(Q36080545)

English

Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Streptococcus pneumoniae

1 reference

based on heuristic

inferred from title

author name string

Jiyun Lee

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Kensei Komatsu

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Byung Cheol Lee

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jae Hyang Lim

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Hirofumi Jono

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Haidong Xu

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Hirofumi Kai

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Z John Zhang

8

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Chen Yan

9

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jian-Dong Li

10

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

0 references

publication date

18 May 2012

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

12 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

27

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

22799-22811

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Differential regulation of Streptococcus pneumoniae-induced human MUC5AC mucin expression through distinct MAPK pathways

1 reference

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Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy

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Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease

1 reference

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Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury

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Gene expression differences in infected and noninfected middle ear complementary DNA libraries

1 reference

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Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice

1 reference

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Ciprofloxacin 0.3%/dexamethasone 0.1% sterile otic suspension for the topical treatment of ear infections: a review of the literature

1 reference

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2 October 2017

Glucocorticoids inhibit nontypeable Haemophilus influenzae-induced MUC5AC mucin expression via MAPK phosphatase-1-dependent inhibition of p38 MAPK.

1 reference

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Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease

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Streptococcus pneumoniae synergizes with nontypeable Haemophilus influenzae to induce inflammation via upregulating TLR2

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CYLD is a crucial negative regulator of innate immune response in Escherichia coli pneumonia

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Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling

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Changes in serotypes and antimicrobial susceptibility of invasive Streptococcus pneumoniae strains in Cleveland: a quarter century of experience

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Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alpha signaling pathways in human airway epithelial cells

1 reference

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2 October 2017

Synergistic induction of MUC5AC mucin by nontypeable Haemophilus influenzae and Streptococcus pneumoniae

1 reference

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Pooled analysis of two clinical trials comparing the clinical outcomes of topical ciprofloxacin/dexamethasone otic suspension and polymyxin B/neomycin/hydrocortisone otic suspension for the treatment of acute otitis externa in adults and children

1 reference

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Multidrug-resistant Streptococcus pneumoniae infections: current and future therapeutic options.

1 reference

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2 October 2017

Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice

1 reference

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2 October 2017

Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3

1 reference

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2 October 2017

Opposing roles of PAK2 and PAK4 in synergistic induction of MUC5AC mucin by bacterium NTHi and EGF.

1 reference

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2 October 2017

Novel strategies for inhibition of the p38 MAPK pathway.

1 reference

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2 October 2017

Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation

1 reference

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2 October 2017

MAPK phosphatases--regulating the immune response

1 reference

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2 October 2017

TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation

1 reference

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2 October 2017

Regulation of MAP kinases by MAP kinase phosphatases.

1 reference

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2 October 2017

Capturing cyclic nucleotides in action: snapshots from crystallographic studies

1 reference

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Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases.

1 reference

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Brief review of the clinical effectiveness of PREVENAR against otitis media

1 reference

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2 October 2017

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

1 reference

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2 October 2017

Role of nuclear Ca2+/calmodulin-stimulated phosphodiesterase 1A in vascular smooth muscle cell growth and survival

1 reference

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2 October 2017

Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses

1 reference

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2 October 2017

Phosphodiesterase inhibitors in airways disease

1 reference

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2 October 2017

Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells

1 reference

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2 October 2017

Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

1 reference

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2 October 2017

Negative regulation of toll-like receptor-mediated immune responses

1 reference

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2 October 2017

Intratympanic steroid perfusion for refractory sudden sensorineural hearing loss

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2 October 2017

Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development

1 reference

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2 October 2017

Phosphodiesterase-4 inhibitors in the treatment of inflammatory lung disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391144

2 October 2017

Review of randomized controlled trials on pneumococcal vaccination for prevention of otitis media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391144

2 October 2017

Transforming Growth Factor-β-Smad Signaling Pathway Negatively Regulates Nontypeable Haemophilus influenzae-induced MUC5AC Mucin Transcription via Mitogen-activated Protein Kinase (MAPK) Phosphatase-1-dependent Inhibition of p38 MAPK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391144

2 October 2017

Exploitation of host epithelial signaling networks by respiratory bacterial pathogens

1 reference

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2 October 2017

Mucin gene expression in the effusions of otitis media with effusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391144

2 October 2017

Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391144

2 October 2017

Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription

1 reference

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2 October 2017

Immortalization of normal adult human middle ear epithelial cells using a retrovirus containing the E6/E7 genes of human papillomavirus type 16.

1 reference

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2 October 2017

Mucus clearance as a primary innate defense mechanism for mammalian airways

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Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia

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2 October 2017

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1 reference

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2 October 2017

The burden of otitis media

1 reference

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TNF-alpha in the regulation of MUC5AC secretion: some aspects of cytokine-induced mucin hypersecretion on the in vitro model

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Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group

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2 October 2017

Control of mucin transcription by diverse injury-induced signaling pathways

1 reference

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p38 MAPK signalling cascades in inflammatory disease

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Nontypeable Haemophilus influenzae: pathogenesis and prevention

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Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells

1 reference

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Epithelial mucin genes

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2 October 2017

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Otitis media in children: to treat or not to treat?

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Learning Disabilities and Conductive Hearing Loss Involving Otitis Media

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Immunoprophylaxis of Otitis Media

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11 July 2018

Cost-effectiveness considerations in otitis media treatment

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21 January 2018

Effect of conjugate pneumococcal vaccine followed by polysaccharide pneumococcal vaccine on recurrent acute otitis media: a randomised study

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21 January 2018

Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States

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21 January 2018

Detection of mucin gene expression in normal rat middle ear mucosa by reverse transcriptase-polymerase chain reaction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337378

21 January 2018

Nitric oxide mediates mucin secretion in endotoxin-induced otitis media with effusion.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337378

21 January 2018

Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337378

21 January 2018

Participation of Ras and extracellular regulated kinase in the hyperplastic response of middle-ear mucosa during bacterial otitis media

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.337378

21 January 2018

Growth factors and their receptors in the middle ear mucosa during otitis media

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https://api.crossref.org/works/10.1074%2FJBC.M111.337378

21 January 2018

Cyclic nucleotide research -- still expanding after half a century

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21 January 2018

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Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

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21 January 2018

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-kappaB.

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21 January 2018

Phosphodiesterase-4 inhibition in COPD.

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21 January 2018

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

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21 January 2018

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21 January 2018

Treatment of sensorineural hearing loss in acute viral otitis media with intratympanic dexamethasone and hyaluronic acid in comparison with intravenous therapy

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21 January 2018

Otitis Media with Effusion: Components Which Contribute to the Viscous Properties

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21 January 2018

Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

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Fluorescent sensors for rapid monitoring of intracellular cGMP

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https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

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inferred from PubMed ID database lookup

Emergence of nonvaccine serotypes following introduction of pneumococcal conjugate vaccine: cause and effect?

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https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

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inferred from PubMed ID database lookup

A novel role for IkappaB kinase (IKK) alpha and IKKbeta in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

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Treatment of erectile dysfunction after radical prostatectomy with sildenafil citrate (Viagra)

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Mucin gene expression in human middle ear epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Audiometry and tympanometry in relation to middle ear effusions in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled multicenter study on chronic suppurative otitis media treated with topical applications of ciprofloxacin 0.2% solution in single-dose containers or combination of polymyxin B, neomycin, and hydrocortisone suspension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22610099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.337378

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

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