(Q35904386)

11 August 2017

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title

Toll-like receptors in the pathogenesis of human disease (English)

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11 August 2017

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Donald N Cook

1

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11 August 2017

David S Pisetsky

series ordinal

2

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11 August 2017

David A Schwartz

series ordinal

3

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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11 August 2017

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11 August 2017

volume

5

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11 August 2017

issue

10

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11 August 2017

page(s)

975-979

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TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

11 August 2017

cites work

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Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock

21 January 2018

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Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility

21 January 2018

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A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection

21 January 2018

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The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease

21 January 2018

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Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling

21 January 2018

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Pyogenic bacterial infections in humans with IRAK-4 deficiency

21 January 2018

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Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections

21 January 2018

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Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

21 January 2018

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Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells

21 January 2018

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Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients

21 January 2018

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TIRAP mediates endotoxin-induced NF-kappaB activation and apoptosis in endothelial cells

21 January 2018

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Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

21 January 2018

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Inherited disorders of NF-kappaB-mediated immunity in man.

21 January 2018

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Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations

21 January 2018

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X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

21 January 2018

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Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

21 January 2018

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A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency

21 January 2018

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Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.

21 January 2018

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Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events

21 January 2018

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Evidence for infectious agents in cardiovascular disease and atherosclerosis

21 January 2018

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Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway

21 January 2018

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Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

21 January 2018

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Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.

21 January 2018

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Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity

21 January 2018

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Environmental exposure to endotoxin and its relation to asthma in school-age children

21 January 2018

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House dust endotoxin and allergic sensitization in children

21 January 2018

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Polymorphisms in Toll-Like Receptor 4 Are Not Associated with Asthma or Atopy-related Phenotypes

21 January 2018

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TLR4 gene variants modify endotoxin effects on asthma

21 January 2018

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Toll-like receptor 4 polymorphism and severity of atopy in asthmatics

21 January 2018

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Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology.

21 January 2018

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Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

21 January 2018

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Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity

21 January 2018

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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

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21 January 2018

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Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation

21 January 2018

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

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Toll-like Receptor 4 Polymorphisms and Atherogenesis

21 January 2018

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Anti-endotoxin monoclonal antibodies--a second look

21 January 2018

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7 January 2021

Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections

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7 January 2021

Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome

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7 January 2021

A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease

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7 January 2021

Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis

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7 January 2021

Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients

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7 January 2021

Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients

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7 January 2021

Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans

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7 January 2021

Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells

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7 January 2021

Divergence of bacterial lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1

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7 January 2021

Severity of asthma is related to endotoxin in house dust

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7 January 2021

Effect of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects

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7 January 2021

Activation of autoreactive B cells by CpG dsDNA

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7 January 2021

Identifiers

DOI

10.1038/NI1116

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11 August 2017

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