(Q36070440)

12 August 2017

1 reference

title

Reactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis (English)

1 reference

12 August 2017

main subject

reactive oxygen species

1 reference

Anna Maciag

1

1 reference

12 August 2017

Lucy M Anderson

series ordinal

2

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12 August 2017

publication date

1 January 2005

1 reference

Experimental Lung Research

12 August 2017

published in

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12 August 2017

volume

31

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12 August 2017

issue

1

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12 August 2017

page(s)

83-104

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Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Role of Point Mutation of the K‐ras Gene in Tumorigenesis of B6C3F1 Mouse Lung Lesions Induced by Urethane

21 January 2018

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21 January 2018

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Immortalized bovine pancreatic duct cells become tumorigenic after transfection with mutant k-ras

21 January 2018

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Wildtype Kras2 can inhibit lung carcinogenesis in mice

21 January 2018

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Differential distribution and increased levels of ras proteins during lung development

21 January 2018

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Selective mutation of K-ras by N-ethylnitrosourea shifts from codon 12 to codon 61 during fetal mouse lung maturation

21 January 2018

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Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxin

21 January 2018

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LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer

21 January 2018

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Decreased susceptibility to NMU-induced mammary carcinogenesis in transgenic rats carrying multiple copies of a rat ras gene driven by the rat Harvey ras promoter

21 January 2018

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

21 January 2018

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

21 January 2018

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Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene

21 January 2018

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Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

21 January 2018

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Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 January 2018

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Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

21 January 2018

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Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

21 January 2018

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Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species

21 January 2018

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Oncogenic H-Ras enhances DNA repair through the Ras/phosphatidylinositol 3-kinase/Rac1 pathway in NIH3T3 cells. Evidence for association with reactive oxygen species.

21 January 2018

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Differential activation of the Rac pathway by Ha-Ras and K-Ras

21 January 2018

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Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha

21 January 2018

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Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals.

21 January 2018

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V-Ha-Ras overexpression induces superoxide production and alters levels of primary antioxidant enzymes

21 January 2018

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Mutant K-rasV12 increases COX-2, peroxides and DNA damage in lung cells

21 January 2018

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A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells.

21 January 2018

1 reference

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Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway

21 January 2018

1 reference

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Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA.

21 January 2018

1 reference

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Induction of cytosolic phospholipase A2 by oncogenic Ras in human non-small cell lung cancer

21 January 2018

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DNA oxidation induced by cyclooxygenase-2.

21 January 2018

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Protection by quercetin against cooking oil fumes-induced DNA damage in human lung adenocarcinoma CL-3 cells: role of COX-2.

21 January 2018

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Role of transcription factor Egr-1 in phorbol ester-induced phenylethanolamine N-methyltransferase gene expression

21 January 2018

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The role of cyclooxygenases in inflammation, cancer, and development

21 January 2018

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Many actions of cyclooxygenase-2 in cellular dynamics and in cancer

21 January 2018

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Cyclooxygenase-2 (COX-2) mRNA expression levels in normal lung tissues and non-small cell lung cancers.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01902140490495048

Increased cyclooxygenase 2 (COX-2) expression occurs frequently in precursor lesions of human adenocarcinoma of the lung.

21 January 2018

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https://api.crossref.org/works/10.1080%2F01902140490495048

Cyclooxygenase-2 in human non-small cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1080%2F01902140490495048

Prognostic significance of cyclooxygenase 2 mRNA expression in non-small cell lung cancer.

21 January 2018

1 reference

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Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer

21 January 2018

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The role of oxidative stress in indium phosphide-induced lung carcinogenesis in rats.

21 January 2018

1 reference

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Cyclooxygenase-2 expression is abundant in alveolar type II cells in lung cancer-sensitive mouse strains and in premalignant lesions.

21 January 2018

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The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice

21 January 2018

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Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice

21 January 2018

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Oxidative DNA damage, antioxidants, and cancer

21 January 2018

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21 January 2018

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On the origin of p53 G:C --> T:A transversions in lung cancers

21 January 2018

1 reference

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Lung cancer patients have increased 8-hydroxydeoxyguanosine levels in peripheral lung tissue DNA.

21 January 2018

1 reference

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Activity of glutathione-metabolizing and antioxidant enzymes in malignant and benign tumors of human lungs

21 January 2018

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NAD(P)H: quinone oxidoreductase polymorphism and lung cancer in Taiwan

21 January 2018

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Analysis of NQO1, GSTP1, and MnSOD genetic polymorphisms on lung cancer risk in Taiwan

21 January 2018

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Manganese superoxide dismutase alanine-to-valine polymorphism at codon 16 and lung cancer risk.

21 January 2018

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A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung

21 January 2018

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Inherited variants in MYH are unlikely to contribute to the risk of lung carcinoma.

21 January 2018

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Fruits and vegetables and lung cancer: Findings from the European Prospective Investigation into Cancer and Nutrition

21 January 2018

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https://api.crossref.org/works/10.1080%2F01902140490495048

Aspirin and lung cancer in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Regular aspirin use and lung cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Risk of lung carcinoma among users of nonsteroidal antiinflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Aspirin use and lung cancer in men

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Long-term toxicity studies of ozone in F344/N rats and B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Two-year and lifetime toxicity and carcinogenicity studies of ozone in B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Changes in levels of 8-hydroxyguanine in DNA, its repair and OGG1 mRNA in rat lungs after intratracheal administration of diesel exhaust particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Chemoprevention of lung cancer by isothiocyanates and their conjugates in A/J mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

A review of animal model studies of tomato carotenoids, lycopene, and cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

A simple technique for quantitation of low levels of DNA damage in individual cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F01902140490495048

10.1080/01902140490495048

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference