(Q35997281)

11 August 2017

Clinical features and treatment of maturity onset diabetes of the young (MODY). (English)

1 reference

11 August 2017

Daphne Sl Gardner

1

1 reference

PMCID

3363133

11 August 2017

E Shyong Tai

series ordinal

2

1 reference

11 August 2017

1 May 2012

1 reference

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

11 August 2017

1 reference

11 August 2017

5

1 reference

11 August 2017

101-108

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

11 August 2017

start time

1 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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2 October 2017

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Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

2 October 2017

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High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes

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Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations

2 October 2017

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2 October 2017

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Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein

2 October 2017

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Long-term follow-up of oral glucose tolerance test-derived glucose tolerance and insulin secretion and insulin sensitivity indexes in subjects with glucokinase mutations (MODY2).

2 October 2017

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Best practice guidelines for the molecular genetic diagnosis of maturity-onset diabetes of the young

2 October 2017

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Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene

2 October 2017

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Hepatocyte nuclear factor-1 beta mutations cause neonatal diabetes and intrauterine growth retardation: support for a critical role of HNF-1? in human pancreatic development

2 October 2017

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Minireview: pharmacogenetics and beyond: the interaction of therapeutic response, beta-cell physiology, and genetics in diabetes

2 October 2017

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Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction

2 October 2017

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Genetic and clinical characteristics of maturity-onset diabetes of the young in Chinese patients

2 October 2017

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Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY).

2 October 2017

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Mitochondrial diabetes: molecular mechanisms and clinical presentation

2 October 2017

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Genetic cause of hyperglycaemia and response to treatment in diabetes

2 October 2017

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Renal cysts and diabetes syndrome linked to mutations of the hepatocyte nuclear factor-1 beta gene: description of a new family with associated liver involvement

2 October 2017

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Predictive genetic testing in maturity-onset diabetes of the young (MODY).

2 October 2017

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beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors

2 October 2017

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HNF1alpha controls renal glucose reabsorption in mouse and man.

2 October 2017

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Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes

2 October 2017

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Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

2 October 2017

1 reference

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Essential role for the homeoprotein vHNF1/HNF1beta in visceral endoderm differentiation

2 October 2017

1 reference

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Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.

2 October 2017

1 reference

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Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice

2 October 2017

1 reference

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Novel mutations and a mutational hotspot in the MODY3 gene

2 October 2017

1 reference

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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Mild familial diabetes with dominant inheritance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites.

2 October 2017

1 reference

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Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Renal phenotypes related to hepatocyte nuclear factor-1beta (TCF2) mutations in a pediatric cohort

2 October 2017

1 reference

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Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Mutations in the hepatocyte nuclear factor-1alpha/MODY3 gene in Japanese subjects with early- and late-onset NIDDM.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Insulin and proinsulin secretion in subjects with abnormal glucose tolerance and a mitochondrial tRNA(Leu(UUR)) mutation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

A novel PAX4 mutation in a Japanese patient with maturity-onset diabetes of the young.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Familial young-onset forms of diabetes related to HNF4A and rare HNF1A molecular aetiologies.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Increased all-cause and cardiovascular mortality in monogenic diabetes as a result of mutations in the HNF1A gene

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Phenotypical aspects of maturity-onset diabetes of the young (MODY diabetes) in comparison with Type 2 diabetes mellitus (T2DM) in children and adolescents: experience from a large multicentre database.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Neonatal diabetes mellitus with pancreatic agenesis in an infant with homozygous IPF-1 Pro63fsX60 mutation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

A genetic diagnosis of HNF1A diabetes alters treatment and improves glycaemic control in the majority of insulin-treated patients.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Mutations in GCK and HNF-1alpha explain the majority of cases with clinical diagnosis of MODY in Spain.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

PAX4 mutations in Thais with maturity onset diabetes of the young

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential expression in the pancreas and define the relationship between mutation position and clinical phenotype in monogenic diabetes.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Improved prandial glucose control with lower risk of hypoglycemia with nateglinide than with glibenclamide in patients with maturity-onset diabetes of the young type 3.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Beta-cell dysfunction, insulin sensitivity, and glycosuria precede diabetes in hepatocyte nuclear factor-1alpha mutation carriers

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

No deterioration in glycemic control in HNF-1alpha maturity-onset diabetes of the young following transfer from long-term insulin to sulphonylureas

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

The genetic abnormality in the beta cell determines the response to an oral glucose load

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Early-onset Type II diabetes mellitus in Italian families due to mutations in the genes encoding hepatic nuclear factor 1 alpha and glucokinase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Genetic and clinical characterisation of maturity-onset diabetes of the young in Spanish families.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Hyperexcitability to sulphonylurea in MODY3.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Administration of sulfonylureas can increase glucose-induced insulin secretion for decades in patients with maturity-onset diabetes of the young.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

High frequency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Maturity-onset diabetes of the young (MODY): how many cases are we missing?

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

Molecular genetics and phenotypic characteristics of MODY caused by hepatocyte nuclear factor 4α mutations in a large European collection

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3363133

A novel mutation, Ser159Pro in the NeuroD1/BETA2 gene contributes to the development of diabetes in a Chinese potential MODY family

14 November 2018

1 reference

12 December 2020

Islet autoantibodies can discriminate maturity-onset diabetes of the young (MODY) from Type 1 diabetes

1 reference

12 December 2020

In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243

1 reference

12 December 2020

Identification of new mutations in the hepatocyte nuclear factor 4alpha gene among families with early onset Type 2 diabetes mellitus

1 reference

12 December 2020

Maturity-onset diabetes of the young. Studies in a Norwegian family

1 reference

12 December 2020

Liver and kidney function in Japanese patients with maturity-onset diabetes of the young

1 reference

12 December 2020

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

1 reference

12 December 2020

Evolution of the glucokinase glucose sensor paradigm for pancreatic beta cells

1 reference

12 December 2020

Diagnosis, management, and prognosis of HNF1B nephropathy in adulthood

1 reference

12 December 2020

A Difference Between the Inheritance of Classical Juvenile-onset and Maturity-onset Type Diabetes of Young People

1 reference

12 December 2020

Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families

1 reference

12 December 2020

Chronic diabetic complications in patients with MODY3 diabetes

1 reference

12 December 2020

Clinical characteristics and diagnostic criteria of maturity-onset diabetes of the young (MODY) due to molecular anomalies of the HNF1A gene

1 reference

12 December 2020

Mutations in the Hepatocyte Nuclear Factor-1 Gene Are a Common Cause of Maturity-Onset Diabetes of the Young in the U.K

1 reference

12 December 2020

Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1alpha gene mutations: evidence for pharmacogenetics in diabetes

1 reference

12 December 2020

Asian MODY: are we missing an important diagnosis?

1 reference

12 December 2020

Influence of maternal and fetal glucokinase mutations in gestational diabetes

1 reference

12 December 2020

Identifiers

DOI

10.2147/DMSO.S23353

1 reference

release_6lny5aerwfehzo3zr4n56stgle

11 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6lny5aerwfehzo3zr4n56stgle

24 November 2022

mapped directly with Wikidata item

PMCID

3363133

1 reference

11 August 2017

1 reference

PMCID

3363133