(Q36025032)

11 August 2017

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title

Genetic alterations involved in the transition from well-differentiated to poorly differentiated and anaplastic thyroid carcinomas (English)

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11 August 2017

Yuri E Nikiforov

1

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11 August 2017

1 January 2004

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11 August 2017

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11 August 2017

15

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11 August 2017

4

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11 August 2017

319-327

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https://scigraph.springernature.com/pub.10.1385/ep:15:4:319

11 August 2017

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cites work

E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas.

1 reference

12 December 2020

Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

1 reference

12 December 2020

p53 gene mutation in thyroid carcinoma

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12 December 2020

p53 gene mutations associated with anaplastic transformation of human thyroid carcinomas

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12 December 2020

PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses

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12 December 2020

Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland

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12 December 2020

Absence of mutations in the beta-catenin and adenomatous polyposis coli genes in papillary and follicular thyroid carcinomas

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12 December 2020

RET/PTC rearrangement in thyroid tumors

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12 December 2020

Altered gene expression in immunogenic poorly differentiated thyroid carcinomas from RET/PTC3p53-/- mice

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12 December 2020

BRAF mutations in papillary carcinomas of the thyroid

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12 December 2020

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

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12 December 2020

Mutations of the BRAF gene in human cancer

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12 December 2020

N-ras mutation in poorly differentiated thyroid carcinomas: correlation with bone metastases and inverse correlation to thyroglobulin expression.

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12 December 2020

Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis

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12 December 2020

Reexpression of thyroid peroxidase in a derivative of an undifferentiated thyroid carcinoma cell line by introduction of wild-type p53.

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12 December 2020

p53 in a thyroid follicular carcinoma with foci of poorly differentiated and anaplastic carcinoma.

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12 December 2020

Expression of PAX8-PPAR gamma 1 rearrangements in both follicular thyroid carcinomas and adenomas

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12 December 2020

RET activation and clinicopathologic features in poorly differentiated thyroid tumors

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12 December 2020

RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes

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12 December 2020

Multistep carcinogenesis in anaplastic thyroid carcinoma: a case report

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12 December 2020

Genome-wide appraisal of thyroid cancer progression.

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12 December 2020

Molecular evidence of anaplastic transformation in coexisting well-differentiated and anaplastic carcinomas of the thyroid

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12 December 2020

Allelotyping of anaplastic thyroid carcinoma: frequent allelic losses on 1q, 9p, 11, 17, 19p, and 22q

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12 December 2020

Genetic Changes in Chromosomes 1p and 17p in Thyroid Cancer Progression.

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12 December 2020

p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells.

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12 December 2020

High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis

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12 December 2020

p53 mutations in all stages of thyroid carcinomas.

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12 December 2020

Prevalence of Ras mutations in thyroid neoplasia

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12 December 2020

Prevalence of activating ras mutations in morphologically characterized thyroid nodules.

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12 December 2020

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway

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12 December 2020

Genetic and biological subgroups of low-stage follicular thyroid cancer

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12 December 2020

Presence of mutations in all three ras genes in human thyroid tumors

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12 December 2020

Loss of p53 promotes anaplasia and local invasion in ret/PTC1-induced thyroid carcinomas

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12 December 2020

Ras oncogene mutations in benign and malignant thyroid neoplasms

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12 December 2020

PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]

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12 December 2020

Genetic alterations in thyroid tumor progression: association with p53 gene mutations.

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12 December 2020

Stepwise participation of p53 gene mutation during dedifferentiation of human thyroid carcinomas

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12 December 2020

Mutations of p53 in thyroid carcinoma with an insular component

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12 December 2020

Mutated human Kirsten ras, driven by a thyroglobulin promoter, induces a growth advantage and partially dedifferentiates rat thyroid epithelial cells in vitro.

1 reference

12 December 2020

Production of transgenic mice expressing the Ki-ras oncogene under the control of a thyroglobulin promoter

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12 December 2020

High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

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12 December 2020

Thyroid pathologies in transgenic mice expressing a human activated Ras gene driven by a thyroglobulin promoter

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12 December 2020

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

1 reference

12 December 2020

ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer.

1 reference

12 December 2020

Human N-ras, TRK-T1, and RET/PTC3 oncogenes, driven by a thyroglobulin promoter, differently affect the expression of differentiation markers and the proliferation of thyroid epithelial cells.

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12 December 2020

H-ras protooncogene mutations in human thyroid neoplasms

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12 December 2020

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

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12 December 2020

Molecular mechanisms of RET activation in human cancer.

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12 December 2020

High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines.

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12 December 2020

Role of ras mutation in the progression of thyroid carcinoma of follicular epithelial origin

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12 December 2020

In vitro models of thyroid cancer

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12 December 2020

Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors.

1 reference

12 December 2020

BRAF Mutation in Papillary Thyroid Carcinoma

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12 December 2020

Mutant thyroid hormone receptor beta represses the expression and transcriptional activity of peroxisome proliferator-activated receptor gamma during thyroid carcinogenesis

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12 December 2020

Poorly differentiated ("insular") thyroid carcinoma. A reinterpretation of Langhans' "wuchernde Struma"

1 reference

12 December 2020

DNA copy number changes in thyroid carcinoma

1 reference

12 December 2020

Studies of allelic loss in thyroid tumors reveal major differences in chromosomal instability between papillary and follicular carcinomas

1 reference

12 December 2020

Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas.

1 reference

12 December 2020

Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers

1 reference

12 December 2020

N-ras mutation: an independent prognostic factor for aggressiveness of papillary thyroid carcinoma

1 reference

12 December 2020

Defective E-cadherin/catenin complexes in human cancer

1 reference

12 December 2020

In vitro reconstruction of tumour initiation in a human epithelium.

1 reference

12 December 2020

RET oncogene activation in papillary thyroid carcinoma.

1 reference

12 December 2020

Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas

1 reference

12 December 2020

Identifiers

DOI

10.1385/EP:15:4:319

1 reference

PubMed ID

15681856

Dimensions Publication ID

11 August 2017

0 references

1 reference

PubMed ID

15681856