(Q36080691)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26371187%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity (English)

1 reference

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24 February 2020

1

1 reference

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24 February 2020

Ryan H Moy

2

1 reference

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24 February 2020

Michael J May

12

1 reference

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24 February 2020

author name string

Mario Noti

3

1 reference

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24 February 2020

Lisa C Osborne

4

1 reference

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24 February 2020

Mark C Siracusa

5

1 reference

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24 February 2020

Theresa Alenghat

6

1 reference

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24 February 2020

Bigang Liu

7

1 reference

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24 February 2020

Kelly A McCorkell

8

1 reference

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24 February 2020

Amy E Troy

9

1 reference

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24 February 2020

Gregory D Rak

10

1 reference

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24 February 2020

Yinling Hu

11

1 reference

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24 February 2020

Hak-Ling Ma

13

1 reference

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24 February 2020

Lynette A Fouser

14

1 reference

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24 February 2020

Gregory F Sonnenberg

15

1 reference

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24 February 2020

David Artis

16

1 reference

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24 February 2020

language of work or name

English

0 references

publication date

14 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26371187%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

24 February 2020

published in

1 reference

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24 February 2020

volume

212

1 reference

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24 February 2020

issue

10

1 reference

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24 February 2020

page(s)

1513-1528

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26371187%20AND%20SRC:MED&resulttype=core&format=json

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

24 February 2020

cites work

1 reference

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The biology of innate lymphoid cells

2 October 2017

1 reference

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Activated type 2 innate lymphoid cells regulate beige fat biogenesis

2 October 2017

1 reference

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Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

2 October 2017

1 reference

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Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18

2 October 2017

1 reference

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Innate lymphoid cells in inflammation and immunity

2 October 2017

1 reference

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Innate lymphoid cells regulate intestinal epithelial cell glycosylation

2 October 2017

1 reference

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Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells.

2 October 2017

1 reference

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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

2 October 2017

1 reference

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MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion

2 October 2017

1 reference

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The intestinal epithelium is an integral component of a communications network

2 October 2017

1 reference

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Anatomical localization of commensal bacteria in immune cell homeostasis and disease

2 October 2017

1 reference

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Regulation of intestinal health and disease by innate lymphoid cells

2 October 2017

1 reference

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Development and regulation of RORγt(+) innate lymphoid cells

2 October 2017

1 reference

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Intestinal epithelial cells: regulators of barrier function and immune homeostasis

2 October 2017

1 reference

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Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis

2 October 2017

1 reference

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Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.

2 October 2017

1 reference

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IKKβ in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites

2 October 2017

1 reference

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IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis.

2 October 2017

1 reference

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Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

2 October 2017

1 reference

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Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells

2 October 2017

1 reference

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Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection.

2 October 2017

1 reference

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Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

2 October 2017

1 reference

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The biology of thymic stromal lymphopoietin (TSLP).

2 October 2017

1 reference

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Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

2 October 2017

1 reference

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Intestinal epithelial cells as mediators of the commensal-host immune crosstalk

2 October 2017

1 reference

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Innate lymphoid cells--how did we miss them?

2 October 2017

1 reference

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The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells

2 October 2017

1 reference

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Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium

2 October 2017

1 reference

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Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Thymic stromal lymphopoietin (TSLP)-induced polyclonal B-cell activation and autoimmunity are mediated by CD4+ T cells and IL-4.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Innate lymphoid cells: emerging insights in development, lineage relationships, and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells

2 October 2017

1 reference

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Intestinal homeostasis and its breakdown in inflammatory bowel disease

2 October 2017

1 reference

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IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease

2 October 2017

1 reference

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The intestinal epithelial barrier in the control of homeostasis and immunity.

2 October 2017

1 reference

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Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22.

2 October 2017

1 reference

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CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

2 October 2017

1 reference

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The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

2 October 2017

1 reference

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Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes

2 October 2017

1 reference

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Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38.

2 October 2017

1 reference

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Lymphotoxin beta receptor signaling in intestinal epithelial cells orchestrates innate immune responses against mucosal bacterial infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Immune adaptations that maintain homeostasis with the intestinal microbiota

2 October 2017

1 reference

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Epithelial barriers in homeostasis and disease

2 October 2017

1 reference

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The NF-kappaB-independent functions of IKK subunits in immunity and cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.

2 October 2017

1 reference

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Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen

2 October 2017

1 reference

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IKK/NF-kappaB signaling in intestinal epithelial cells controls immune homeostasis in the gut.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Opposing functions of IKKbeta during acute and chronic intestinal inflammation

2 October 2017

1 reference

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The regulation of IgA class switching.

2 October 2017

1 reference

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NF-kappaB in inflammatory bowel disease

2 October 2017

1 reference

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Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut.

2 October 2017

1 reference

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IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

2 October 2017

1 reference

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Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

2 October 2017

1 reference

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Hydrodynamic gene delivery: its principles and applications

2 October 2017

1 reference

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NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB

2 October 2017

1 reference

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Citrobacter rodentium-induced NF-kappaB activation in hyperproliferating colonic epithelia: role of p65 (Ser536) phosphorylation

2 October 2017

1 reference

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Signalling pathways and molecular interactions of NOD1 and NOD2

2 October 2017

1 reference

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Citrobacter rodentium of mice and man.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Lymphotoxin and LIGHT signaling pathways and target genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

A20 controls intestinal homeostasis through cell-specific activities

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

IKKalpha is required to maintain skin homeostasis and prevent skin cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4577836

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

23 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141831

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141831

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141831

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141831

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141831

Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules

21 January 2018

1 reference

12 December 2020

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

1 reference

12 December 2020

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

1 reference

12 December 2020

Interactions between epithelial cells and immune cells in the intestine

1 reference

12 December 2020

Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells

1 reference

12 December 2020

Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally different

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20141831

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26371187%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26371187%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

26371187

1 reference