

58

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

178-190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12630-010-9414-1

18 January 2020

exact match

0 references

cites work

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27 July 2018

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Volatile anesthetic effects on midbrain-elicited locomotion suggest that the locomotor network in the ventral spinal cord is the primary site for immobility

27 July 2018

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27 July 2018

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Forebrain and midbrain distribution of major benzodiazepine-sensitive GABAA receptor subunits in the adult C57 mouse as assessed with in situ hybridization

27 July 2018

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Neurons in the ventral spinal cord are more depressed by isoflurane, halothane, and propofol than are neurons in the dorsal spinal cord

27 July 2018

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A GABAergic system in airway epithelium is essential for mucus overproduction in asthma

27 July 2018

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Mapping the contribution of beta3-containing GABAA receptors to volatile and intravenous general anesthetic actions

27 July 2018

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An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice

27 July 2018

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Distinct molecular targets for the central respiratory and cardiac actions of the general anesthetics etomidate and propofol

27 July 2018

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The incidence of awareness during anesthesia: a multicenter United States study

27 July 2018

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Molecular and neuronal substrates for general anaesthetics

27 July 2018

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TREK-1, a K+ channel involved in neuroprotection and general anesthesia

27 July 2018

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Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors

27 July 2018

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Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Blockade of glutamate receptors and barbiturate anesthesia: increased sensitivity to pentobarbital-induced anesthesia despite reduced inhibition of AMPA receptors in GluR2 null mutant mice

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

27 July 2018

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Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor

27 July 2018

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Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.

27 July 2018

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Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes.

27 July 2018

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Structure and function of the NMDA receptor channel

27 July 2018

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Anesthetic potency (MAC) is independent of forebrain structures in the rat.

27 July 2018

1 reference

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The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

27 July 2018

1 reference

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The comparative effects of methohexital, propofol, and etomidate for electroconvulsive therapy

27 July 2018

1 reference

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Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain

27 July 2018

1 reference

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Organotypic monolayer cultures of nervous tissue.

27 July 2018

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Five subtypes of type A gamma-aminobutyric acid receptors identified in neurons by double and triple immunofluorescence staining with subunit-specific antibodies

27 July 2018

1 reference

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Etomidate, a new water-soluble non-barbiturate intravenous induction agent

27 July 2018

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27 July 2018

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Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

21 January 2018

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GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.

21 January 2018

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Cortical glutamatergic neurons mediate the motor sedative action of diazepam.

21 January 2018

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Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance

21 January 2018

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General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

21 January 2018

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Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.

21 January 2018

1 reference

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Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane.

21 January 2018

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Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation

21 January 2018

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Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade

21 January 2018

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Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane.

21 January 2018

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Major role for tonic GABAA conductances in anesthetic suppression of intrinsic neuronal excitability

21 January 2018

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Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

21 January 2018

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Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane

21 January 2018

1 reference

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Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol.

21 January 2018

1 reference

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The effect of a transmembrane amino acid on etomidate sensitivity of an invertebrate GABA receptor.

21 January 2018

1 reference

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Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue.

21 January 2018

1 reference

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Gamma-aminobutyric acid type A receptor beta 2 subunit mediates the hypothermic effect of etomidate in mice

21 January 2018

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Identification of a molecular target mediating the general anesthetic actions of pentobarbital.

21 January 2018

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Isoflurane-induced surgical tolerance mediated only in part by beta3-containing GABA(A) receptors

21 January 2018

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Subunit arrangement and function in NMDA receptors

21 January 2018

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Chronopharmacological studies of ketamine in normal and NMDA epsilon1 receptor knockout mice

21 January 2018

1 reference

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Effect of N-methyl-D-aspartate receptor epsilon1 subunit gene disruption of the action of general anesthetic drugs in mice

21 January 2018

1 reference

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Blockade of AMPA receptors and volatile anesthetics: reduced anesthetic requirements in GluR2 null mutant mice for loss of the righting reflex and antinociception but not minimum alveolar concentration

21 January 2018

1 reference

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The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

21 January 2018

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TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics.

21 January 2018

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Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABAA receptor-mediated inhibition

21 January 2018

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Organotypic slice cultures: a technique has come of age.

21 January 2018

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GABAergic and glutamatergic axons innervate the axon initial segment and organize GABA(A) receptor clusters of cultured hippocampal pyramidal cells

21 January 2018

1 reference

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Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro

21 January 2018

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Subcellular domain-restricted GABAergic innervation in primary visual cortex in the absence of sensory and thalamic inputs.

21 January 2018

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Determination of diffusion and partition coefficients of propofol in rat brain tissue: implications for studies of drug action in vitro.

21 January 2018

1 reference

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Determination of the EC50 amnesic concentration of etomidate and its diffusion profile in brain tissue: implications for in vitro studies.

21 January 2018

1 reference

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Opposing actions of etomidate on cortical theta oscillations are mediated by different gamma-aminobutyric acid type A receptor subtypes

21 January 2018

1 reference

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Etomidate versus propofol for electroconvulsive therapy in patients with schizophrenia

21 January 2018

1 reference

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Pharmacologic and physiologic influences affecting sensory evoked potentials: implications for perioperative monitoring

21 January 2018

1 reference

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Anesthetic effects on electrophysiologic recordings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

Distinct actions of etomidate and propofol at beta3-containing gamma-aminobutyric acid type A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

The involvement of hypothalamic sleep pathways in general anesthesia: testing the hypothesis using the GABAA receptor beta3N265M knock-in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

Modulation of presynaptic beta3-containing GABAA receptors limits the immobilizing actions of GABAergic anesthetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

Dual actions of volatile anesthetics on GABA(A) IPSCs: dissociation of blocking and prolonging effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

Dual actions of enflurane on postsynaptic currents abolished by the gamma-aminobutyric acid type A receptor beta3(N265M) point mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12630-010-9414-1

Organotypic cultures of spinal cord ventral horn are valuable tools for investigating immobility-related mechanisms in vitro

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330822

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

24 September 2018

1 reference

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General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330822

Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.

24 September 2018

1 reference

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Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

24 September 2018

1 reference

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AMPA receptors: molecular and functional diversity.

24 September 2018

1 reference

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Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330822

Exaggerated anesthetic requirements in the preferentially anesthetized brain.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330822

Distribution of immunoreactivity for the beta 2 and beta 3 subunits of the GABAA receptor in the mammalian spinal cord

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21174184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[The GABA(A) receptor family: possibilities for the development of better anesthetics]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21174184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Awareness during anesthesia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21174184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12630-010-9414-1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21174184%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference