(Q35952013)

11 August 2017

A point mutation leads to altered product specificity in beta-lactamase catalysis (English)

1 reference

11 August 2017

E R Lewis

1

1 reference

11 August 2017

K M Winterberg

series ordinal

2

1 reference

11 August 2017

A L Fink

series ordinal

3

1 reference

11 August 2017

language of work or name

English

0 references

publication date

1 January 1997

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

1 reference

11 August 2017

94

1 reference

11 August 2017

2

1 reference

11 August 2017

443-447

1 reference

11 August 2017

Tissue sulfhydryl groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Contribution of mutant analysis to the understanding of enzyme catalysis: the case of class A beta-lactamases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

The refined crystallographic structure of a DD-peptidase penicillin-target enzyme at 1.6 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Beta-lactamase of Bacillus licheniformis 749/C at 2 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Beta-lactamase of Bacillus licheniformis 749/C. Refinement at 2 A resolution and analysis of hydration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

The crisis in antibiotic resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Degradation of penicillin G to phenylacetylglycine by D-alanine carboxypeptidase from Bacillus stearothermophilus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Cephalosporin-sensitive penicillin-binding proteins of Staphylococcus aureus and Bacillus subtilis active in the conversion of [14C]penicillin G to [14C]phenylacetylglycine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

The mechanism of action of DD-peptidases: the role of tyrosine-159 in the Streptomyces R61 DD-peptidase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Mechanism of action of DD-peptidases: role of asparagine-161 in the Streptomyces R61 DD-peptidase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Site-directed mutagenesis of .beta.-lactamase leading to accumulation of a catalytic intermediate

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Importance of the two tryptophan residues in the Streptomyces R61 exocellular DD-peptidase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19531

Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Kinetic characterization of the acyl-enzyme mechanism for beta-lactamase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

beta-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Structure-based design of a lysozyme with altered catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Fate of thiazolidine ring during fragmentation of penicillin by exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Streptomyces R61 DD-carboxypeptidase: hydrolysis of X-D-alanyl-D-alanine peptides measured by a fluorometric assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Degradation of penicillin G methyl ester with trifluoroacetic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.94.2.443

Formation of 5,5-dimethyl-delta2-thiazoline-4-carboxylic acid during cleavage of penicillin G by D-alanine carboxypeptidase from Bacillus stearothermophilus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9012802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Site-directed mutants, at position 166, of RTEM-1 beta-lactamase that form a stable acyl-enzyme intermediate with penicillin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9012802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.94.2.443

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

9012802

1 reference