Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36086426)
Watch
English
pfmdr1 amplification is related to increased Plasmodium falciparum in vitro sensitivity to the bisquinoline piperaquine
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
title
pfmdr1 amplification is related to increased Plasmodium falciparum in vitro sensitivity to the bisquinoline piperaquine
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
main subject
MDR1
0 references
Plasmodium falciparum
0 references
author
François Nosten
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Maria Isabel Veiga
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Pedro E. Ferreira
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Maja Malmberg
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
José Pedro Gil
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author name string
L Jörnhagen
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
A Björkman
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
language of work or name
English
0 references
publication date
16 April 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Antimicrobial Agents and Chemotherapy
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
56
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
3615-3619
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
cites work
Antimalarial efficacy of piperaquine-based antimalarial combination therapies: facts and uncertainties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Transporters as mediators of drug resistance in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Artemisinin resistance: current status and scenarios for containment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Simple histidine-rich protein 2 double-site sandwich enzyme-linked immunosorbent assay for use in malaria drug sensitivity testing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Piperaquine: a resurgent antimalarial drug.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
In vitro activities of piperaquine and other 4-aminoquinolines against clinical isolates of Plasmodium falciparum in Cameroon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Human malaria parasites in continuous culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
2 October 2017
Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
11 July 2018
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
11 July 2018
Pharmacokinetics and ex vivo pharmacodynamic antimalarial activity of dihydroartemisinin-piperaquine in patients with uncomplicated falciparum malaria in Vietnam
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
11 July 2018
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
11 July 2018
Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
11 July 2018
Dihydroartemisinin-piperaquine versus artemether-lumefantrine, in the treatment of uncomplicated Plasmodium falciparum malaria in central Sudan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
Genome wide gene amplifications and deletions in Plasmodium falciparum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
Coartem (artemether-lumefantrine) in Africa: the beginning of the end?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3393437
retrieved
23 September 2018
Identifiers
DOI
10.1128/AAC.06350-11
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PMC publication ID
3393437
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed publication ID
22508315
1 reference
stated in
Europe PubMed Central
PMC publication ID
3393437
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22508315%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit