(Q35917735)

English

Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes.

scientific article published on 15 March 2012

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22420994%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22420994%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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1

1 reference

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26 January 2020

author name string

Peter S Silverstein

2

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26 January 2020

Dhirendra P Singh

3

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26 January 2020

Anil Kumar

4

1 reference

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26 January 2020

publication date

15 March 2012

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26 January 2020

Journal of Neuroinflammation

1 reference

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26 January 2020

9

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26 January 2020

52

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PMC publication ID

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26 January 2020

15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes

1 reference

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The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway

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The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesis

1 reference

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11 July 2018

Methamphetamine toxicity and its implications during HIV-1 infection.

1 reference

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11 July 2018

HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA

1 reference

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11 July 2018

Astrocytes in the tempest of multiple sclerosis.

1 reference

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11 July 2018

Novel neuroinflammatory targets in the chronically injured spinal cord

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11 July 2018

Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier.

1 reference

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11 July 2018

Huntington's disease and Group I metabotropic glutamate receptors

1 reference

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11 July 2018

Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of metabotropic glutamate receptor 5

1 reference

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11 July 2018

Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions

1 reference

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11 July 2018

Methamphetamine Causes Mitrochondrial Oxidative Damage in Human T Lymphocytes Leading to Functional Impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Group I metabotropic glutamate receptor signalling and its implication in neurological disease

1 reference

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11 July 2018

Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease

1 reference

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11 July 2018

Molecular bases of methamphetamine-induced neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Dopamine-induced behavioral changes and oxidative stress in methamphetamine-induced neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

A role for mGluR5 receptors in intravenous methamphetamine self-administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

The role of oxidative stress, metabolic compromise, and inflammation in neuronal injury produced by amphetamine-related drugs of abuse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Chronic stress enhances methamphetamine-induced extracellular glutamate and excitotoxicity in the rat striatum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Methamphetamine inhibits antigen processing, presentation, and phagocytosis

1 reference

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11 July 2018

Blood-brain barrier: structural components and function under physiologic and pathologic conditions

1 reference

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11 July 2018

Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor- alpha

1 reference

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11 July 2018

Induction of striatal pre- and postsynaptic damage by methamphetamine requires the dopamine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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Changes in cytokines and neurotrophins in Parkinson's disease

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Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning

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11 July 2018

Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine.

1 reference

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11 July 2018

Methamphetamine-induced changes in antioxidant enzymes and lipid peroxidation in copper/zinc-superoxide dismutase transgenic mice

1 reference

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11 July 2018

Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter.

1 reference

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11 July 2018

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

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11 July 2018

NF-kappa B subunit-specific regulation of the interleukin-8 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Potential involvement of the transcription factor NF-kappa B in neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3338363

11 July 2018

Establishment of a line of human fetal glial cells that supports JC virus multiplication

1 reference

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11 July 2018

Methamphetamine-induced expression of interleukin-1 beta mRNA in the rat hypothalamus

1 reference

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11 July 2018

Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin.

1 reference

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1 reference

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24 September 2018

Methamphetamine-induced early increase of IL-6 and TNF-alpha mRNA expression in the mouse brain

1 reference

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24 September 2018

Direct evidence of astrocytic modulation in the development of rewarding effects induced by drugs of abuse

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24 September 2018

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

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24 September 2018

Methamphetamine activates DNA binding of specific redox-responsive transcription factors in mouse brain

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24 September 2018

Methamphetamine induces AP-1 and NF-kappaB binding and transactivation in human brain endothelial cells

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24 September 2018

Protein phosphorylation cascades associated with methamphetamine-induced glial activation

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24 September 2018

Cytokine regulation of interleukin-6 gene expression in astrocytes involves activation of an NF-κ B-like nuclear protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22420994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of MK-801 on methamphetamine-induced depletion of dopaminergic and serotonergic terminals and striatal astrocytic response: an immunohistochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22420994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology of microglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22420994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-9-52

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22420994%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22420994%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22420994%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

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