(Q36002630)

English

High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1

scholarly article

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1 (English)

1 reference

Europe PubMed Central

11 August 2017

1 reference

based on heuristic

inferred from title

7-oxocholesterol

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Naoki Terasaka

1

1 reference

Europe PubMed Central

11 August 2017

Nan Wang

2

1 reference

Europe PubMed Central

11 August 2017

Laurent Yvan-Charvet

3

1 reference

Europe PubMed Central

11 August 2017

Alan R Tall

4

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

10 September 2007

1 reference

Europe PubMed Central

11 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

11 August 2017

104

1 reference

Europe PubMed Central

11 August 2017

15093-15098

1 reference

Europe PubMed Central

11 August 2017

38

1 reference

Europe PubMed Central

11 August 2017

Molecular regulation of HDL metabolism and function: implications for novel therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Mechanisms of disease: proatherogenic HDL--an evolving field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Cellular physiology of cholesterol efflux in vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Antiinflammatory properties of HDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Lipids: potential regulators of nitric oxide generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

HDL cholesterol and protective factors in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Role of ABC transporters in secretion of cholesterol from liver into bile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

The role of high-density lipoproteins in oxidation and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Oxidized low-density lipoprotein is associated with apoptosis of vascular smooth muscle cells in human atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Atherosclerosis — An Inflammatory Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Serum Lipoproteins and Coronary Heart Disease in a Population Study of Hawaii Japanese Men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

2 October 2017

Esterification of oxysterols by human plasma lecithin-cholesterol acyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

11 July 2018

Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

11 July 2018

Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Nitric oxide prevents oxidised LDL-induced p53 accumulation, cytochrome c translocation, and apoptosis in macrophages via guanylate cyclase stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Oxysterols induce interleukin-1beta production in human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Changes in vimentin in human macrophages during apoptosis induced by oxidised low density lipoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986618

23 September 2018

Active oxygen species and lysophosphatidylcholine are involved in oxidized low density lipoprotein activation of smooth muscle cell DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

25-Hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free and esterified oxysterol: formation during copper-oxidation of low density lipoprotein and uptake by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cholesterol oxidation products formed by oxidative modification of low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary oxysterols are incorporated in plasma triglyceride-rich lipoproteins, increase their susceptibility to oxidation and increase aortic cholesterol concentration of rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxysterols and atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid hepatic metabolism of 7-ketocholesterol in vivo: implications for dietary oxysterols

1 reference

https://pubmed.ncbi.nlm.nih.gov/17846428

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0704602104

1 reference

Europe PubMed Central

11 August 2017

2007PNAS..10415093T

0 references

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

ResearchGate publication ID

0 references

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