(Q35980504)

11 August 2017

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title

High-avidity CD8+ T cells: optimal soldiers in the war against viruses and tumors (English)

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11 August 2017

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Martha A Alexander-Miller

series ordinal

1

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11 August 2017

1 January 2005

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11 August 2017

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11 August 2017

31

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11 August 2017

13-24

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11 August 2017

1

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https://scigraph.springernature.com/pub.10.1385/ir:31:1:13

11 August 2017

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cites work

High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.

1 reference

12 December 2020

Analysis of successful immune responses in persons infected with hepatitis C virus

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12 December 2020

Cutting Edge: Predetermined Avidity of Human CD8 T Cells Expanded on Calibrated MHC/Anti-CD28-Coated Microspheres

1 reference

12 December 2020

Simian immunodeficiency virus (SIV) infection of a rhesus macaque induces SIV-specific CD8(+) T cells with a defect in effector function that is reversible on extended interleukin-2 incubation

1 reference

12 December 2020

Selective induction of high avidity CTL by altering the balance of signals from APC.

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12 December 2020

High avidity CD8+ T cells are the initial population elicited following viral infection of the respiratory tract.

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12 December 2020

High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.

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12 December 2020

An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro

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12 December 2020

Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.

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12 December 2020

Viral immune evasion due to persistence of activated T cells without effector function

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12 December 2020

Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen

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12 December 2020

Induction of apoptosis in mature T cells by tumour necrosis factor

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12 December 2020

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

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12 December 2020

Manipulation of avidity to improve effectiveness of adoptively transferred CD8(+) T cells for melanoma immunotherapy in human MHC class I-transgenic mice

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12 December 2020

Molecular mechanisms and biological significance of CTL avidity

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12 December 2020

T cell affinity maturation by selective expansion during infection

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12 December 2020

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense

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12 December 2020

Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes

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12 December 2020

Live-cell dynamics and the role of costimulation in immunological synapse formation

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12 December 2020

Functional differences between influenza A-specific cytotoxic T lymphocyte clones expressing dominant and subdominant TCR

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12 December 2020

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

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12 December 2020

MHC polymorphism can enrich the T cell repertoire of the species by shifts in intrathymic selection

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12 December 2020

Molecular interactions mediating T cell antigen recognition

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12 December 2020

Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus

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12 December 2020

Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity

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12 December 2020

Cutting edge: lipid raft integrity affects the efficiency of MHC class I tetramer binding and cell surface TCR arrangement on CD8+ T cells

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12 December 2020

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection

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12 December 2020

Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression

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12 December 2020

A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5

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12 December 2020

Peripheral clonal deletion of antiviral memory CD8+ T cells.

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12 December 2020

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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12 December 2020

Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution.

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12 December 2020

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

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12 December 2020

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

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12 December 2020

Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

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12 December 2020

The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained.

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12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

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12 December 2020

In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity

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12 December 2020

Assessing CD8 T cell number and dysfunction in the presence of antigen

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12 December 2020

Diverse expansion potential and heterogeneous avidity in tumor-associated antigen-specific T lymphocytes from primary melanoma patients

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12 December 2020

Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides

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12 December 2020

Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL

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12 December 2020

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

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12 December 2020

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

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12 December 2020

Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity

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12 December 2020

Generation of CD8(+) T cell memory in response to low, high, and excessive levels of epitope

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12 December 2020

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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12 December 2020

Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

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12 December 2020

Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells.

1 reference

12 December 2020

Identifiers

DOI

10.1385/IR:31:1:13

1 reference

PubMed ID

15591619

Dimensions Publication ID

11 August 2017

0 references

1 reference

PubMed ID

15591619