(Q36052545)

English

Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

N-retinylidene-N-retinylethanolamine

1 reference

ChEBI release 2020-05-28

author name string

Nicholas P Boyer

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Daniel Higbee

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Mark B Currin

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lorie R Blakeley

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Chunhe Chen

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Zsolt Ablonczy

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Rosalie K Crouch

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Yiannis Koutalos

8

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

8 May 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

26

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

22276-22286

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lipofuscin and A2E accumulate with age in the retinal pigment epithelium of Nrl-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Spatial localization of A2E in the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Mass spectrometry provides accurate and sensitive quantitation of A2E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Rapid formation of all-trans retinol after bleaching in frog and mouse rod photoreceptor outer segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Photooxidation of RPE lipofuscin bisretinoids enhances fluorescence intensity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Phospholipid meets all-trans-retinal: the making of RPE bisretinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Formation of all-trans retinol after visual pigment bleaching in mouse photoreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Retinal pigment epithelium lipofuscin proteomics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

RPE lipofuscin and its role in retinal pathobiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

The human ATP-binding cassette (ABC) transporter superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Vertebrate photoreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Oxidative damage and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Characterization of phospholipase D activity in bovine photoreceptor membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Blue light-induced singlet oxygen generation by retinal lipofuscin in non-polar media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

The renewal of photoreceptor cell outer segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Participation of the retinal pigment epithelium in the rod outer segment renewal process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Influence of early photoreceptor degeneration on lipofuscin in the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

Retinal light damage reduces autofluorescent pigment deposition in the retinal pigment epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

2 October 2017

What is lipofuscin? Defining characteristics and differentiation from other autofluorescent lysosomal storage bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

11 July 2018

Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

23 September 2018

N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

23 September 2018

Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

23 September 2018

Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

23 September 2018

The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

23 September 2018

The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381188

23 September 2018

Allelic variation in ABCR associated with Stargardt disease but not age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.329235

21 January 2018

Retinal age pigments generated by self-assembling lysosomotropic detergents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.329235

21 January 2018

Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo measurement of lipofuscin in Stargardt's disease--Fundus flavimaculatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of lipofuscin-like fluorophores by reaction of retinal with photoreceptor outer segments and liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circadian nature of rod outer segment disc shedding in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipofuscin and melanin of human retinal pigment epithelium. Fluorescence, enzyme cytochemical, and ultrastructural studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.329235

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36052545&oldid=1623557424"