(Q35940952)

11 August 2017

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title

Advances in the production of human therapeutic proteins in yeasts and filamentous fungi (English)

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11 August 2017

Tillman U Gerngross

1

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PubMed ID

15529166

11 August 2017

language of work or name

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1 November 2004

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11 August 2017

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11 August 2017

22

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11 August 2017

11

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11 August 2017

1409-1414

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https://scigraph.springernature.com/pub.10.1038/nbt1028

11 August 2017

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cites work

Biopharmaceutical benchmarks--2003

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7 January 2021

Filamentous fungi as cell factories for heterologous protein production

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7 January 2021

The role of carbohydrate in the assembly and function of polymeric IgG.

1 reference

7 January 2021

Therapeutic delivery of proteins to macrophages: implications for treatment of Gaucher's disease

1 reference

7 January 2021

Enzyme therapy in type 1 Gaucher disease: comparative efficacy of mannose-terminated glucocerebrosidase from natural and recombinant sources

1 reference

7 January 2021

Genetic engineering of recombinant glycoproteins and the glycosylation pathway in mammalian host cells

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7 January 2021

N-glycosylation/deglycosylation as a mechanism for the post-translational modification/remodification of proteins

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7 January 2021

Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cells

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7 January 2021

Relationships between the N‐glycan structures and biological activities of recombinant human erythropoietins produced using different culture conditions and purification procedures

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7 January 2021

Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.

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7 January 2021

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

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7 January 2021

Enhancing therapeutic glycoprotein production in Chinese hamster ovary cells by metabolic engineering endogenous gene control with antisense DNA and gene targeting

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7 January 2021

Recombinant protein expression in Pichia pastoris

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7 January 2021

Expression and characterization of recombinant human antithrombin III in Pichia pastoris

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7 January 2021

Characterization of humanized antibodies secreted by Aspergillus niger

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7 January 2021

High-level secretory expression of immunologically active intact antibody from the yeast Pichia pastoris

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7 January 2021

In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides--evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei.

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7 January 2021

Assembly of asparagine-linked oligosaccharides

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7 January 2021

Control of glycoprotein synthesis. The use of oligosaccharide substrates and HPLC to study the sequential pathway for N-acetylglucosaminyltransferases I, II, III, IV, V, and VI in the biosynthesis of highly branched N-glycans by hen oviduct membrane

1 reference

7 January 2021

Biochemistry, molecular biology, and genetics of the oligosaccharyltransferase.

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7 January 2021

Overview of N- and O-linked oligosaccharide structures found in various yeast species

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7 January 2021

Insertion into Aspergillus nidulans of functional UDP-GlcNAc: alpha 3-D- mannoside beta-1,2-N-acetylglucosaminyl-transferase I, the enzyme catalysing the first committed step from oligomannose to hybrid and complex N-glycans

1 reference

7 January 2021

Production of human compatible high mannose-type (Man5GlcNAc2) sugar chains in Saccharomyces cerevisiae

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7 January 2021

Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris

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7 January 2021

In vivo synthesis of mammalian-like, hybrid-type N-glycans in Pichia pastoris

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7 January 2021

Production of complex human glycoproteins in yeast

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7 January 2021

Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose

1 reference

7 January 2021

Identifiers

DOI

10.1038/NBT1028

1 reference

PubMed ID

15529166

Dimensions Publication ID

11 August 2017

0 references

1 reference

PubMed ID

15529166