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Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis.
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stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
title
Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
main subject
Drosophila
0 references
Sex lethal Dmel_CG43770
1 reference
stated in
GOA release 2020-03-11
stem cell differentiation
1 reference
based on heuristic
inferred from title
cell differentiation
1 reference
based on heuristic
inferred from title
author
Helen K. Salz
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
author name string
Johnnie Chau
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Laura Shapiro Kulnane
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
language of work or name
English
0 references
publication date
29 May 2012
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
number of pages
6
1 reference
based on heuristic
inferred from page(s)
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
volume
109
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
page(s)
9465-9470
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
issue
24
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
cites work
Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation.
1 reference
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PubMed Central
reference URL
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Sex determination in insects: a binary decision based on alternative splicing.
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2 October 2017
Brat promotes stem cell differentiation via control of a bistable switch that restricts BMP signaling
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PubMed Central
reference URL
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2 October 2017
Cell adhesion in regulation of asymmetric stem cell division
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PubMed Central
reference URL
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2 October 2017
Hrp48 attenuates Sxl expression to allow for proper notch expression and signaling in wing development
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PubMed Central
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2 October 2017
PPS, a large multidomain protein, functions with sex-lethal to regulate alternative splicing in Drosophila
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PubMed Central
reference URL
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2 October 2017
Sex determination in Drosophila: The view from the top.
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2 October 2017
eIF4A controls germline stem cell self-renewal by directly inhibiting BAM function in the Drosophila ovary
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Sex-lethal facilitates the transition from germline stem cell to committed daughter cell in the Drosophila ovary.
1 reference
stated in
PubMed Central
reference URL
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2 October 2017
Stem cell aging is controlled both intrinsically and extrinsically in the Drosophila ovary
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Genome-wide identification of alternatively spliced mRNA targets of specific RNA-binding proteins
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PubMed Central
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2 October 2017
The master switch gene sex-lethal promotes female development by negatively regulating the N-signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Drosophila Sex-lethal protein mediates polyadenylation switching in the female germline
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
How different is Venus from Mars? The genetics of germ-line stem cells in Drosophila females and males
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Germ line stem cell differentiation in Drosophila requires gap junctions and proceeds via an intermediate state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Dpp Signaling Silences bam Transcription Directly to Establish Asymmetric Divisions of Germline Stem Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
An empty Drosophila stem cell niche reactivates the proliferation of ectopic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Functional analysis of SNF, the Drosophila U1A/U2B" homolog: identification of dispensable and indispensable motifs for both snRNP assembly and function in vivo
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
RNA binding by Sxl proteins in vitro and in vivo
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Normal female germ cell differentiation requires the female X chromosome to autosome ratio and expression of sex-lethal in Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Functional changes associated with structural alterations induced by mobilization of a P element inserted in the Sex-lethal gene of Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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2 October 2017
Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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27 July 2018
Induction of female Sex-lethal RNA splicing in male germ cells: implications for Drosophila germline sex determination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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27 July 2018
Mutations affecting dosage compensation in Drosophila melanogaster: effects in the germline.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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27 July 2018
bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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27 July 2018
The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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27 July 2018
Is sex determination in germ line and soma controlled by separate genetic mechanisms?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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27 July 2018
Drosophila Sex lethal gene initiates female development in germline progenitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Males and females: creating differences while maintaining the similarities.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
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23 September 2018
Gene circuitry controlling a stem cell niche.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Germline stem cell number in the Drosophila ovary is regulated by redundant mechanisms that control Dpp signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Nanos maintains germline stem cell self-renewal by preventing differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Sex-lethal splicing autoregulation in vivo: interactions between SEX-LETHAL, the U1 snRNP and U2AF underlie male exon skipping.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
A host parasite interaction rescues Drosophila oogenesis defects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Nanos interacts with cup in the female germline of Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Ectopic expression of the Drosophila Bam protein eliminates oogenic germline stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Expression of the Sex-lethal gene is controlled at multiple levels during Drosophila oogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386055
retrieved
23 September 2018
Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22645327
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.1120473109
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ADS bibcode
2012PNAS..109.9465C
0 references
PMCID
3386055
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PubMed ID
22645327
1 reference
stated in
Europe PubMed Central
PMCID
3386055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22645327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ResearchGate publication ID
225074434
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