(Q36068686)

12 August 2017

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title

Ocular pharmacokinetics and safety of ciclosporin, a novel topical treatment for dry eye. (English)

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12 August 2017

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Diane D-S Tang-Liu

1

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12 August 2017

Andrew Acheampong

series ordinal

2

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12 August 2017

publication date

1 January 2005

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Clinical Pharmacokinetics

12 August 2017

published in

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12 August 2017

volume

44

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12 August 2017

issue

3

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12 August 2017

page(s)

247-261

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The use of topical cyclosporin A in ocular graft-versus-host-disease

12 August 2017

cites work

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12 December 2020

Evolving concepts of diagnosis, pathogenesis, and therapy of Sjögren's syndrome

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12 December 2020

Preclinical safety studies of cyclosporine ophthalmic emulsion.

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12 December 2020

Double-masked trial of cyclosporin versus colchicine and long-term open study of cyclosporin in Behçet's disease

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12 December 2020

Intraocular penetration of topically applied cyclosporine

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12 December 2020

Treatment of severe vernal keratoconjunctivitis with cyclosporine A eyedrops

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12 December 2020

Prolonged survival of allogeneic corneal grafts in rabbits treated with topically applied cyclosporin A: systemic absorption and local immunosuppressive effect

1 reference

12 December 2020

Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily

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12 December 2020

Cyclosporin A on human corneal endothelium

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12 December 2020

Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. CsA Phase 3 Study Group

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12 December 2020

Immunologic and clinical evaluation of postsurgical necrotizing sclerocorneal ulceration

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12 December 2020

Topical use of cyclosporine in the treatment of vernal keratoconjunctivitis.

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12 December 2020

The effect on the cornea of alpha cyclodextrin vehicle for cyclosporin eye drops

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12 December 2020

Combination low dose cyclosporin A and steroid therapy in chronic intraocular inflammation

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12 December 2020

Cyclosporine therapy for uveitis: long-term followup

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12 December 2020

Cyclosporine in the treatment of birdshot retinochoroidopathy

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12 December 2020

Spontaneous canine keratoconjunctivitis sicca. A useful model for human keratoconjunctivitis sicca: treatment with cyclosporine eye drops

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12 December 2020

Topical administration of cyclosporine for treatment of keratoconjunctivitis sicca in dogs

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12 December 2020

Topical cyclosporine in high-risk corneal transplants

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12 December 2020

Corneal concentration and systemic absorption of cyclosporin-A following its topical application in the rabbit eye

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12 December 2020

Pharmacokinetics of cyclosporine in toxicological studies

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12 December 2020

[Comparison between local and systemic administration of cyclosporin A on the effective level in conjunctiva, aqueous humor and serum]

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12 December 2020

A comparison of the clinical utility of the radioimmunoassay, high-performance liquid chromatography, and TDx cyclosporine assays in outpatient renal transplant recipients

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12 December 2020

The role of the lacrimal functional unit in the pathophysiology of dry eye.

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12 December 2020

Mononuclear cell phenotypes and immunoglobulin gene rearrangements in lacrimal gland biopsies from patients with Sjögren's syndrome

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12 December 2020

Long-term therapy with low dose cyclosporin A in ocular Behçet's disease

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12 December 2020

Blood concentrations of cyclosporin a during long-term treatment with cyclosporin a ophthalmic emulsions in patients with moderate to severe dry eye disease

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12 December 2020

Hepatic allograft cyclosporine concentration is independent of the route of cyclosporine administration and correlates with the occurrence of early cellular rejection

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12 December 2020

Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders

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12 December 2020

Low-dose Cyclosporin a in uveitis a long-term follow-up

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12 December 2020

Pharmacokinetic of topical cyclosporin A in the rabbit eye

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12 December 2020

Cyclosporine enemas for treatment-resistant, mildly to moderately active, left-sided ulcerative colitis

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12 December 2020

Efficacy and safety of cyclosporin A ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: a dose-ranging, randomized trial. The Cyclosporin A Phase 2 Study Group

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12 December 2020

Effect of topical cyclosporin A on conjunctival T cells in patients with secondary Sjögren's syndrome

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12 December 2020

Distribution of cyclosporin A in the cornea after topical or oral administration

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12 December 2020

Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A.

