(Q36021048)

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Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells

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15 February 2020

Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells (English)

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15 February 2020

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cannabinoid receptor

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Anna Maria Malfitano

7

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15 February 2020

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Elena Ciaglia

1

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15 February 2020

Giovanni Torelli

2

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15 February 2020

Simona Pisanti

3

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15 February 2020

Paola Picardi

4

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15 February 2020

Alba D'Alessandro

5

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15 February 2020

Chiara Laezza

6

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15 February 2020

Donatella Fiore

8

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15 February 2020

Antonio Christian Pagano Zottola

9

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15 February 2020

Maria Chiara Proto

10

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15 February 2020

Giuseppe Catapano

11

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15 February 2020

Patrizia Gazzerro

12

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15 February 2020

Maurizio Bifulco

13

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15 February 2020

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1 June 2015

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15 February 2020

1 reference

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15 February 2020

6

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15 February 2020

17

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15 February 2020

15464-15481

1 reference

Europe PubMed Central

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15 February 2020

Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.

1 reference

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2 October 2017

Cannabinoid receptor type 1 immunoreactivity and disease severity in human epithelial ovarian tumors.

1 reference

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2 October 2017

Transforming growth factor-beta and its implication in the malignancy of gliomas

1 reference

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2 October 2017

Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The endocannabinoid signaling system in cancer

1 reference

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2 October 2017

Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells.

1 reference

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2 October 2017

The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The CB1 receptor antagonist rimonabant controls cell viability and ascitic tumour growth in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Understanding glioblastoma tumor biology: the potential to improve current diagnosis and treatments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

PAX3-FOXO1 induces cannabinoid receptor 1 to enhance cell invasion and metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

High tumour cannabinoid CB1 receptor immunoreactivity negatively impacts disease-specific survival in stage II microsatellite stable colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Rimonabant-induced apoptosis in leukemia cell lines: activation of caspase-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The anticancer immune response: indispensable for therapeutic success?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Cannabinoids in pancreatic cancer: correlation with survival and pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Rimonabant: just an antiobesity drug? Current evidence on its pleiotropic effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Cannabinoid receptors in human astroglial tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Role of Stat3 in regulating p53 expression and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The endocannabinoid system drives neural progenitor proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

MICA/NKG2D-mediated immunogene therapy of experimental gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Immune escape of tumors: apoptosis resistance and tumor counterattack.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

2 October 2017

Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

1 reference

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2 October 2017

Alteration of endocannabinoid system in human gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

11 July 2018

The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

11 July 2018

Activation of the mas oncogene during transfection of monoblastic cell line DNA.

1 reference

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11 July 2018

N6-isopentenyladenosine affects cytotoxic activity and cytokines production by IL-2 activated NK cells and exerts topical anti-inflammatory activity in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

23 September 2018

Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

23 September 2018

N6-isopentenyladenosine, an endogenous isoprenoid end product, directly affects cytotoxic and regulatory functions of human NK cells through FDPS modulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

23 September 2018

Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

23 September 2018

Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.

1 reference

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23 September 2018

Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non-tumour brain tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4558164

23 September 2018

Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice

1 reference

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23 September 2018

Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity

1 reference

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23 September 2018

CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low levels of phosphorylated epidermal growth factor receptor in nonmalignant and malignant prostate tissue predict favorable outcome in prostate cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26008966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoid receptor 1 antagonism in hepatocellular carcinoma: killing two birds with one stone

1 reference

https://pubmed.ncbi.nlm.nih.gov/26008966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26008966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high cannabinoid CB(1) receptor immunoreactivity is associated with disease severity and outcome in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26008966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards the use of cannabinoids as antitumour agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/26008966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.3895

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26008966%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26008966%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26008966%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

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