(Q36037916)

11 August 2017

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title

Early origins of obesity: programming the appetite regulatory system (English)

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11 August 2017

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1 reference

I Caroline McMillen

1

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11 August 2017

Clare L Adam

series ordinal

2

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11 August 2017

Beverly S Mühlhäusler

series ordinal

3

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11 August 2017

language of work or name

English

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publication date

10 February 2005

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11 August 2017

published in

Journal of Physiology

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11 August 2017

volume

565

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11 August 2017

issue

Pt 1

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11 August 2017

page(s)

9-17

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Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation

11 August 2017

cites work

1 reference

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23 September 2018

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Developmental programming of the metabolic syndrome by maternal nutritional imbalance: how strong is the evidence from experimental models in mammals?

23 September 2018

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Prenatal programming of postnatal obesity: fetal nutrition and the regulation of leptin synthesis and secretion before birth.

23 September 2018

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Appetite regulatory neuropeptides are expressed in the sheep hypothalamus before birth.

23 September 2018

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Trophic action of leptin on hypothalamic neurons that regulate feeding

23 September 2018

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Neuroscience. The fat-brain axis enters a new dimension

23 September 2018

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Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice.

23 September 2018

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Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism

23 September 2018

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Brown adipose tissue: function and physiological significance

23 September 2018

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Determinants of fetal leptin synthesis, fat mass, and circulating leptin concentrations in well-nourished ewes in late pregnancy.

23 September 2018

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Altered responses to orexigenic (AGRP, MCH) and anorexigenic (alpha-MSH, CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats

23 September 2018

1 reference

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For debate: Fetal and early postnatal growth restriction lead to diabetes, the metabolic syndrome and renal failure.

23 September 2018

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Ontogeny of the hypothalamic neuropeptide Y system

23 September 2018

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Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids

23 September 2018

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Programming of lean body mass: a link between birth weight, obesity, and cardiovascular disease?

23 September 2018

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Prevalence and trends in overweight among US children and adolescents, 1999-2000

23 September 2018

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Prevalence and Trends in Obesity Among US Adults, 1999-2000

23 September 2018

1 reference

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Leptin receptor expression in the rat placenta: changes in ob-ra, ob-rb, and ob-re with gestational age and suppression by glucocorticoids

23 September 2018

1 reference

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Hypothalamic ventromedial and arcuate neurons of normal and postnatally overnourished rats differ in their responses to melanin-concentrating hormone

23 September 2018

1 reference

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Increased inhibition by agouti-related peptide of ventromedial hypothalamic neurons in rats overweight due to early postnatal overfeeding

23 September 2018

1 reference

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Circulating leptin concentrations are positively related to leptin messenger RNA expression in the adipose tissue of fetal sheep in the pregnant ewe fed at or below maintenance energy requirements during late gestation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Fetal leptin is a signal of fat mass independent of maternal nutrition in ewes fed at or above maintenance energy requirements

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Spatial and developmental regulation of leptin in fetal sheep

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Hypothalamic gene expression in sheep for cocaine- and amphetamine-regulated transcript, pro-opiomelanocortin, neuropeptide Y, agouti-related peptide and leptin receptor and responses to negative energy balance

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Organization of human hypothalamus in fetal development

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Birth weight and body composition in young women: a prospective twin study

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Ontogeny and insulin regulation of fetal ovine white adipose tissue leptin expression

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Brain pathways controlling food intake and body weight.

23 September 2018

1 reference

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Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study

23 September 2018

1 reference

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Inhibition by insulin of hypothalamic VMN neurons in rats overweight due to postnatal overfeeding

23 September 2018

1 reference

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Adipose tissue as an endocrine organ

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Decreased inhibition by leptin of hypothalamic arcuate neurons in neonatally overfed young rats.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition.

23 September 2018

1 reference

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Abundance of leptin mRNA in fetal adipose tissue is related to fetal body weight

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Elevation of hypothalamic neuropeptide Y-neurons in adult offspring of diabetic mother rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Increased response to NPY of hypothalamic VMN neurons in postnatally overfed juvenile rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Observations on the orexigenic hypothalamic neuropeptide Y-system in neonatally overfed weanling rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Perinatal elevation of hypothalamic insulin, acquired malformation of hypothalamic galaninergic neurons, and syndrome x-like alterations in adulthood of neonatally overfed rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

High serum leptin concentrations during catch-up growth of children born with intrauterine growth retardation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Gestational diabetes: risk or myth?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Leptin receptor and neuropeptide Y gene expression in the sheep brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Birth weight, adulthood BMI, and subsequent weight gain in relation to leptin levels in Swedish women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Malformations of hypothalamic nuclei in hyperinsulinemic offspring of rats with gestational diabetes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Concentrations of leptin in the serum of pregnant, lactating, and cycling rats and of leptin messenger ribonucleic acid in rat placental tissue.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Hypothalamic insulin and neuropeptide Y in the offspring of gestational diabetic mother rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Intrauterine nutrition: its importance during critical periods for cardiovascular and endocrine development

