(Q35995199)

English

1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

based on heuristic

inferred from title

primary metabolite

1 reference

based on heuristic

inferred from title

Stefan Chlopicki

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Andrzej Mogielnicki

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Magdalena Bartus

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Jerzy Marian Gębicki

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

J Swies

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

W Buczko

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

M Lomnicka

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

J Adamus

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

language of work or name

0 references

publication date

16 July 2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

British Journal of Pharmacology

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

152

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

230-239

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Beraprost sodium, a prostacyclin (PGI) analogue, ameliorates concanavalin A-induced liver injury in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Prevention of experimental carotid and coronary artery thrombosis by the glycoprotein IIb/IIIa receptor antagonist CRL42796

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Comparison of endothelial pleiotropic actions of angiotensin converting enzyme inhibitors and statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Cyclo-oxygenase products and atherothrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Human nicotinamide N-methyltransferase pharmacogenetics: gene sequence analysis and promoter characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Focus on prostacyclin and its novel mimetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Prostaglandins, platelets, and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

2 October 2017

Bioassay of prostacyclin and endothelium-derived relaxing factor (EDRF) from porcine aortic endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

11 July 2018

Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Paradoxical effects of fenofibrate and nicotinic acid in apo E-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Redox regulation: a new challenge for pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Nicotinamide trials in diabetes intervention. Does a metabolite provide benefit?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Antithrombotic effect of L-arginine in hypertensive rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Nicotinamide inhibits endotoxin-induced monocyte tissue factor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

An efficient chemical synthesis of nicotinamide riboside (NAR) and analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

CNS-specific prostacyclin ligands as neuronal survival-promoting factors in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978255

23 September 2018

N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effect of tissue and plasma type angiotensin converting enzyme inhibitors in experimental thrombosis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Pyridylcarbinol (Ronicol) releases a prostacyclin-like substance into arterial blood of patients with arteriosclerosis obliterans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of disaggregatory prostanoids into circulation by nicotinic alcohol, nicotinic acid and nicotinamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of renal tubular secretion in man, in health and disease, using endogenous N-1-methylnicotinamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of antithrombotic drugs in a rat model of aspirin-insensitive arterial thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effect of enalapril, an angiotensin-converting enzyme inhibitor, on venous thrombosis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombolytic and antiplatelet action of xanthinol nicotinate (Sadamin): possible mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some aspects of tryptophan metabolism in human subjects. I. Nitrogen balances, blood pyridine nucleotides and urinary excretion of N1-methylnicotinamide and N1-methyl-2-pyridone-5-carboxamide on a low-niacin diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II enhances thrombosis development in renovascular hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human nicotinamide N-methyltransferase pharmacogenetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0707383

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.BJP.0707383

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17641676%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35995199&oldid=1966354891"