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Characterization of follistatin-type domains and their contribution to myostatin and activin A antagonism.
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Europe PubMed Central
PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
title
Characterization of follistatin-type domains and their contribution to myostatin and activin A antagonism
(English)
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Europe PubMed Central
PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
author
Thomas B. Thompson
series ordinal
4
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Europe PubMed Central
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3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
author name string
Jennifer N Cash
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1
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Europe PubMed Central
PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Elizabeth B Angerman
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2
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Europe PubMed Central
PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Henry T Keutmann
series ordinal
3
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PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
publication date
16 May 2012
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3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
published in
Molecular Endocrinology
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stated in
Europe PubMed Central
PMCID
3385792
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
volume
26
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Europe PubMed Central
PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
issue
7
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PMCID
3385792
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1 February 2020
page(s)
1167-1178
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Europe PubMed Central
PMCID
3385792
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
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Follistatin and follistatin like-3 differentially regulate adiposity and glucose homeostasis
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TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs
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The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
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Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity
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The Structure of FSTL3·Activin A Complex DIFFERENTIAL BINDING OF N-TERMINAL DOMAINS INFLUENCES FOLLISTATIN-TYPE ANTAGONIST SPECIFICITY
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Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin
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Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
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Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding
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Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice
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Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development
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2 October 2017
Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions
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A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor
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FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults
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Biological activity of follistatin isoforms and follistatin-like-3 is dependent on differential cell surface binding and specificity for activin, myostatin, and bone morphogenetic proteins
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2 October 2017
Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities
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2 October 2017
Structural basis for the inhibition of activin signalling by follistatin.
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2 October 2017
The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding
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2 October 2017
Regulation of muscle mass by myostatin
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2 October 2017
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The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
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2 October 2017
Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
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2 October 2017
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2 October 2017
Evolutionary trace analysis of TGF-beta and related growth factors: implications for site-directed mutagenesis.
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2 October 2017
Crystal structure of the BMP-2-BRIA ectodomain complex
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2 October 2017
Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo
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2 October 2017
FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders
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2 October 2017
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
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2 October 2017
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
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2 October 2017
Multiple defects and perinatal death in mice deficient in follistatin
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2 October 2017
Different phenotypes for mice deficient in either activins or activin receptor type II
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2 October 2017
Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone
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2 October 2017
A novel role of follistatin, an activin-binding protein, in the inhibition of activin action in rat pituitary cells. Endocytotic degradation of activin and its acceleration by follistatin associated with cell-surface heparan sulfate
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11 July 2018
Characterization of unique binding kinetics of follistatin and activin or inhibin in serum.
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11 July 2018
Activin-binding protein from rat ovary is follistatin.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385792
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11 July 2018
Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis.
1 reference
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23 September 2018
The Role of Follistatin Domains in Follistatin Biological Action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385792
retrieved
23 September 2018
Cooperativity of binding epitopes and receptor chains in the BMP/TGFbeta superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385792
retrieved
23 September 2018
Follistatin: essential role for the N-terminal domain in activin binding and neutralization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385792
retrieved
23 September 2018
Identifiers
DOI
10.1210/ME.2012-1061
1 reference
stated in
Europe PubMed Central
PMCID
3385792
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMCID
3385792
1 reference
stated in
Europe PubMed Central
PMCID
3385792
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed ID
22593183
1 reference
stated in
Europe PubMed Central
PMCID
3385792
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22593183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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