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Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation.
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3360587
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24 January 2020
title
Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation
(English)
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PMC publication ID
3360587
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21385577%20AND%20SRC:MED&resulttype=core&format=json
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24 January 2020
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Bin Zhou
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2
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24 January 2020
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N L Manuylov
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1
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3360587
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24 January 2020
Q Ma
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3
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24 January 2020
S C Fox
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4
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24 January 2020
W T Pu
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5
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24 January 2020
S G Tevosian
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6
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3360587
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English
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6 March 2011
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24 January 2020
published in
Developmental Biology
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24 January 2020
volume
353
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24 January 2020
issue
2
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3360587
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24 January 2020
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229-241
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24 January 2020
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FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression
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The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila
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Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
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Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
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FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium
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Endogenous expression of Müllerian inhibiting substance in early postnatal rat sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites
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Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development
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2 October 2017
Transcription factor GATA-4 enhances Müllerian inhibiting substance gene transcription through a direct interaction with the nuclear receptor SF-1.
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FOG-2, a heart- and brain-enriched cofactor for GATA transcription factors
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Mammalian sex determination: a molecular drama
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2 October 2017
Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes
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FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped
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2 October 2017
Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter.
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2 October 2017
Evidence for evolutionary conservation of sex-determining genes
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2 October 2017
Expression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovary
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Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis
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GATA4 transcription factor is required for ventral morphogenesis and heart tube formation
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2 October 2017
Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds
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2 October 2017
The expression pattern of a mouse doublesex-related gene is consistent with a role in gonadal differentiation.
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Expression and regulation of transcription factors GATA-4 and GATA-6 in developing mouse testis
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Sex determination: the power of DMRT1.
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Ovarian development in mice requires the GATA4-FOG2 transcription complex.
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Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity.
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Development of a steroidogenic factor 1/Cre transgenic mouse line.
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24 September 2018
Testatin transgenic and knockout mice exhibit normal sex-differentiation.
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24 September 2018
Sox9 is sufficient for functional testis development producing fertile male mice in the absence of Sry.
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24 September 2018
Expression of the GATA-4 and GATA-6 transcription factors in the fetal rat gonad and in the ovary during postnatal development and pregnancy.
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24 September 2018
Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2.
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24 September 2018
Heat shock-initiated apoptosis is accelerated and removal of damaged cells is delayed in the testis of clusterin/ApoJ knock-out mice
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Expression of transcription factor GATA-4 during human testicular development and disease.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3360587
retrieved
24 September 2018
Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.02.032
retrieved
7 January 2021
Sex determination: Birds do it with a Z gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.02.032
retrieved
7 January 2021
Fog2 excision in mice leads to premature mammary gland involution and reduced Esr1 gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.02.032
retrieved
7 January 2021
Identifiers
DOI
10.1016/J.YDBIO.2011.02.032
1 reference
stated in
Europe PubMed Central
PMC publication ID
3360587
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21385577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
Fatcat ID
release_k7y3hjqugrdk3bxjkjqdmq5lge
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/k7y3hjqugrdk3bxjkjqdmq5lge
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3360587
1 reference
stated in
Europe PubMed Central
PMC publication ID
3360587
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21385577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
PubMed publication ID
21385577
1 reference
stated in
Europe PubMed Central
PMC publication ID
3360587
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21385577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
ResearchGate publication ID
50347733
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