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Leptin and the regulation of body weight in mammals

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Effects of birth weight and postnatal nutrition on neonatal sheep: I. Body growth and composition, and some aspects of energetic efficiency

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Syndrome X-like alterations in adult female rats due to neonatal insulin treatment

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Familial predisposition for obesity may modify the predictive value of serum leptin concentrations for long-term weight change in obese women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Strategies and potential molecular targets for obesity treatment

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Ontogeny of leptin in human fetuses and newborns: effect of intrauterine growth retardation on serum leptin concentrations

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Increased plasma leptin levels are associated with fat accumulation in Japanese Americans.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic neuropeptide Y expression in the sheep fetus

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Neonatal cord blood leptin: its relationship to birth weight, body mass index, maternal diabetes, and steroids

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

The placenta is not the main source of leptin production in pregnant rat: gestational profile of leptin in plasma and adipose tissues.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Serum leptin concentration in cord blood: relationship to birth weight and gender

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

The Thrifty Phenotype hypothesis: how does it look after 5 years?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Birth weight and adult hypertension, diabetes mellitus, and obesity in US men.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Maternal insulin manipulations in rats organize body weight and noradrenergic innervation of the hypothalamus in gonadally intact male offspring

23 September 2018

1 reference

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Birth weight and adult hypertension and obesity in women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Birth weight and its relationship to size attained and relative fat distribution at 7 to 12 years of age.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Leptin receptors expressed on pancreatic beta-cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Maternal hormonal manipulations in rats cause obesity and increase medial hypothalamic norepinephrine release in male offspring

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Intrauterine food restriction is associated with obesity in young rats.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Perinatal hyperinsulinism as possible predisposing factor for diabetes mellitus, obesity and enhanced cardiovascular risk in later life

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Fetal and infant growth and cardiovascular risk factors in women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Ontogeny of a novel peptide, neuropeptide Y (NPY) in rat brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Gestational undernutrition and the development of obesity in rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Immunohistochemical analysis of the early ontogeny of the neuropeptide Y system in rat brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Banting lecture 1988. Role of insulin resistance in human disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Maternal hyperglycemia in pregnant rats: its effect on growth and carbohydrate metabolism in the offspring.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Long-Term Prospective Evaluation of Offspring of Diabetic Mothers

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Early growth and abdominal fatness in adult life

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Obesity and enhanced diabetes and cardiovascular risk in adult rats due to early postnatal overfeeding

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Obesity in young men after famine exposure in utero and early infancy

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Early nutrition and leptin concentrations in later life

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464497

Evidence that the amount of food consumed in early life fixes appetite in the rat

21 October 2018

1 reference

12 December 2020

Growth and the development of dietary obesity in adulthood of rats which have been undernourished during development

1 reference

12 December 2020

Obesity and adipocyte abnormalities in offspring of rats undernourished during pregnancy

1 reference

12 December 2020

The effect of diet on food intake and adiposity in rats made obese by gestational undernutrition

1 reference

12 December 2020

Overweight and increased diabetes susceptibility in neonatally insulin-treated adult rats

1 reference

12 December 2020

Alterations in fetal adipose tissue leptin expression correlate with the development of adipose tissue

1 reference

12 December 2020

Fetal plasma leptin concentrations: relationship with different intrauterine growth patterns from 19 weeks to term

1 reference

12 December 2020

Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome

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12 December 2020

Leptin concentrations are elevated in newborn infants of diabetic mothers

1 reference

12 December 2020

Birth weight and body composition in young adult men—a prospective twin study

1 reference

12 December 2020

Insulin sensitivity in adult female rats subjected to malnutrition during the perinatal period

1 reference

12 December 2020

The epidemiology of obesity

1 reference

12 December 2020

Development of the neuronal system containing neuropeptide Y in the rat hypothalamus

1 reference

12 December 2020

Size at birth and plasma leptin concentrations in adult life

1 reference

12 December 2020

Impaired transport of leptin across the blood-brain barrier in obesity

1 reference

12 December 2020

Hypothalamic neuropeptide Y levels in weaning offspring of low-protein malnourished mother rats

1 reference

12 December 2020

Impact of birth weight on ethnic variations in subcutaneous and central adiposity in American children aged 5-11 years. A study from the Third National Health and Nutrition Examination Survey

1 reference

12 December 2020

Parental and perinatal factors associated with childhood obesity in north-east Italy

1 reference

12 December 2020

Leptin concentration in cord blood correlates with intrauterine growth

1 reference

12 December 2020

Leptin alters the structural and functional characteristics of adipose tissue before birth

1 reference

12 December 2020

10.1113/JPHYSIOL.2004.081992

Identifiers

DOI

1 reference

11 August 2017

0 references

1 reference