(Q36090648)

12 August 2017

2 references

19 July 2022

Selectin antagonists : therapeutic potential in asthma and COPD. (English)

1 reference

chronic obstructive pulmonary disease

12 August 2017

2 references

19 July 2022

1 reference

Suzanne J Romano

1

1 reference

12 August 2017

1 January 2005

1 reference

Treatments in Respiratory Medicine

12 August 2017

2 references

12 August 2017

19 July 2022

4

1 reference

12 August 2017

85-94

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12 August 2017

2

1 reference

https://scigraph.springernature.com/pub.10.2165/00151829-200504020-00002

12 August 2017

0 references

cites work

Oligonucleotide inhibitors of P-selectin-dependent neutrophil-platelet adhesion

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00151829-200504020-00002

Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00151829-200504020-00002

Selective intracellular delivery of dexamethasone into activated endothelial cells using an E-selectin-directed immunoconjugate.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00151829-200504020-00002

The selectins and their ligands

21 January 2018

1 reference

12 December 2020

Endothelial leukocyte adhesion molecule-1 mediates antigen-induced acute airway inflammation and late-phase airway obstruction in monkeys

1 reference

12 December 2020

Targeting selectins for the treatment of respiratory diseases.

1 reference

12 December 2020

Asthma: new drug targets and innovative therapeutics - SMi Conference. 28-29 March 2001, London, UK

1 reference

12 December 2020

Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins

1 reference

12 December 2020

L-Selectin is required for the development of airway hyperresponsiveness but not airway inflammation in a murine model of asthma

1 reference

12 December 2020

Adhesion molecules and inflammatory injury.

1 reference

12 December 2020

Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice

1 reference

12 December 2020

Searching for medicine's sweet spot

1 reference

12 December 2020

Blockade of CD49d (alpha4 integrin) on intrapulmonary but not circulating leukocytes inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma

1 reference

12 December 2020

1 reference

12 December 2020

Perspectives for TNF-alpha-targeting therapies

1 reference

12 December 2020

Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs

1 reference

12 December 2020

L-selectin shedding regulates leukocyte recruitment

1 reference

12 December 2020

Deaths: final data for 1999.

1 reference

12 December 2020

Cracking the carbohydrate code for selectin recognition

1 reference

12 December 2020

New treatments for COPD.

1 reference

12 December 2020

Inhibition of L-selectin-mediated leukocyte rolling by synthetic glycoprotein mimics.

1 reference

12 December 2020

Leukocyte trafficking mediated by selectin-carbohydrate interactions

1 reference

12 December 2020

Leukocyte adhesion deficiency II-from A to almost Z.

1 reference

12 December 2020

CD24, a mucin-type glycoprotein, is a ligand for P-selectin on human tumor cells

1 reference

12 December 2020

Are eosinophils out of asthma?

1 reference

12 December 2020

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

1 reference

12 December 2020

The role of adhesion molecules in allergic inflammation and their suitability as targets of antiallergic therapy.

1 reference

12 December 2020

Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs.

1 reference

12 December 2020

Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep

1 reference

12 December 2020

Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis

1 reference

12 December 2020

Protective effects of oligosaccharides in P-selectin-dependent lung injury

1 reference

12 December 2020

Anti-L-selectin antibody treatment of hemorrhagic-traumatic shock in baboons

1 reference

12 December 2020

Important roles for L-selectin and ICAM-1 in the development of allergic airway inflammation in asthma.

1 reference

12 December 2020

Mouse bone marrow-derived mast cells roll on P-selectin under conditions of flow in vivo.

1 reference

12 December 2020

Differential leukocyte recruitment from whole blood via endothelial adhesion molecules under shear conditions

1 reference

12 December 2020

Mechanisms in COPD: differences from asthma

1 reference

12 December 2020

BMS-190394, a selectin inhibitor, prevents rat cutaneous inflammatory reactions

1 reference

12 December 2020

In vivo neutrophil and lymphocyte function studies in a patient with leukocyte adhesion deficiency type II.

1 reference

12 December 2020

Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity

1 reference

12 December 2020

Severe asthma and COPD--the good, the bad and the ugly

1 reference

12 December 2020

Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins.

1 reference

12 December 2020

Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)

1 reference

12 December 2020

Reduction of allergic airway responses in P-selectin-deficient mice

1 reference

12 December 2020

Selectin-carbohydrate interactions in shear flow

1 reference

12 December 2020

The selectins: vascular adhesion molecules

1 reference

12 December 2020

Functional Role for Selectins in the Pathogenesis of Cerebral Ischemia.

1 reference

12 December 2020

Cylexin: a P-selectin inhibitor prolongs heart allograft survival in hypersensitized rat recipients

1 reference

12 December 2020

Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269).

1 reference

12 December 2020

Mechanisms that regulate the function of the selectins and their ligands

1 reference

12 December 2020

Developments in the treatment of chronic obstructive pulmonary disease: the clinical picture

1 reference

12 December 2020

Non-eosinophilic asthma: importance and possible mechanisms

1 reference

12 December 2020

The effect of anti-L-selectin (aselizumab) in multiple traumatized patients--results of a phase II clinical trial

1 reference

12 December 2020

Protective role of synthetic sialylated oligosaccharide in sepsis-induced acute lung injury

1 reference

12 December 2020

Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides.

1 reference

12 December 2020

Inhibition of adhesion of human neutrophils and eosinophils to P-selectin by the sialyl Lewis antagonist TBC1269: preferential activity against neutrophil adhesion in vitro

1 reference

12 December 2020

Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides

1 reference

12 December 2020

Sialyl Lewis(x) (sLe(x)) and an sLe(x) mimetic, CGP69669A, disrupt E-selectin-dependent leukocyte rolling in vivo.

1 reference

12 December 2020

Recombinant soluble form of PSGL-1 accelerates thrombolysis and prevents reocclusion in a porcine model

1 reference

12 December 2020

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

1 reference

12 December 2020

Therapeutic inhibition of carbohydrate-protein interactions in vivo

1 reference

12 December 2020

1 reference

12 December 2020

Selectin synthesis and inflammation

1 reference

12 December 2020

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

1 reference

12 December 2020

Development of synthetic pan-selectin antagonists: a new treatment strategy for chronic inflammation in asthma

1 reference

12 December 2020

Of man and mouse: leukocyte and endothelial adhesion molecule deficiencies.

1 reference

12 December 2020

In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes

1 reference

12 December 2020

Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1

1 reference

12 December 2020

Insights into selectin function from knockout mice

1 reference

12 December 2020

Asthma therapy for the 21st century.

1 reference

12 December 2020

Protective effects of selectin chimeras in neutrophil-mediated lung injury.

1 reference

12 December 2020

Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression

1 reference

12 December 2020

57th AAAAI. Novel drugs

1 reference

12 December 2020

Development of cell adhesion molecule antagonists as therapeutics for asthma and COPD.

1 reference

12 December 2020

10.2165/00151829-200504020-00002

Identifiers

DOI

1 reference

PubMed ID

15813660

Dimensions Publication ID

12 August 2017

0 references

0 references

1 reference

PubMed ID

15813660