(Q36053116)

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Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

based on heuristic

inferred from title

author name string

D Lebrecht

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

A Geist

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

U-P Ketelsen

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

J Haberstroh

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

B Setzer

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

U A Walker

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

21 May 2007

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

151

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

771-778

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Peroxynitrite: just an oxidative/nitrosative stressor or a physiological regulator as well?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Nitrosative stress and pharmacological modulation of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Time-Dependent and Tissue-Specific Accumulation of mtDNA and Respiratory Chain Defects in Chronic Doxorubicin Cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Assessment of precision and concordance of quantitative mitochondrial DNA assays: a collaborative international quality assurance study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Dexrazoxane does not protect against doxorubicin-induced damage in young rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

The mitochondrial DNA polymerase as a target of oxidative damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Dexrazoxane pre-treatment protects skinned rat cardiac trabeculae against delayed doxorubicin-induced impairment of crossbridge kinetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Structure of the adriamycin-cardiolipin complex. Role in mitochondrial toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

ICRF-187 permits longer treatment with doxorubicin in women with breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

2 October 2017

Long-lasting effect of dexrazoxane against anthracycline cardiotoxicity in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

27 July 2018

Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

27 July 2018

A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

27 July 2018

Inhibition and inactivation of NADH-cytochrome c reductase activity of bovine heart submitochondrial particles by the iron(III)-adriamycin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

27 July 2018

Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

Transcriptional analysis of doxorubicin-induced cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

Dexrazoxane (ICRF-187) Protects Cardiac Myocytes Against Doxorubicin by Preventing Damage to Mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

The doxorubicin-cardioprotective drug dexrazoxane undergoes metabolism in the rat to its metal ion-chelating form ADR-925.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

A new mtDNA mutation in the tRNA(Leu(UUR)) gene associated with maternally inherited cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014121

23 September 2018

Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the stability and cellular distribution of dioxopiperazines in cultured BHK-21S cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of adriamycin uptake in chick embryo heart and liver cells an murine L5178Y lymphoblasts in vitro: role of drug uptake in cardiotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive increase of the mutated mitochondrial DNA fraction in Kearns-Sayre syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxemia is associated with mitochondrial DNA damage and gene induction. Implications for cardiac disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin-induced cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of epidural cooling on lipid peroxidation after experimental spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/17519947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0707294

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

release_funntz33rnhg3afx6wyq2okfdq

1 reference

https://api.fatcat.wiki/v0/release/funntz33rnhg3afx6wyq2okfdq

24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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