(Q35913099)

11 August 2017

Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity (English)

1 reference

11 August 2017

Caroline A Lee

1

1 reference

11 August 2017

J P Jones

2

1 reference

11 August 2017

Jonathan Katayama

3

1 reference

11 August 2017

Rüdiger Kaspera

4

1 reference

11 August 2017

Ying Jiang

5

1 reference

11 August 2017

Sascha Freiwald

6

1 reference

11 August 2017

Evan Smith

7

1 reference

11 August 2017

Gregory S Walker

8

1 reference

11 August 2017

Rheem A Totah

9

1 reference

11 August 2017

10 February 2012

1 reference

Drug Metabolism and Disposition

11 August 2017

1 reference

11 August 2017

40

1 reference

11 August 2017

5

1 reference

11 August 2017

943-951

1 reference

Cytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growth

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Variability of CYP2J2 expression in human fetal tissues

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

The human intestinal cytochrome P450 "pie".

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Cytochrome P450 pathways of arachidonic acid metabolism.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Identification of novel substrates for human cytochrome P450 2J2.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

In vitro inhibition of human small intestinal and liver microsomal astemizole O-demethylation: different contribution of CYP2J2 in the small intestine and liver

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336800

Identification of amiodarone metabolites in human bile by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry

24 September 2018

1 reference

12 December 2020

In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices

1 reference

12 December 2020

Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations

1 reference

12 December 2020

Expression of cytochrome P450 arachidonic acid epoxygenase 2J2 in human tumor tissues and cell lines

1 reference

12 December 2020

Validation of isolated metabolites from drug metabolism studies as analytical standards by quantitative NMR

1 reference

12 December 2020

Identifiers

DOI

10.1124/DMD.111.043505

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22328583

1 reference