Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36080665)
Watch
English
Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4577825
retrieved
12 August 2017
title
Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4577825
retrieved
12 August 2017
author
Ho-Jin Lee
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
Jie Zheng
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
author name string
De-Li Shi
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
language of work or name
English
0 references
publication date
22 August 2015
1 reference
stated in
Europe PubMed Central
PMCID
4577825
retrieved
12 August 2017
published in
eLife
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
volume
4
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
page(s)
e08142
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
cites work
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Synthesis of potent dishevelled PDZ domain inhibitors guided by virtual screening and NMR studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
PDZ domains and their binding partners: structure, specificity, and modification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dishevelled: The hub of Wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Proximal events in Wnt signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Identification of tripeptides recognized by the PDZ domain of Dishevelled
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
A specificity map for the PDZ domain family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Optimizing Dvl PDZ domain inhibitor by exploring chemical space.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Mechanism of activation of the Formin protein Daam1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Planar cell polarity signaling in vertebrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Identification of a specific inhibitor of the dishevelled PDZ domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The nonsteroidal anti-inflammatory drug Exisulind selectively induces apoptosis via JNK in secondary acute myeloid leukemia after myelodysplastic syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dishevelled and Wnt signaling: is the nucleus the final frontier?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The Wnt signaling pathway in development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
A mechanism for Wnt coreceptor activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
HADDOCK: a protein-protein docking approach based on biochemical or biophysical information
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dishevelled: at the crossroads of divergent intracellular signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
dishevelled and armadillo act in the wingless signalling pathway in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
2 October 2017
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
11 July 2018
JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
11 July 2018
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
11 July 2018
Analysis of Dishevelled signalling pathways during Xenopus development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
11 July 2018
dishevelled is required during wingless signaling to establish both cell polarity and cell identity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
11 July 2018
Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
23 September 2018
Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
23 September 2018
Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577825
retrieved
23 September 2018
Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26297804
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Antagonistic interaction between IGF and Wnt/JNK signaling in convergent extension in Xenopus embryo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26297804
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of a hidden folding intermediate in the focal adhesion target domain: Implications for its function and folding
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26297804
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A role for Wnts in morpho-genesis and tissue polarity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26297804
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.7554/ELIFE.08142
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PMCID
4577825
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
PubMed ID
26297804
1 reference
stated in
Europe PubMed Central
PMCID
4577825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26297804%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 June 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit