(Q36003721)

11 August 2017

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title

Daptomycin: a cyclic lipopeptide antimicrobial agent (English)

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11 August 2017

LilyAnn Jeu

1

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11 August 2017

Horatio B Fung

series ordinal

2

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11 August 2017

publication date

1 November 2004

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11 August 2017

published in

Clinical Therapeutics

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11 August 2017

volume

26

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11 August 2017

issue

11

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11 August 2017

page(s)

1728-1757

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Activity of LY146032 in vitro and in experimental enterococcal pyelonephritis

11 August 2017

cites work

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12 December 2020

Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid

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12 December 2020

Scanning electronmicroscopy of Staphylococcus aureus and Enterococcus faecalis exposed to daptomycin.

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12 December 2020

Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania

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12 December 2020

Resistance studies with daptomycin

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12 December 2020

Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene

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12 December 2020

Clinical pharmacokinetics of daptomycin

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12 December 2020

Comparison of daptomycin, vancomycin, and ampicillin-gentamicin for treatment of experimental endocarditis caused by penicillin-resistant enterococci

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12 December 2020

Moderate liver impairment has no influence on daptomycin pharmacokinetics

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12 December 2020

Baseline Study To Determine In Vitro Activities of Daptomycin against Gram-Positive Pathogens Isolated in the United States in 2000-2001

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12 December 2020

Pharmacodynamics of daptomycin and vancomycin on Enterococcus faecalis and Staphylococcus aureus demonstrated by studies of initial killing and postantibiotic effect and influence of Ca2+ and albumin on these drugs

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12 December 2020

Antibacterial susceptibility of a vancomycin-resistant Staphylococcus aureus strain isolated at the Hershey Medical Center

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12 December 2020

Endocarditis due to high level gentamicin resistant Enterococcus faecium

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12 December 2020

Analysis of daptomycin efficacy and breakpoint standards in a murine model of Enterococcus faecalis and Enterococcus faecium renal infection

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12 December 2020

Efficacy of Daptomycin in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

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12 December 2020

In vitro and in vivo activity of LY 146032, a new cyclic lipopeptide antibiotic

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12 December 2020

Once-daily dosing in dogs optimizes daptomycin safety

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12 December 2020

Staphylococcus aureus with reduced susceptibility to vancomycin--United States, 1997.

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12 December 2020

Linezolid resistance in a clinical isolate of Staphylococcus aureus

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12 December 2020

A21978C, a complex of new acidic peptide antibiotics: isolation, chemistry, and mass spectral structure elucidation

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12 December 2020

Daptomycin (LY146032) treatment of experimental enterococcal endocarditis

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12 December 2020

Lipoteichoic acid as a new target for activity of antibiotics: mode of action of daptomycin (LY146032)

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12 December 2020

Identification of daptomycin-binding proteins in the membrane of Enterococcus hirae

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12 December 2020

Structural transitions as determinants of the action of the calcium-dependent antibiotic daptomycin

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12 December 2020

Single-dose pharmacokinetics and antibacterial activity of daptomycin, a new lipopeptide antibiotic, in healthy volunteers

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12 December 2020

Lipoteichoic acid as a target for antimicrobial action

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12 December 2020

Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infection

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12 December 2020

Inhibition of peptidoglycan biosynthesis in gram-positive bacteria by LY146032

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12 December 2020

In vitro activities of daptomycin against 2,789 clinical isolates from 11 North American medical centers

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12 December 2020

Fluorescence indicates a calcium-dependent interaction between the lipopeptide antibiotic LY146032 and phospholipid membranes.

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12 December 2020

Daptomycin activity and spectrum: a worldwide sample of 6737 clinical Gram-positive organisms

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12 December 2020

Daptomycin for line-related Leuconostoc bacteraemia

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12 December 2020

Optimal treatment of complicated skin and skin structure infections

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12 December 2020

The role of acyl chain character and other determinants on the bilayer activity of A21978C an acidic lipopeptide antibiotic

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12 December 2020

Geographic variations and trends in antimicrobial resistance among Enterococcus faecalis and Enterococcus faecium in the SENTRY Antimicrobial Surveillance Program (1997–2000)

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12 December 2020

Reduced susceptibility of Staphylococcus aureus to vancomycin--Japan, 1996

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12 December 2020

Molecular basis of the inhibition of gentamicin nephrotoxicity by daptomycin; an infrared spectroscopic investigation

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12 December 2020

In-vitro activity of LY 146032, a novel cyclic lipopeptide, alone and in combination with gentamicin or tobramycin against enterococci

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12 December 2020

Influence of daptomycin on staphylococcal abscesses and experimental tobramycin nephrotoxicity

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12 December 2020

Daptomycin susceptibility tests: interpretive criteria, quality control, and effect of calcium on in vitro tests.

