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The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
title
The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author
Christos Tsatsanis
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
C Patriotis
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
S E Bear
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
P N Tsichlis
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
language of work or name
English
0 references
publication date
1 March 1998
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
number of pages
6
1 reference
based on heuristic
inferred from page(s)
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
95
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
3827-3832
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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PubMed Central
reference URL
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NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
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Cot kinase regulation of IL-2 production in Jurkat T cells
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2 October 2017
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2 October 2017
Differential activation of transcription factors induced by Ca2+ response amplitude and duration
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Expression of NFAT-family proteins in normal human T cells
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Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation
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PubMed Central
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2 October 2017
Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3
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2 October 2017
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
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Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis
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2 October 2017
The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.
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2 October 2017
Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor
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2 October 2017
Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase
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PubMed Central
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2 October 2017
Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
CD28 and apoptosis
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2 October 2017
Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion.
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PubMed Central
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2 October 2017
Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Beta-galactosidase and chloramphenicol acetyltransferase assays in 96-well plates
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
NF-AT components define a family of transcription factors targeted in T-cell activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Signal transmission between the plasma membrane and nucleus of T lymphocytes
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PubMed Central
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2 October 2017
Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation
1 reference
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PubMed Central
reference URL
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2 October 2017
Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Transcriptional regulation of the IL-2 gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Characterization of antigen receptor response elements within the interleukin-2 enhancer
1 reference
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PubMed Central
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2 October 2017
Contingent genetic regulatory events in T lymphocyte activation
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PubMed Central
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2 October 2017
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin
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2 October 2017
Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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2 October 2017
Involvement of phosphatidylinositol 3-kinase in NFAT activation in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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11 July 2018
Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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11 July 2018
Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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11 July 2018
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19922
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11 July 2018
Identifiers
DOI
10.1073/PNAS.95.7.3827
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
ADS bibcode
1998PNAS...95.3827T
0 references
PMC publication ID
19922
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
9520452
1 reference
stated in
Europe PubMed Central
PMC publication ID
19922
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9520452%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
ResearchGate publication ID
51314509
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