(Q35916800)

English

DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia

scientific article published in August 2004

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia (English)

1 reference

Europe PubMed Central

11 August 2017

DNA methylation

0 references

author name string

Björn Rüter

1

1 reference

Europe PubMed Central

11 August 2017

Pierre W Wijermans

2

1 reference

Europe PubMed Central

11 August 2017

Michael Lübbert

3

1 reference

Europe PubMed Central

11 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2004

1 reference

Europe PubMed Central

11 August 2017

International Journal of Hematology

1 reference

Europe PubMed Central

11 August 2017

80

1 reference

Europe PubMed Central

11 August 2017

128-135

1 reference

Europe PubMed Central

11 August 2017

2

1 reference

Europe PubMed Central

11 August 2017

https://scigraph.springernature.com/pub.10.1532/ijh97.04094

0 references

Continuous infusion of low-dose 5-Aza-2'-deoxycytidine in elderly patients with high-risk myelodysplastic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of X-chromosome inactivation in development in mice and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: a Cancer and Leukemia Group B study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Aza-2'-deoxycytidine as a differentiation inducer in acute myeloid leukaemias and myelodysplastic syndromes of the elderly

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of epigenetic changes in hematological malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between chromatin organization and DNA methylation in determining gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene silencing of the p15/INK4B cell-cycle inhibitor by hypermethylation: an early or later epigenetic alteration in myelodysplastic syndromes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brief report: treatment with azacitidine of patients with end-stage beta-thalassemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of prolonged infusions of the putative differentiating agent sodium phenylbutyrate on myelodysplastic syndromes and acute myeloid leukemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic hypomethylation in human chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG islands in vertebrate genomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of DNA methylation in chronic lymphocytic leukemia patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation levels in acute human leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in DNA methylation: a fundamental aspect of neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation-induced repression--belts, braces, and chromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG islands and genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone methylation in transcriptional control

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gametic imprinting in mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of treatment with 5-azacytidine on the in vivo and in vitro hematopoiesis in patients with myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The evaluation of low-dose cytarabine in the treatment of myelodysplastic syndromes: a phase-III intergroup study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental regulation of myeloid gene expression and demethylation during ex vivo culture of peripheral blood progenitor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypermethylation of gene promoters in hematological neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological approach for optimization of the dose schedule of 5-Aza-2'-deoxycytidine (Decitabine) for the therapy of leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Management of acute myeloid leukemia in elderly patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG-rich islands and the function of DNA methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15481440

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1532/IJH97.04094

1 reference

Europe PubMed Central

11 August 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

11 August 2017

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