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12 December 2020

Staphylococcus aureus resistant to vancomycin--United States, 2002.

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12 December 2020

In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against Staphylococci and Enterococci, including vancomycin- intermediate and -resistant strains

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12 December 2020

Linezolid-resistant, vancomycin-resistant Enterococcus faecium infection in patients without prior exposure to linezolid

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12 December 2020

Treatment of chronic experimental Staphylococcus aureus osteomyelitis with LY146032 and vancomycin

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12 December 2020

The activity of daptomycin on Enterococcus faecium protoplasts: indirect evidence supporting a novel mode of action on lipoteichoic acid synthesis

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12 December 2020

Bactericidal activity of daptomycin against vancomycin-resistantEnterococcus faecium in an in vitro pharmacokinetic model

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12 December 2020

Activity of daptomycin against Gram-positive pathogens: a comparison with other agents and the determination of a tentative breakpoint

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12 December 2020

LY146032, alone and in combination with gentamicin, for the treatment of enterococcal pyelonephritis in the rat model

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12 December 2020

Pharmacokinetics and bactericidal rates of daptomycin and vancomycin in intravenous drug abusers being treated for gram-positive endocarditis and bacteremia

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12 December 2020

Postantibiotic effects of daptomycin against 14 staphylococcal and pneumococcal clinical isolates

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12 December 2020

Comparative evaluation of daptomycin (LY146032) and vancomycin in the treatment of experimental methicillin-resistant Staphylococcus aureus osteomyelitis in rabbits

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12 December 2020

Vancomycin-resistant Staphylococcus aureus--New York, 2004.

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12 December 2020

Effect of protein binding of daptomycin on MIC and antibacterial activity

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12 December 2020

Daptomycin pharmacokinetics and safety following administration of escalating doses once daily to healthy subjects

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12 December 2020

Bactericidal activities of two daptomycin regimens against clinical strains of glycopeptide intermediate-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and methicillin-resistant Staphylococcus aureus isolates in an in vi

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12 December 2020

In vitro activity of LY146032 against gram-positive bacteria.

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12 December 2020

In vivo pharmacodynamic activity of daptomycin

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12 December 2020

Synergy of daptomycin with oxacillin and other beta-lactams against methicillin-resistant Staphylococcus aureus

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12 December 2020

Daptomycin structure and mechanism of action revealed.

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12 December 2020

Daptomycin may attenuate experimental tobramycin nephrotoxicity by electrostatic complexation to tobramycin

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12 December 2020

Population pharmacokinetics of daptomycin

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12 December 2020

Modulation of phospholipase A2 activity by aminoglycosides and daptomycin: a Fourier transform infrared spectroscopic study

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12 December 2020

Vancomycin-resistant Staphylococcus aureus--Pennsylvania, 2002.

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12 December 2020

Treatment of experimental endocarditis caused by a beta-lactamase-producing strain of Enterococcus faecalis with high-level resistance to gentamicin

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12 December 2020

The in vitro activity of daptomycin against 514 Gram-positive aerobic clinical isolates

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12 December 2020

Pharmacokinetics and inflammatory fluid penetration of intravenous daptomycin in volunteers

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12 December 2020

Daptomycin compared with teicoplanin and vancomycin for therapy of experimental Staphylococcus aureus endocarditis

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12 December 2020

Inhibition of membrane potential-dependent amino acid transport by daptomycin

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12 December 2020

Experimental studies on nephrotoxicity and pharmacokinetics of LY 146032 (daptomycin) in rats

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12 December 2020

In vivo activity of the combination of daptomycin and fosfomycin compared with daptomycin alone against a strain of Enterococcus faecalis with high-level gentamicin resistance in the rat endocarditis model

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12 December 2020

The safety and efficacy of daptomycin for the treatment of complicated skin and skin-structure infections

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12 December 2020

Pharmacodynamic profile of daptomycin against Enterococcus species and methicillin-resistant Staphylococcus aureus in a murine thigh infection model

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12 December 2020

Comparative efficacy of daptomycin, vancomycin, and cloxacillin for the treatment of Staphylococcus aureus endocarditis in rats and role of test conditions in this determination

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12 December 2020

Single-dose pharmacokinetics of daptomycin in young and geriatric volunteers

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12 December 2020

Activity of daptomycin against susceptible and multidrug-resistant Gram-positive pathogens collected in the SECURE study (Europe) during 2000-2001.

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12 December 2020

Linezolid-resistant Enterococcus faecium isolated from a patient without prior exposure to an oxazolidinone: report from the SENTRY Antimicrobial Surveillance Program

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12 December 2020

Staphylococcus aureus ventriculitis treated with single-dose intraventricular vancomycin or daptomycin (LY146032): bacterial and antibiotic kinetics in hydrocephalic rabbits

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12 December 2020

Daptomycin synergy with rifampicin and ampicillin against vancomycin-resistant enterococci

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12 December 2020

Delayed discovery of linezolid-resistant, vancomycin-resistant Enterococcus faecium: lessons learned

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12 December 2020

National Nosocomial Infections Surveillance (NNIS) System Report, Data Summary from January 1990-May 1999, issued June 1999. A report from the NNIS System

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12 December 2020

Impact of LY146032 on Streptococcus (Enterococcus) faecalis translocation in mice

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12 December 2020

The in vitro activity of daptomycin against Staphylococcus aureus and Enterococcus species

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12 December 2020

Comparison of the investigational drug, LY146032, with vancomycin in experimental pneumonia due to methicillin-resistant Staphylococcus aureus

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12 December 2020

The lipopeptide antibiotic A21978C has a specific interaction with DMPC only in the presence of calcium ions

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12 December 2020

In vitro bactericidal activities of daptomycin against Staphylococcus aureus and Enterococcus faecalis are not mediated by inhibition of lipoteichoic acid biosynthesis

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12 December 2020

Daptomycin versus vancomycin treatment for Staphylococcus aureus bacteremia in a murine model.

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12 December 2020

Subcellular distribution of daptomycin given alone or with tobramycin in renal proximal tubular cells

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12 December 2020

A practical guide to the treatment of complicated skin and soft tissue infections

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12 December 2020

Update: Staphylococcus aureus with reduced susceptibility to vancomycin--United States, 1997

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12 December 2020

Differential increased survival of staphylococci and limited ultrastructural changes in the core of infected fibrin clots after daptomycin administration.

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12 December 2020

Increased killing of staphylococci and streptococci by daptomycin compared with cefazolin and vancomycin in an in vitro peritoneal dialysate model

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12 December 2020

Correlation of daptomycin bactericidal activity and membrane depolarization in Staphylococcus aureus

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12 December 2020

Bactericidal activities of daptomycin, quinupristin-dalfopristin, and linezolid against vancomycin-resistant Staphylococcus aureus in an in vitro pharmacodynamic model with simulated endocardial vegetations

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12 December 2020

Nosocomial spread of linezolid-resistant, vancomycin-resistant Enterococcus faecium

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12 December 2020

Daptomycin disrupts membrane potential in growing Staphylococcus aureus

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12 December 2020

Comparative efficacy of daptomycin and vancomycin in the therapy of experimental foreign body infection due to Staphylococcus aureus

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12 December 2020

Therapeutic and preventative options for the management of vancomycin-resistant enterococcal infections

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12 December 2020

LY146032 in a hamster model of Staphylococcus aureus pneumonia--effect on in vivo clearance and mortality and in vitro opsonophagocytic killing.

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12 December 2020

In vivo verification of in vitro model of antibiotic treatment of device-related infection

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12 December 2020

Linezolid-resistant enterococci: report of the first isolates in the United Kingdom

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12 December 2020

Daptomycin or teicoplanin in combination with gentamicin for treatment of experimental endocarditis due to a highly glycopeptide-resistant isolate of Enterococcus faecium

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12 December 2020

Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: the synthesis and evaluation of daptomycin (LY146032)

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12 December 2020

Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposure.

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12 December 2020

Tobramycin and daptomycin disposition when co-administered to healthy volunteers

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12 December 2020

Treatment of Clostridium difficile colitis in hamsters with a lipopeptide antibiotic, LY146032.

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12 December 2020

Investigation of the early killing of Staphylococcus aureus by daptomycin by using an in vitro pharmacodynamic model

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12 December 2020

10.1016/J.CLINTHERA.2004.11.014

Identifiers

DOI

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11 August 2017

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