(Q36043701)

11 August 2017

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title

Analysis of genotoxicity and the carcinogenic mode of action for ortho-phenylphenol (English)

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11 August 2017

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David Brusick

1

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11 August 2017

publication date

1 June 2005

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Environmental and Molecular Mutagenesis

11 August 2017

published in

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11 August 2017

volume

45

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11 August 2017

issue

5

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11 August 2017

page(s)

460-481

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Evaluation of hyperdiploidy in the bladder epithelial cells of male F344 rats treated with ortho-phenylphenol

11 August 2017

cites work

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International Commission for Protection Against Environmental Mutagens and Carcinogens. A method for combining and comparing short-term genotoxicity test data: preface. A report from ICPEMC Committee 1

21 January 2018

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An assessment of the genetic toxicity of atrazine: relevance to human health and environmental effects.

21 January 2018

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Oxidative damage to DNA in mammalian chromatin

21 January 2018

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A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures

21 January 2018

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Aroclor-1254-induced rat-liver S9 causes chromosomal aberrations in CHO cells but not human lymphocytes: a role for active oxygen?

21 January 2018

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International Commission for Protection Against Environmental Mutagens and Carcinogens. A method for comparing and combining short-term genotoxicity test data: results and interpretation

21 January 2018

1 reference

In vivo genotoxicity of sodium ortho-phenylphenol: phenylbenzoquinone is one of the DNA-binding metabolite(s) of sodium ortho-phenylphenol.

21 January 2018

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In vivo genotoxicity of ortho-phenylphenol, biphenyl, and thiabendazole detected in multiple mouse organs by the alkaline single cell gel electrophoresis assay

21 January 2018

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Detection of deletion mutations in pSV2gpt-transformed cells

21 January 2018

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Clastogenicity in vitro of the Na, K, Ca and Mg salts of saccharin; and of magnesium chloride; consideration of significance

21 January 2018

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7 January 2021

Detection of micronuclei, cell proliferation and hyperdiploidy in bladder epithelial cells of rats treated with o-phenylphenol

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7 January 2021

O-phenylphenol and its sodium and potassium salts: a toxicological assessment

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7 January 2021

Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations.

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7 January 2021

A proposed method for assembly and interpretation of short-term test data

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7 January 2021

Studies of oncogene activation and tumor suppressor gene inactivation in normal and neoplastic rodent tissue

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7 January 2021

Guide for the Salmonella typhimurium/mammalian microsome tests for bacterial mutagenicity.

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7 January 2021

Cytotoxicity and chromosome aberrations in vitro: experience in industry and the case for an upper limit on toxicity in the aberration assay

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7 January 2021

32P-postlabelling method as a sensitive indicator for analysis of genotoxicity of biphenyl derivatives

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7 January 2021

Long-term toxicity and carcinogenicity study of sodium o-phenylphenate in B6C3F1 mice

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7 January 2021

Clastogenic activity of caffeic acid and its relationship to hydrogen peroxide generated during autooxidation

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7 January 2021

The ability of the Comet assay to discriminate between genotoxins and cytotoxins

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7 January 2021

Metabolites of the biocide o-phenylphenol generate oxidative DNA lesions in V 79 cells.

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7 January 2021

Induction of tumours of the urinary system in F344 rats by dietary administration of sodium o-phenylphenate

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7 January 2021

Induction of tumours of the urinary bladder in F344 rats by dietary administration of o-phenylphenol

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7 January 2021

Peroxidative activation of o-phenylhydroquinone leads to the formation of DNA adducts in HL-60 cells

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7 January 2021

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

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7 January 2021

Dose-dependent binding of ortho-phenylphenol to protein but not DNA in the urinary bladder of male F344 rats

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7 January 2021

Genotoxic effects of the o-phenylphenol metabolites phenylhydroquinone and phenylbenzoquinone in V79 cells

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7 January 2021

Correlation between the DNA damage in urinary bladder epithelium and the urinary 2-phenyl-1,4-benzoquinone levels from F344 rats fed sodium o-phenylphenate in the diet

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7 January 2021

DNA damage in forestomach epithelium from male F344 rats following oral administration of tert-butylquinone, one of the forestomach metabolites of 3-BHA

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7 January 2021

Further mutagenicity studies on pesticides in bacterial reversion assay systems

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7 January 2021

Analysis of mitotic nondisjunction with Aspergillus nidulans

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7 January 2021

Oxidative damage to cellular and isolated DNA by metabolites of a fungicide ortho-phenylphenol

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7 January 2021

DNA cleavage by phenylhydroquinone: the major metabolite of a fungicide o-phenylphenol

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7 January 2021

Formation of 8-hydroxydeoxyguanosine in calf thymus DNA treated in vitro with phenylhydroquinone, the major metabolite of O-phenylphenol.

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7 January 2021

Induction of 8-hydroxy-2'-deoxyguanosine in CHO-K1 cells exposed to phenyl-hydroquinone, a metabolite of ortho-phenylphenol

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7 January 2021

Dose- and time-response studies of sodium o-phenylphenate urinary bladder carcinogenicity in rats

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7 January 2021

The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix

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7 January 2021

Examination of microsomal cytochrome P450-catalyzed in vitro activation of o-phenylphenol to DNA binding metabolite(s) by 32P-postlabeling technique

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7 January 2021

Methods of DNA adduct determination and their application to testing compounds for genotoxicity

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7 January 2021

Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: a comparison with bacterial mutagenicity using 218 compounds.

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7 January 2021

Molecular mechanisms involved in the toxicity of orthophenylphenol and its sodium salt

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7 January 2021

Changes in urine composition, bladder epithelial morphology, and DNA synthesis in male F344 rats in response to ingestion of bladder tumor promoters

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7 January 2021

Urinary physiologic and chemical metabolic effects on the urothelial cytotoxicity and potential DNA adducts of o-phenylphenol in male rats.

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7 January 2021

The beneficial and hazardous effects of simple phenolic compounds

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7 January 2021

Sister-chromatid exchanges in association with occupational exposure to ethylene oxide

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7 January 2021

Orthophenylphenol mutagenicity in a human cell strain

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7 January 2021

Sodium o-phenylphenate (OPP-Na) promotes skin carcinogenesis in CD-1 female mice initiated with 7,12-dimethylbenz[a]anthracene

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7 January 2021

Genotoxic effects of o-phenylphenol metabolites in CHO-K1 cells

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7 January 2021

Sulfhydryl compounds inhibit the cyto- and geno-toxicity of o-phenylphenol metabolites in CHO-K1 cells

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7 January 2021

Effect of scavengers of active oxygen species on cell damage caused in CHO-K1 cells by phenylhydroquinone, an o-phenylphenol metabolite

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7 January 2021

Induction of chromosome aberrations and sister-chromatid exchanges in CHO-K1 cells by o-phenylphenol

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7 January 2021

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

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7 January 2021

DNA adduct formation by o-phenylphenol metabolite in vivo and in vitro

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7 January 2021

Chemical mutagenesis testing in Drosophila. V. Results of 53 coded compounds tested for the National Toxicology Program

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7 January 2021

Identifiers

DOI

10.1002/EM.20116

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11 August 2017

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