(Q36028027)

11 August 2017

The effect of 2-[(aminopropyl)amino] ethanethiol (WR-1065) on radiation induced DNA double strand damage and repair in V79 cells (English)

1 reference

11 August 2017

C P Sigdestad

1

1 reference

11 August 2017

S H Treacy

series ordinal

2

1 reference

11 August 2017

L A Knapp

series ordinal

3

1 reference

11 August 2017

D J Grdina

series ordinal

4

1 reference

11 August 2017

language of work or name

English

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publication date

1 May 1987

1 reference

British Journal of Cancer

11 August 2017

1 reference

11 August 2017

55

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11 August 2017

477-482

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11 August 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1038/bjc.1987.97

11 August 2017

0 references

cites work

A more general role for WR-2721 in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Toxicity of WR-2721 administered in single and multiple doses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

The effect of 2-[(aminopropyl)amino] ethanethiol (WR1065) on radiation-induced DNA damage and repair and cell progression in V79 cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Mechanisms of DNA repair and their potential modification for radiotherapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Distribution of 35 S-Labeled WR-2721 in Normal and Malignant Tissues of the Mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Radioprotection by WR-2721 in vitro at low oxygen tensions: Implications for its mechanisms of action

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

2-[(Aminopropyl)amino]ethanethiol (WR1065) is anti-neoplastic and anti-mutagenic when given during 60Co gamma-ray irradiation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Protection against cis-dichlorodiammine Pt (II) cytotoxicity in vitro by cysteamine.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

The role of WR-2721 in radiotherapy and/or chemotherapy

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001724

Differential chemoprotection of normal and malignant tissues

23 September 2018

1 reference

12 December 2020

Effect of thiourea on survival and DNA cross-link formation in cells treated with platinum(II) complexes, L-phenylalanine mustard, and bis(2-chloroethyl)methylamine

1 reference

12 December 2020

Phase I clinical studies with WR-2721

1 reference

12 December 2020

Thiourea prevents cytotoxicity and mutagenicity, but not sister-chromated exchanges in V79 cells treated with cis-diaminedichloroplatinum (II)

1 reference

12 December 2020

Interaction of Cultured Mammalian Cells with WR-2721 and Its Thiol, WR-1065: Implications for Mechanisms of Radioprotection

1 reference

12 December 2020

Variation in normal and tumor tissue sensitivity of mice to ionizing radiation-induced DNA strand breaks in vivo

1 reference

12 December 2020

An Effect of Elevated Postirradiation pH on the Yield of Double-Strand Breaks in DNA from Irradiated Bacterial Cells

1 reference

12 December 2020

Factors influencing the oxidation of cysteamine and other thiols: implications for hyperthermic sensitization and radiation protection

1 reference

12 December 2020

Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol

1 reference

12 December 2020

Clinical study of the radioprotective effects of Amifostine (YM-08310, WR-2721) on chronic radiation injury

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1987.97

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Dimensions Publication ID

11 August 2017

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1 reference

11 August 2017

1 reference