(Q35956765)

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Tamm-Horsfall protein regulates circulating and renal cytokines by affecting glomerular filtration rate and acting as a urinary cytokine trap

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1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Tamm-Horsfall protein regulates circulating and renal cytokines by affecting glomerular filtration rate and acting as a urinary cytokine trap (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Yan Liu

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Tarek M El-Achkar

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Xue-Ru Wu

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

27 March 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

20

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

16365-16378

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lipocalin-2 (24p3/neutrophil gelatinase-associated lipocalin (NGAL)) receptor is expressed in distal nephron and mediates protein endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

The rediscovery of uromodulin (Tamm-Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Organ crosstalk: the role of the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Anti-cytokine therapeutics: history and update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Multiple loci associated with indices of renal function and chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Exploring the full spectrum of macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Cystatin C: current position and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Harmful molecular mechanisms in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Cytokine dysregulation in chronic kidney disease: how can we treat it?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

N-Glycans carried by Tamm-Horsfall glycoprotein have a crucial role in the defense against urinary tract diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tamm-Horsfall protein: a multilayered defence molecule against urinary tract infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Uromodulin storage diseases: clinical aspects and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tamm-Horsfall glycoprotein: biology and clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Cytokine and cytokine receptor pleiotropy and redundancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

The ZP domain is a conserved module for polymerization of extracellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Polarized expression of Tamm-Horsfall protein by renal tubular epithelial cells activates human granulocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Cytokines and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Glomerular ultrafiltration and apical tubular action of IGF-I, TGF-beta, and HGF in nephrotic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Uromodulin and Tamm-Horsfall protein induce human monocytes to secrete TNF and express tissue factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tumor necrosis factor: function, release and clearance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

The renal toxicity of sustained glomerular protein traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Glomerular actions of angiotensin II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Identification of human uromodulin as the Tamm-Horsfall urinary glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

The lectin-like interaction between recombinant tumor necrosis factor and uromodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Human urine-derived inhibitors of interleukin 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Urinary protein electrophoresis profile in normal and hypertensive pregnancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Uromodulin (Tamm-Horsfall glycoprotein/uromucoid) is a phosphatidylinositol-linked membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Tamm-Horsfall protein--uromodulin (1950-1990).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

2 October 2017

Are Tamm-Horsfall protein and uromodulin identical?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

27 July 2018

Decreased urinary concentration of Tamm-Horsfall protein is associated with development of renal failure and cardiovascular death within 20 years in type 1 but not in type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Importance of carbohydrate in the interaction of Tamm-Horsfall protein with complement 1q and inhibition of classical complement activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Variation of high mannose chains of Tamm-Horsfall glycoprotein confers differential binding to type 1-fimbriated Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Renal manifestations of a mutation in the uromodulin (Tamm Horsfall protein) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Analysis of the C-terminal structure of urinary Tamm-Horsfall protein reveals that the release of the glycosyl phosphatidylinositol-anchored counterpart from the kidney occurs by phenylalanine-specific proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

How renal cytokines and growth factors contribute to renal disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Intrarenal handling of recombinant human interleukin-1alpha in rats: mechanism for proximal tubular protein reabsorption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Tamm-Horsfall protein isolated from urine of pregnant and non-pregnant women has similar oligosaccharides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

Rapid determination of glomerular filtration rate by single-bolus inulin: a comparison of estimation analyses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

The relationship between urinary Tamm-Horsfall glycoprotein excretion and urinary activity of glycosidases in normal pregnancy and pre-eclampsia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351356

24 September 2018

The dynamic responses of pro-inflammatory and anti-inflammatory cytokines of human mononuclear cells induced by uromodulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.348243

21 January 2018

Native cytokines do not bind to uromodulin (Tamm-Horsfall glycoprotein)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and tissue pharmacokinetics of human interferon-alpha in the rat after its intravenous administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution and clearance of radiolabeled human interleukin-1 beta in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clearance and tissue distribution of recombinant human interleukin 1 beta in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that specific high-mannose oligosaccharides can directly inhibit antigen-driven T-cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressive activity of tamm-horsfall glycoprotein oligosaccharides: Effect of removal of outer sugars and conjugation with a protein carrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pregnancy-associated changes in oligomannose oligosaccharides of human and bovine uromodulin (Tamm-Horsfall glycoprotein)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked reduction of Tamm-Horsfall protein synthesis in hyperprostaglandin E-syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary excretion rate of NC1 and Tamm-Horsfall protein in the microalbuminuric type I diabetic patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal tubular function modulates urinary levels of interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of Tamm-Horsfall protein excretion in hypertensive patients and type 1 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Errors in reported association between Tamm-Horsfall protein and IgG

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamm-Horsfall protein updated

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased excretions of beta2-microglobulin, IL-6, and IL-8 and decreased excretion of Tamm-Horsfall glycoprotein in urine of patients with active lupus nephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of Tamm-Horsfall protein to complement 1q measured by ELISA and resonant mirror biosensor techniques under various ionic-strength conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of mouse THP gene promoter and demonstration of its kidney-specific activity in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of Tamm-Horsfall protein to complement 1q and complement 1, including influence of hydrogen-ion concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal tubule-specific expression and urinary secretion of human growth hormone: a kidney-based transgenic bioreactor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of Polypeptide Hormones by the Normal Kidney and in Uremia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum Tamm-Horsfall glycoprotein levels in health and in renal disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kidney is the main site of interferon catabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamm-Horsfall glycoprotein in human amniotic fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of human 125I-interferon alpha by isolated perfused rabbit kidney and liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uromodulin: an immunoregulatory glycoprotein isolated from pregnancy urine that binds to and regulates the activity of interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uromodulin. An immunosuppressive 85-kilodalton glycoprotein isolated from human pregnancy urine is a high affinity ligand for recombinant interleukin 1 alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro evidence that carbohydrate moieties derived from uromodulin, an 85,000 dalton immunosuppressive glycoprotein isolated from human pregnancy urine, are immunosuppressive in the absence of intact protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronounced decrease of Tamm-Horsfall proteinuria in diabetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamm-Horsfall protein or uromodulin: new ideas about an old molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.348243

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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