Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35941244)
Watch
English
Saquinavir inhibits the malaria parasite's chloroquine resistance transporter.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
title
Saquinavir inhibits the malaria parasite's chloroquine resistance transporter
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
main subject
malaria
0 references
chloroquine
0 references
saquinavir
1 reference
based on heuristic
inferred from title
author
Rowena Martin
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Kiaran Kirk
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
James S McCarthy
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Tina S Skinner-Adams
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
author name string
Alice S Butterworth
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Donald L Gardiner
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
language of work or name
English
0 references
publication date
21 February 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
number of pages
7
1 reference
based on heuristic
inferred from page(s)
published in
Antimicrobial Agents and Chemotherapy
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
volume
56
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
page(s)
2283-2289
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
cites work
In vitro activity of antiretroviral drugs against Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
4-aminoquinolines active against chloroquine-resistant Plasmodium falciparum: basis of antiparasite activity and quantitative structure-activity relationship analyses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Differential drug efflux or accumulation does not explain variation in the chloroquine response of Plasmodium falciparum strains expressing the same isoform of mutant PfCRT.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Similar efficacy and tolerability of double-dose chloroquine and artemether-lumefantrine for treatment of Plasmodium falciparum infection in Guinea-Bissau: a randomized trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Chloroquine transport via the malaria parasite's chloroquine resistance transporter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Plasmodium falciparum culture: the benefits of shaking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
The global portfolio of new antimalarial medicines under development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Synergy of human immunodeficiency virus protease inhibitors with chloroquine against Plasmodium falciparum in vitro and Plasmodium chabaudi in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Synergistic interactions of the antiretroviral protease inhibitors saquinavir and ritonavir with chloroquine and mefloquine against Plasmodium falciparum in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
The intracellular pharmacology of antiretroviral protease inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Antiretrovirals as antimalarial agents.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Differential diffusions of indinavir and lopinavir in genital secretions of human immunodeficiency virus-infected women
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
A molecular marker for chloroquine-resistant falciparum malaria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Synergistic in vitro antimalarial activity of omeprazole and quinine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Inhibitors of HIV-1 protease: a major success of structure-assisted drug design
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
Human malaria parasites in continuous culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
2 October 2017
The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
Synthesis of new 4-aminoquinolines and quinoline-acridine hybrids as antimalarial agents
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
Antiretroviral protease inhibitors potentiate chloroquine antimalarial activity in malaria parasites by regulating intracellular glutathione metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
Antimalarial activity of sera from subjects taking HIV protease inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
The pH of the digestive vacuole of Plasmodium falciparum is not associated with chloroquine resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
A Method for Testing for Synergy with Any Number of Agents
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
11 July 2018
pH regulation in the intracellular malaria parasite, Plasmodium falciparum. H(+) extrusion via a V-type H(+)-ATPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3346596
retrieved
24 September 2018
pKa determination of verapamil by liquid-liquid partition
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22354298
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22354298
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/AAC.00166-12
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PMC publication ID
3346596
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PubMed publication ID
22354298
1 reference
stated in
Europe PubMed Central
PMC publication ID
3346596
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354298%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit