(Q36006972)

English

Atypical membrane-embedded phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2)-binding site on p47(phox) Phox homology (PX) domain revealed by NMR.

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Europe PubMed Central

PMC publication ID

11 August 2017

Atypical membrane-embedded phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2)-binding site on p47(phox) Phox homology (PX) domain revealed by NMR. (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Pavlos Stampoulis

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Takumi Ueda

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Masahiko Matsumoto

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Hiroaki Terasawa

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Kei Miyano

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Hideki Sumimoto

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Ichio Shimada

7

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Europe PubMed Central

PMC publication ID

11 August 2017

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publication date

4 April 2012

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Europe PubMed Central

PMC publication ID

11 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

11 August 2017

287

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Europe PubMed Central

PMC publication ID

11 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

17848-17859

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

NMR Analyses of the Gβγ Binding and Conformational Rearrangements of the Cytoplasmic Pore of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1)

1 reference

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NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers.

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2 October 2017

Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4.

1 reference

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2 October 2017

The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2)

1 reference

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2 October 2017

A region N-terminal to the tandem SH3 domain of p47phox plays a crucial role in the activation of the phagocyte NADPH oxidase

1 reference

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2 October 2017

Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation

1 reference

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Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species

1 reference

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2 October 2017

The PX-BAR membrane-remodeling unit of sorting nexin 9

1 reference

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Structural basis of the collagen-binding mode of discoidin domain receptor 2

1 reference

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Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity

1 reference

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2 October 2017

PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation

1 reference

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2 October 2017

Molecular mechanism of membrane docking by the Vam7p PX domain

1 reference

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2 October 2017

Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p

1 reference

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Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin

1 reference

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2 October 2017

NMR techniques for identifying the interface of a larger protein-protein complex: cross-saturation and transferred cross-saturation experiments

1 reference

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2 October 2017

Assembly of the phagocyte NADPH oxidase

1 reference

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2 October 2017

Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

Chronic granulomatous disease.

1 reference

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2 October 2017

Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

1 reference

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2 October 2017

Solution NMR techniques for large molecular and supramolecular structures

1 reference

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2 October 2017

Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

Solution structure of the Vam7p PX domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

The Phox homology (PX) domain, a new player in phosphoinositide signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

Location, location, location: membrane targeting directed by PX domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

2 October 2017

Solution structure of the PX domain, a target of the SH3 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366843

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Parameters influencing the determination of liposome lamellarity by 31P-NMR.

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Clinical aspects of chronic granulomatous disease

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2 October 2017

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

1 reference

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2 October 2017

NADPH oxidase: an update

1 reference

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Distinct targeting and fusion functions of the PX and SNARE domains of yeast vacuolar Vam7p.

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The PX domain as a novel phosphoinositide- binding module

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The p40phox and p47phox PX domains of NADPH oxidase target cell membranes via direct and indirect recruitment by phosphoinositides.

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The Phox homology (PX) domain, a new player in phosphoinositide signalling

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Identifiers

10.1074/JBC.M111.332874

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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