(Q35903979)

English

Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment

scientific article published on 9 May 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Dedra H Fagan

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Ryan R Uselman

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Deepali Sachdev

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Douglas Yee

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

9 May 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

72

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

3372-3380

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

The IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

The proliferating role of insulin and insulin-like growth factors in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Insulin and insulin-like growth factor signalling in neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Crosstalk between IGF1R and estrogen receptor signaling in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Targeting insulin and insulin-like growth factor signalling in oncology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

The IGF-I/IGF-I receptor pathway: Implications in the Pathophysiology of Thyroid Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

AKT activation up-regulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Basic guide to the mechanisms of antiestrogen action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Estrogen induces insulin-like growth factor-I expression in the rat uterus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

11 July 2018

Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

24 September 2018

Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

24 September 2018

A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

24 September 2018

Safe and effective method for chronic 17beta-estradiol administration to mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

24 September 2018

Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4520534

24 September 2018

Mechanisms of 4-hydroxytamoxifen anti-growth factor activity in breast cancer cells: alterations of growth factor receptor binding sites and tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of insulin-like growth factor-II (IGF-II) by human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of Insulin-Like Growth Factor Signaling in Human Breast Cancer: Estrogen Regulation of Insulin Receptor Substrate-1 Expressionin Vitroandin Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional responses and in vivo anti-tumour activity of h7C10: a humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of insulin receptors and IGF-I receptors in cancer and other diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commercial interest waxes for IGF-1 blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22573715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-12-0684

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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