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12 December 2020

A specific method for the measurement of cyclosporin A in human whole blood by liquid chromatography-tandem mass spectrometry

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12 December 2020

Randomized, double-masked study of cyclosporine compared to prednisolone in the treatment of endogenous uveitis

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12 December 2020

Precorneal residence times of sodium hyaluronate solutions studied by quantitative gamma scintigraphy

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12 December 2020

Low dose cyclosporin A therapy in chronic posterior uveitis

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12 December 2020

Cyclosporin a: a new era in organ transplantation

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12 December 2020

Intraocular absorption of cyclosporin A eyedrops

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12 December 2020

LC/ESI-MS allows simultaneous and specific quantification of SDZ RAD and cyclosporine, including groups of their metabolites in human blood

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12 December 2020

The carcinogenicity of ciclosporin

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12 December 2020

Penetration of 2% cyclosporin eyedrops into human aqueous humour

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12 December 2020

Local efficacy of cyclosporine in corneal transplant therapy

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12 December 2020

Topical cyclosporin as an adjunct to topical acyclovir treatment in herpetic stromal keratitis

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12 December 2020

Association of cyclosporin to isohexylcyanoacrylate nanospheres and subsequent release in human plasma in vitro

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12 December 2020

The autoimmune nature of aqueous tear deficiency

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12 December 2020

Clinical response does not correlate with intestinal or blood cyclosporine concentrations in patients with Crohn's disease treated with high-dose oral cyclosporine

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12 December 2020

Pilot trial of cyclosporine 1% ophthalmic ointment in the treatment of keratoconjunctivitis sicca

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12 December 2020

Cyclosporin A in the treatment of severe Behçet's uveitis

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12 December 2020

The collagen shield. A new vehicle for delivery of cyclosporin A to the eye

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12 December 2020

Cyclosporine distribution into the conjunctiva, cornea, lacrimal gland, and systemic blood following topical dosing of cyclosporine to rabbit, dog, and human eyes.

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12 December 2020

Penetration of topical cyclosporine into the rabbit cornea, aqueous humor, and serum

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12 December 2020

Cyclosporin A (CyA) in primary Sjögren's syndrome: a double blind study

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12 December 2020

Polyester nanocapsules as new topical ocular delivery systems for cyclosporin A

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12 December 2020

In vivo pharmacological effects of ciclosporin and some analogues

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12 December 2020

Ocular penetration of cyclosporin A. The rabbit eye

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12 December 2020

Collagen as a delivery system for hydrophobic drugs: studies with cyclosporine

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12 December 2020

Topical Cyclosporine A in the management of postkeratoplasty glaucoma and corticosteroid-induced ocular hypertension (CIOH) and the penetration of topical 0.5% cyclosporine A into the cornea and anterior chamber

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12 December 2020

A new perspective on canine keratoconjunctivitis sicca. Treatment with ophthalmic cyclosporine

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12 December 2020

Cyclosporin-A and its metabolites in the anterior chamber after topical and systemic application as determined with high-performance liquid chromatography-electrospray mass spectrometry

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12 December 2020

The treatment of dry eye.

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12 December 2020

Cyclosporin in the treatment of severe chronic idiopathic uveitis

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12 December 2020

Low-dose cyclosporin therapy of ocular inflammation: preliminary report of a long-term follow-up study

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12 December 2020

Performance and specificity of monoclonal immunoassays for cyclosporine monitoring: how specific is specific?

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12 December 2020

Immunosuppressive therapy for chronic uveitis: optimising therapy with steroids and cyclosporin A

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12 December 2020

Distribution of cyclosporin A in ocular tissues after topical administration to albino rabbits and beagle dogs

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12 December 2020

Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines

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12 December 2020

Progress report of an external quality assessment scheme for cyclosporine assay

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12 December 2020

Clinical evaluation of 1% cyclosporine for topical treatment of keratoconjunctivitis sicca in dogs

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12 December 2020

10.2165/00003088-200544030-00003

Identifiers

DOI

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Dimensions Publication ID

12 August 2017

1038213365

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