(Q35930971)

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Substance P Inhibits Hyperosmotic Stress-Induced Apoptosis in Corneal Epithelial Cells through the Mechanism of Akt Activation and Reactive Oxygen Species Scavenging via the Neurokinin-1 Receptor

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Europe PubMed Central

PMC publication ID

11 August 2017

Substance P Inhibits Hyperosmotic Stress-Induced Apoptosis in Corneal Epithelial Cells through the Mechanism of Akt Activation and Reactive Oxygen Species Scavenging via the Neurokinin-1 Receptor (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Lingling Yang

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Wenjie Sui

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Yunqiu Li

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Xia Qi

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Yao Wang

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Qingjun Zhou

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Hua Gao

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

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publication date

22 February 2016

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

e0149865

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

copyright license

Creative Commons Attribution 4.0 International

22 February 2016

1 reference

April 2022 Public Data File from Crossref

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0 references

Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis.

1 reference

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Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptor

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2 October 2017

Tear osmolarity and dry eye symptoms in diabetics.

1 reference

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2 October 2017

Anti-apoptotic effect of caspase inhibitors on H₂O₂-treated HeLa cells through early suppression of its oxidative stress

1 reference

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Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition

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Inflammatory cytokine and osmolarity changes in the tears of dry eye patients treated with topical 1% methylprednisolone

1 reference

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2 October 2017

Decrease in hyperosmotic stress-induced corneal epithelial cell apoptosis by L-carnitine

1 reference

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2 October 2017

Substance P reduces TNF-α-induced apoptosis in human tenocytes through NK-1 receptor stimulation

1 reference

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2 October 2017

Substance P acting via the neurokinin-1 receptor regulates adverse myocardial remodeling in a rat model of hypertension

1 reference

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2 October 2017

Akt-mediated anti-apoptotic effects of substance P in Anti-Fas-induced apoptosis of human tenocytes

1 reference

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2 October 2017

Betaine stabilizes cell volume and protects against apoptosis in human corneal epithelial cells under hyperosmotic stress.

1 reference

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2 October 2017

Hyperosmolarity potentiates toxic effects of benzalkonium chloride on conjunctival epithelial cells in vitro

1 reference

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2 October 2017

Targeting of substance P induces cancer cell death and decreases the steady state of EGFR and Her2.

1 reference

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2 October 2017

Hyperosmotic stress-induced corneal epithelial cell death through activation of Polo-like kinase 3 and c-Jun.

1 reference

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2 October 2017

Relationship between caspase activity and apoptotic markers in human sperm in response to hydrogen peroxide and progesterone

1 reference

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2 October 2017

SP protects cerebellar granule cells against beta-amyloid-induced apoptosis by down-regulation and reduced activity of Kv4 potassium channels

1 reference

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Proinflammatory tachykinins that signal through the neurokinin 1 receptor promote survival of dendritic cells and potent cellular immunity

1 reference

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2 October 2017

Stratified epithelial sheets engineered from a single adult murine corneal/limbal progenitor cell.

1 reference

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2 October 2017

NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2.

1 reference

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2 October 2017

Substance P mediates antiapoptotic responses in human colonocytes by Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762577

2 October 2017

Mechanisms of cell death in oxidative stress

1 reference

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2 October 2017

An unidentified depressor substance in certain tissue extracts

1 reference

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2 October 2017

Using osmolarity to diagnose dry eye: a compartmental hypothesis and review of our assumptions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762577

2 October 2017

The tachykinin peptide family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762577

2 October 2017

Corneal epithelial wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4762577

2 October 2017

Role of reactive oxygen species (ROS) in apoptosis induction

1 reference

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2 October 2017

Substance P: a pioneer amongst neuropeptides

1 reference

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The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

1 reference

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Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis

1 reference

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Mitochondria and apoptosis

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Death receptors: signaling and modulation

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Activation of autophagy via Ca(2+)-dependent AMPK/mTOR pathway in rat notochordal cells is a cellular adaptation under hyperosmotic stress

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Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis

1 reference

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Isolation of a Sialogogic Peptide from Bovine Hypothalamic Tissue and Its Characterization as Substance P

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Eicosapentaenoic acid (EPA) induced apoptosis in HepG2 cells through ROS-Ca(2+)-JNK mitochondrial pathways

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Dry eye and its correlation to diabetes microvascular complications in people with type 2 diabetes mellitus.

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24 September 2018

A link between tear instability and hyperosmolarity in dry eye.

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Caspase 3 activation in human spermatozoa in response to hydrogen peroxide and progesterone

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Reactive oxygen species (ROS) mediates the mitochondrial-dependent apoptosis induced by transforming growth factor (beta) in fetal hepatocytes.

1 reference

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24 September 2018

Hyperosmolarity-mediated mitochondrial dysfunction requires Transglutaminase-2 in human Corneal epithelial cells

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26901348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tear osmolarity--a new gold standard?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26901348

12 December 2020

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inferred from PubMed ID database lookup

Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/26901348

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inferred from PubMed ID database lookup

Tear fluid osmolarity as a potential marker of hydration status

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https://pubmed.ncbi.nlm.nih.gov/26901348

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Comparison of tear-film osmolarity in different types of contact lenses

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inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0149865

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

2016PLoSO..1149865Y

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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