(Q35987823)

11 August 2017

Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis (English)

1 reference

11 August 2017

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Isobel A Scarisbrick

1

1 reference

11 August 2017

Hyesook Yoon

2

1 reference

11 August 2017

Michael Panos

3

1 reference

11 August 2017

Nadya Larson

4

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11 August 2017

Sachiko I Blaber

5

1 reference

11 August 2017

Michael Blaber

6

1 reference

11 August 2017

Moses Rodriguez

7

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11 August 2017

21 March 2012

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11 August 2017

1 reference

11 August 2017

22

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11 August 2017

5

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11 August 2017

709-722

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Kallikrein 6 is a novel molecular trigger of reactive astrogliosis.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Functional role of kallikrein 6 in regulating immune cell survival

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Transgenic expression of viral capsid proteins predisposes to axonal injury in a murine model of multiple sclerosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Fibrinogen depleting agent batroxobin has a beneficial effect on experimental autoimmune encephalomyelitis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Human HLA-DR Transgenes Protect Mice from Fatal Virus-Induced Encephalomyelitis and Chronic Demyelination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

The multiple sclerosis degradome: enzymatic cascades in development and progression of central nervous system inflammatory disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Dynamic role of kallikrein 6 in traumatic spinal cord injury

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Human and mouse proteases: a comparative genomic approach

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Transgenic expression of Theiler's murine encephalomyelitis virus genes in H-2(b) mice inhibits resistance to virus-induced demyelination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Activity of a newly identified serine protease in CNS demyelination

2 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

2 October 2017

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Enzymatic properties of rat myelencephalon-specific protease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Assessment of hindlimb gait as a powerful indicator of axonal loss in a murine model of progressive CNS demyelination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Quantitative assessment of neurologic deficits in a chronic progressive murine model of CNS demyelination.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Multiple sclerosis (first of two parts).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Pathogenesis of multiple sclerosis. A critical reappraisal

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Theiler's murine encephalomyelitis: a model of demyelination and persistence of virus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Degradation of myelin basic protein by cerebrospinal fluid: Preservation of antigenic determinants under physiological conditions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Identification of novel candidate protein biomarkers for the post-polio syndrome - implications for diagnosis, neurodegeneration and neuroinflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood-brain barrier injury

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. VI. Potentiation of demyelination with and characterization of an immunopathologic CD4+ T cell line specific for an immunodominant VP2 ep

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Complement potentiates the degradation of myelin proteins by plasmin: implications for a mechanism of inflammatory demyelination

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects

11 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Cerebrospinal fluid and serum levels and intrathecal production of active matrix metalloproteinase-9 (MMP-9) as markers of disease activity in patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Granule-derived granzyme B mediates the vulnerability of human neurons to T cell-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Differential transcription of matrix-metalloproteinase genes in primary mouse astrocytes and microglia infected with Theiler's murine encephalomyelitis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in cerebrospinal fluid differ in multiple sclerosis and Devic's neuromyelitis optica.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Potential scope of action of tissue kallikreins in CNS immune-mediated disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Matrix metalloproteinases and their tissue inhibitors in cuprizone-induced demyelination and remyelination of brain white and gray matter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Interferon beta-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Expression of myelencephalon-specific protease in transient middle cerebral artery occlusion model of rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

MMP-12, MMP-3, and TIMP-1 are markedly upregulated in chronic demyelinating theiler murine encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Activation profiles and regulatory cascades of the human kallikrein-related peptidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Targeting kallikrein 6 proteolysis attenuates CNS inflammatory disease

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Nervous system-specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360139

Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine

24 September 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

The Expression of Tissue-type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the Central Nervous System in Multiple Sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Leukocyte Gelatinase B Cleavage Releases Encephalitogens from Human Myelin Basic Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00577.X

Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

12 December 2020

Gelatinases (MMP-2 and MMP-9) are preferentially expressed by Th1 vs. Th2 cells

1 reference

12 December 2020

Serum MMP-9 and TIMP-1 levels are related to MRI activity in relapsing multiple sclerosis

1 reference

12 December 2020

The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis

1 reference

12 December 2020

Preservation of neurologic function during inflammatory demyelination correlates with axon sparing in a mouse model of multiple sclerosis

1 reference

12 December 2020

Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis

1 reference

12 December 2020

Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window

1 reference

12 December 2020

Human Kallikrein 6 Cerebrospinal Levels are Elevated in Multiple Sclerosis

1 reference

12 December 2020

10.1111/J.1750-3639.2012.00577.X

Identifiers

DOI

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22335454

1 reference