(Q36028610)

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Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading.

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27 December 2019

Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading (English)

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27 December 2019

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mesenchymal stem cell

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Carlos M. Isales

8

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27 December 2019

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M W Hamrick

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27 December 2019

X Shi

2

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27 December 2019

W Zhang

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27 December 2019

C Pennington

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27 December 2019

H Thakore

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27 December 2019

M Haque

6

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27 December 2019

B Kang

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27 December 2019

S Fulzele

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27 December 2019

K H Wenger

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27 December 2019

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publication date

23 February 2007

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27 December 2019

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27 December 2019

40

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27 December 2019

6

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27 December 2019

1544-1553

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27 December 2019

Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Myostatin mutation associated with gross muscle hypertrophy in a child

1 reference

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2 October 2017

The 'muscle-bone unit' during the pubertal growth spurt.

1 reference

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2 October 2017

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Increased bone mineral density in the femora of GDF8 knockout mice

1 reference

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2 October 2017

Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis.

1 reference

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2 October 2017

Induction of cachexia in mice by systemically administered myostatin.

1 reference

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2 October 2017

Transforming growth factor beta2 inhibits adipocyte differentiation induced by skeletal unloading in rat bone marrow stroma

1 reference

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2 October 2017

Decreased bone density in ambulatory patients with duchenne muscular dystrophy

1 reference

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2 October 2017

Skeletal alterations in rats during space flight

1 reference

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2 October 2017

Inhibition of preadipocyte differentiation by myostatin treatment in 3T3-L1 cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Expression and localization of activin receptors during endochondral bone development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Is there a therapeutic opportunity to either prevent or treat osteopenic disorders by inhibiting marrow adipogenesis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Double muscling in cattle due to mutations in the myostatin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Influence of muscle strength on bone strength during childhood and adolescence

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Regional muscle loss after short duration spaceflight.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Quantitative histological data on disuse osteoporosis: comparison with biological data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Atrophy of the soleus muscle by hindlimb unweighting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

2 October 2017

Fluid flow stimulates expression of osteopontin and bone sialoprotein by bone marrow stromal cells in a temporally dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

11 July 2018

Muscle strength, bone mass, and age-related bone loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

11 July 2018

Relationship between limb and muscle blood flow in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

11 July 2018

Relation between bone mass and muscle weight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

11 July 2018

Relationships between marrow fat and bone turnover in ovariectomized and intact rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

11 July 2018

Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF‐8 (myostatin)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Fluid pressure gradients, arising from oscillations in intramedullary pressure, is correlated with the formation of bone and inhibition of intracortical porosity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Troglitazone treatment increases bone marrow adipose tissue volume but does not affect trabecular bone volume in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Modulation of myostatin expression during modified muscle use.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Osteoblasts express types I and II activin receptors during early intramembranous and endochondral bone formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Genetic lineage, bone mass, and physical activity in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001954

23 September 2018

Age-related loss of muscle mass and bone strength in mice is associated with a decline in physical activity and serum leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum myostatin-immunoreactive protein is increased in 60-92 year old women and men with muscle wasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myostatin-deficient mice lose more skeletal muscle mass than wild-type controls during hindlimb suspension

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle strength as a predictor of bone mineral density in young women

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoblast progenitor fate and age-related bone loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histochemical profiles of fast fiber types IIB, IID, and IIA in skeletal muscles of mouse, rat, and rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat Hindlimb Unloading by Tail Suspension Reduces Osteoblast Differentiation, Induces IL-6 Secretion, and Increases Bone Resorption in Ex Vivo Cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Increased Muscle Mass on Bone in Male Mice Overexpressing IGF-I in Skeletal Muscles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonate effects in rat unloaded hindlimb bone loss model: three-dimensional microcomputed tomographic, histomorphometric, and densitometric analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between quadriceps strength and bone mineral density of the proximal tibia and distal forearm in women

1 reference

https://pubmed.ncbi.nlm.nih.gov/17383950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BONE.2007.02.012

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27 December 2019

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27 December 2019

PubMed publication ID

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Europe PubMed Central

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27 December 2019

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