(Q35933720)

11 August 2017

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title

Prevention of type 2 diabetes mellitus through inhibition of the Renin-Angiotensin system (English)

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11 August 2017

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André J Scheen

1

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11 August 2017

1 January 2004

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11 August 2017

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11 August 2017

64

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11 August 2017

2537-2565

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11 August 2017

22

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https://scigraph.springernature.com/pub.10.2165/00003495-200464220-00004

11 August 2017

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Lisinopril administration improves insulin action in aged patients with hypertension.

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Relation of pressor responsiveness to angiotensin II and insulin resistance in hypertension

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The insertion/deletion polymorphism of the ACE gene is related to insulin sensitivity in overweight women

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Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients

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Metabolic effects of long-term angiotensin-converting enzyme inhibition with fosinopril in patients with essential hypertension: relationship to angiotensin-converting enzyme inhibition

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Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension

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Opposing effects of angiotensin II on muscle and renal blood flow under euglycemic conditions.

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Association of the ACE gene I/D polymorphism with insulin sensitivity depends on the presence of additional macroangiopathic risk factors

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12 December 2020

Losartan mediated improvement in insulin action is mainly due to an increase in non-oxidative glucose metabolism and blood flow in insulin-resistant hypertensive patients

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12 December 2020

Prevention of the Glucose Intolerance of Thiazide Diuretics by Maintenance of Body Potassium

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Induction of insulin resistance by beta-blockade but not ACE-inhibition: long-term treatment with atenolol or trandolapril.

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12 December 2020

Risk factors for developing non-insulin dependent diabetes: a 10 year follow up of men in Uppsala

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12 December 2020

Insertion/deletion polymorphism of the ACE gene is associated with type 2 diabetes

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12 December 2020

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12 December 2020

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12 December 2020

Angiotensin II induces insulin resistance independent of changes in interstitial insulin

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12 December 2020

Modulation of metabolic control by angiotensin converting enzyme (ACE) inhibition

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12 December 2020

Angiotensin-Converting Enzyme Inhibitors and Insulin Sensitivity: Metabolic Effects in Hypertension, Diabetes, and Heart Failure

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12 December 2020

Microalbuminuria precedes the development of NIDDM

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12 December 2020

A comparison of the hypotensive and hypoglycaemic actions of an angiotensin converting enzyme inhibitor, an AT1a antagonist and troglitazone

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12 December 2020

Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study.

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12 December 2020

The effects of valsartan on insulin sensitivity in patients with primary hypertension

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12 December 2020

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12 December 2020

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Angiotensin I converting enzyme gene polymorphism and insulin resistance in patients with hypertension

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12 December 2020

Effects of the angiotensin converting enzyme inhibitor temocapril on insulin sensitivity and its effects on renal sodium handling and the pressor system in essential hypertensive patients.

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12 December 2020

Angiotensin II affects basal, pulsatile, and glucose-stimulated insulin secretion in humans.

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12 December 2020

Insulin resistance and hypertension

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12 December 2020

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12 December 2020

Angiotensinogen gene polymorphism is associated with insulin resistance in nondiabetic men with or without coronary heart disease.

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12 December 2020

Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project

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12 December 2020

Effect of captopril on glucose concentration. Possible role of augmented postprandial forearm blood flow.

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12 December 2020

Health care and health status and outcomes for patients with type 2 diabetes

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12 December 2020

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12 December 2020

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12 December 2020

Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme

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12 December 2020

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12 December 2020

Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study

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12 December 2020

The I/D polymorphism of angiotensin-converting enzyme gene but not the angiotensinogen gene is associated with insulin response to oral glucose in Japanese

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12 December 2020

Tissue renin-angiotensin system: its expression, localization, regulation and potential role in the pancreas

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12 December 2020

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12 December 2020

Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease

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12 December 2020

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12 December 2020

Insulin-resistant lipolysis in abdominally obese hypertensive individuals. Role of the renin-angiotensin system

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12 December 2020

The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?

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12 December 2020

Relationship between angiotensin-converting enzyme gene polymorphism and insulin resistance in never-treated hypertensive patients

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12 December 2020

A new dimension in hypertension: role of insulin resistance

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12 December 2020

Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group

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12 December 2020

Angiotensin blockade prevents type 2 diabetes by formation of fat cells

1 reference

12 December 2020

Insulin resistance, glucose intolerance and hyperinsulinemia in patients with hypertension

1 reference

12 December 2020

Insulin resistance and hyperinsulinemia in patients with chronic congestive heart failure.

1 reference

12 December 2020

Effects of losartan on insulin sensitivity in hypertensive subjects

1 reference

12 December 2020

Improved insulin action and glycemic control after long-term angiotensin-converting enzyme inhibition in subjects with arterial hypertension and type II diabetes.

1 reference

12 December 2020

A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension

1 reference

12 December 2020

ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients

1 reference

12 December 2020

Crosstalk between insulin and angiotensin II signalling systems

1 reference

12 December 2020

Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial

1 reference

12 December 2020

Hypertension and associated metabolic abnormalities--the role of insulin resistance and the sympathoadrenal system

1 reference

12 December 2020

The renin-angiotensin system and the long-term complications of diabetes: pathophysiological and therapeutic considerations.

1 reference

12 December 2020

Electrolyte changes and metabolic effects of lisinopril/bendrofluazide treatment. Results from a randomized, double-blind study with parallel groups

1 reference

12 December 2020

Angiotensin-converting enzyme (ACE) inhibition. Therapeutic option for diabetic hypertensive patients

1 reference

12 December 2020

Interactions of captopril and verapamil on glucose tolerance and insulin action in an animal model of insulin resistance.

1 reference

12 December 2020

ACE-inhibition increases hepatic and extrahepatic sensitivity to insulin in patients with type 2 (non-insulin-dependent) diabetes mellitus and arterial hypertension

1 reference

12 December 2020

Insulin sensitivity in obese hypertensive dyslipidemic patients treated with enalapril or atenolol

1 reference

12 December 2020

Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians

1 reference

12 December 2020

The effect of angiotensin II receptor blockade on insulin sensitivity and sympathetic nervous system activity in primary hypertension.

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12 December 2020

Improved insulin response and action by chronic magnesium administration in aged NIDDM subjects

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12 December 2020

Effect of angiotensin converting enzyme inhibitor (lisinopril) on insulin sensitivity and sodium transport in mild hypertension.

1 reference

12 December 2020

Hypertension in Diabetes Study (HDS): I. Prevalence of hypertension in newly presenting type 2 diabetic patients and the association with risk factors for cardiovascular and diabetic complications

1 reference

12 December 2020

Genetic variability in the renin-angiotensin system: prevalence of alleles and genotypes

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12 December 2020

Effect of experimental potassium deficiency on glucose and insulin metabolism

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12 December 2020

Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity

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12 December 2020

Effects of Antihypertensive Treatment on Insulin Sensitivity With Special Reference to ACE Inhibitors

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12 December 2020

Deletion polymorphism in the gene for angiotensin converting enzyme is associated with elevated fasting blood glucose levels.

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12 December 2020

Ramipril and the development of diabetes.

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12 December 2020

Effect of captopril, losartan, and bradykinin on early steps of insulin action

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12 December 2020

Hypertension, the Potassium Ion and Impaired Carbohydrate Tolerance

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12 December 2020

Trandolapril does not improve insulin sensitivity in patients with hypertension and type 2 diabetes: a double-blind, placebo-controlled crossover trial

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12 December 2020

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

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12 December 2020

Antihypertensive drug therapy and the initiation of treatment for diabetes mellitus

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12 December 2020

Hyperinsulinemia and elevated blood pressure: cause, confounder, or coincidence?

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12 December 2020

Magnesium and glucose homeostasis

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12 December 2020

Management of type 2 diabetes mellitus and cardiovascular risk: lessons from intervention trials

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12 December 2020

Enalapril reduces the incidence of diabetes in patients with chronic heart failure: insight from the Studies Of Left Ventricular Dysfunction (SOLVD).

1 reference

12 December 2020

Hyperinsulinemia. A link between hypertension obesity and glucose intolerance

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12 December 2020

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels

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12 December 2020

Pathophysiological implications of insulin resistance on vascular endothelial function.

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12 December 2020

Circulating catecholamines and metabolic effects of captopril in NIDDM patients

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12 December 2020

Adiponectin: more than just another fat cell hormone?

1 reference

12 December 2020

Quinapril treatment enhances vascular sensitivity to insulin

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12 December 2020

CAPPP trial. Captopril Prevention Project

1 reference

12 December 2020

Effects of inhibition of the renin-angiotensin system on the cardiovascular actions of insulin

1 reference

12 December 2020

Potential role of bradykinin in forearm muscle metabolism in humans

1 reference

12 December 2020

The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance

1 reference

12 December 2020

A possible link between endothelial dysfunction and insulin resistance in hypertension. A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.

1 reference

12 December 2020

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

1 reference

12 December 2020

ACE inhibition and glucose transport in insulinresistant muscle: roles of bradykinin and nitric oxide.

1 reference

12 December 2020

Modulation of insulin receptor signaling. Potential mechanisms of a cross talk between bradykinin and the insulin receptor

1 reference

12 December 2020

Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM.

1 reference

12 December 2020

Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving vascular resistance in the Zucker fatty rat.

1 reference

12 December 2020

Effects of calcium antagonists on glucose homeostasis and serum lipids in non-diabetic and diabetic subjects: a review.

1 reference

12 December 2020

Insulin resistance in essential hypertension

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12 December 2020

Role of the B(2) receptor of bradykinin in insulin sensitivity

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12 December 2020

Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects.

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12 December 2020

Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats

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12 December 2020

Captopril and insulin sensitivity

1 reference

12 December 2020

Antihypertensive therapy and the risk of type 2 diabetes mellitus

1 reference

12 December 2020

Association between antihypertensive drug use and hypoglycemia: a case-control study of diabetic users of insulin or sulfonylureas

1 reference

12 December 2020

Regression of left ventricular mass with captopril and metoprolol, and the effects on glucose and lipid metabolism

1 reference

12 December 2020

Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure.

1 reference

12 December 2020

PPAR(gamma) and glucose homeostasis

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12 December 2020

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

1 reference

12 December 2020

Insulin-sensitizing effects of telmisartan: implications for treating insulin-resistant hypertension and cardiovascular disease

1 reference

12 December 2020

Effects of angiotensin-converting enzyme inhibitors on glucose and lipid metabolism in essential hypertension

1 reference

12 December 2020

Incidence of NIDDM and impaired glucose tolerance in hypertensive subjects. The San Antonio Heart Study.

1 reference

12 December 2020

Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor

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12 December 2020

From the HOPE to the ONTARGET and the TRANSCEND studies: challenges in improving prognosis

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12 December 2020

Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients

1 reference

12 December 2020

Genetic variation in the renin-angiotensin system and abdominal adiposity in men: the Olivetti Prospective Heart Study

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12 December 2020

Improving the action of insulin.

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12 December 2020

Banting lecture 1988. Role of insulin resistance in human disease

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12 December 2020

Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation

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12 December 2020

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<SUBTITLE>The JNC 7 Report</SUBTITLE>

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12 December 2020

The role of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists in the management of diabetic complications

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12 December 2020

Do antihypertensive drugs precipitate diabetes?

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12 December 2020

The hemodynamic link between insulin resistance and hypertension

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12 December 2020

Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension

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12 December 2020

Antihypertensive therapy and incidence of type 2 diabetes: a systematic review

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12 December 2020

Is There a Role for ??-Glucosidase Inhibitors in the Prevention of Type 2 Diabetes Mellitus?

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12 December 2020

Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Blood Pressure Lowering Treatment Trialists' Collaboration

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12 December 2020

Clinical review 79: Angiotensin II: an insulin-sensitizing vasoactive hormone?

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12 December 2020

Physiology and pathophysiology of the adipose tissue renin-angiotensin system

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12 December 2020

Angiotensin I converting enzyme gene polymorphism and insulin resistance in patients with angina pectoris

1 reference

12 December 2020

Effects of chronic angiotensin converting enzyme inhibition on glucose tolerance and insulin sensitivity in essential hypertension.

1 reference

12 December 2020

Major Factors in the Development of Diabetes Mellitus in 10,000 Men

1 reference

12 December 2020

Effect of an angiotensin II receptor antagonist, candesartan, on insulin resistance and pressor mechanisms in essential hypertension.

1 reference

12 December 2020

Inhibition of angiotensin type 1 receptor prevents decline of glucose transporter (GLUT4) in diabetic rat heart

1 reference

12 December 2020

Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study

1 reference

12 December 2020

Metabolic effects of doxazosin and enalapril in hypertriglyceridemic, hypertensive men. Relationship to changes in skeletal muscle blood flow.

1 reference

12 December 2020

The effects of ramipril on glucose tolerance, insulin secretion, and insulin sensitivity in patients with hypertension

1 reference

12 December 2020

The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group

1 reference

12 December 2020

Captopril does not improve insulin action in essential hypertension: a double-blind placebo-controlled study.

1 reference

12 December 2020

10.2165/00003495-200464220-00004

Identifiers

DOI

1 reference

PubMed ID

15516153

Dimensions Publication ID

11 August 2017

0 references

1 reference

PubMed ID

15516153