Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35999249)
Watch
English
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
title
Targeting survivin and p53 in pediatric acute lymphoblastic leukemia
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
main subject
leukemia
1 reference
based on heuristic
inferred from title
author
Jeffrey W. Tyner
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
Brian Druker
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
Bill H. Chang
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
author name string
A M Jemal
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
M Thayer
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
publication date
30 September 2011
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
volume
26
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
page(s)
623-632
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2011.249
0 references
cites work
Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Aurora B kinase activation requires survivin priming phosphorylation by PLK1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Up-regulation of survivin by the E2A-HLF chimera is indispensable for the survival of t(17;19)-positive leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Survivin: a new target for anti-cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
RNAi screen for rapid therapeutic target identification in leukemia patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Survivin and its prognostic significance in pediatric acute B-cell precursor lymphoblastic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
ABCB1 over-expression and drug-efflux in acute lymphoblastic leukemia cell lines with t(17;19) and E2A-HLF expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Survivin splice variants regulate the balance between proliferation and cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Identification of a novel splice variant of the human anti-apoptopsis gene survivin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Transcriptional analysis of human survivin gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Fifty years of studies of the biology and therapy of childhood leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
2 October 2017
Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
11 July 2018
YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
23 September 2018
Profiling of DNA replication timing in unsynchronized cell populations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
23 September 2018
Survivin regulates the p53 tumor suppressor gene family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
23 September 2018
Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
23 September 2018
Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364442
retrieved
23 September 2018
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21960246
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34(+) cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21960246
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutations of the p53 gene in B-cell lymphoblastic acute leukemia: a report on 60 cases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21960246
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/LEU.2011.249
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PMCID
3364442
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PubMed ID
21960246
1 reference
stated in
Europe PubMed Central
PMCID
3364442
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21960246%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
ResearchGate publication ID
51682426
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit