(Q36068444)

12 August 2017

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title

Tissue-specific dysregulation of 11beta-hydroxysteroid dehydrogenase type 1 and pathogenesis of the metabolic syndrome (English)

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12 August 2017

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Putignano P

1

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12 August 2017

Pecori Giraldi F

series ordinal

2

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12 August 2017

Cavagnini F

series ordinal

3

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12 August 2017

1 November 2004

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Journal of Endocrinological Investigation

12 August 2017

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12 August 2017

27

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12 August 2017

10

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12 August 2017

969-974

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https://scigraph.springernature.com/pub.10.1007/bf03347544

12 August 2017

0 references

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A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels

21 January 2018

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Type 1 11beta -hydroxysteroid dehydrogenase mediates glucocorticoid activation and insulin release in pancreatic islets

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PPARalpha agonists reduce 11beta-hydroxysteroid dehydrogenase type 1 in the liver.

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Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta -hydroxysteroid dehydrogenase type 1 expression and activity

21 January 2018

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Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.

21 January 2018

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Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle.

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Increased urinary free cortisol: a potential intermediate phenotype of essential hypertension.

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Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice

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Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice

21 January 2018

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11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

21 January 2018

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Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice

21 January 2018

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Assessing systemic 11beta-hydroxysteroid dehydrogenase with serum cortisone/cortisol ratios in healthy subjects and patients with diabetes mellitus and chronic renal failure

21 January 2018

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Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.

21 January 2018

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Glucocorticoid metabolism and the Metabolic Syndrome: associations in an elderly cohort

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21 January 2018

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Increased glucocorticoid receptor expression in human skeletal muscle cells may contribute to the pathogenesis of the metabolic syndrome

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12 December 2020

Role of glucocorticoids and fatty acids in the impairment of lipid metabolism observed in the metabolic syndrome

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12 December 2020

Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11beta-HSD-1-deficient mice

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12 December 2020

Increased urinary albumin excretion in Cushing's syndrome: remission after correction of hypercortisolaemia.

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12 December 2020

Hyperandrogenism in polycystic ovary syndrome. Evidence of dysregulation of 11 beta-hydroxysteroid dehydrogenase

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12 December 2020

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

1 reference

12 December 2020

A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo.

1 reference

12 December 2020

Regulation of glucocorticoid receptor alpha and beta isoforms and type I 11beta-hydroxysteroid dehydrogenase expression in human skeletal muscle cells: a key role in the pathogenesis of insulin resistance?

1 reference

12 December 2020

Elevated plasma cortisol concentrations: a link between low birth weight and the insulin resistance syndrome?

1 reference

12 December 2020

Altered control of cortisol secretion in adult men with low birth weight and cardiovascular risk factors

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12 December 2020

Differentiation of adipose stromal cells: the roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase

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12 December 2020

Distinguishing the activities of 11beta-hydroxysteroid dehydrogenases in vivo using isotopically labeled cortisol

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12 December 2020

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12 December 2020

Lack of relationship between 11beta-hydroxysteroid dehydrogenase setpoint and insulin sensitivity in the basal state and after 24h of insulin infusion in healthy subjects and type 2 diabetic patients

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12 December 2020

Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity

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12 December 2020

Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats

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12 December 2020

Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines

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12 December 2020

Cortisol metabolism in human obesity: impaired cortisone-->cortisol conversion in subjects with central adiposity

1 reference

12 December 2020

Absence of Cushingoid phenotype in a patient with Cushing's disease due to defective cortisone to cortisol conversion

1 reference

12 December 2020

Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action

1 reference

12 December 2020

Expression of the mRNA coding for 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: an in situ hybridization study

1 reference

12 December 2020

Cortisol and hypertension.

1 reference

12 December 2020

Increased glucocorticoid activity in men with cardiovascular risk factors

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03347544

1 reference

release_7u6uci4swjhilaubqvnqqhdd5i

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7u6uci4swjhilaubqvnqqhdd5i

24 November 2022

mapped directly with Wikidata item

1 reference