(Q36108709)

12 August 2017

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title

The hardship of obesity: a soft-wired hypothalamus (English)

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12 August 2017

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Tamas L Horvath

1

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PubMed ID

15856063

12 August 2017

language of work or name

English

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publication date

1 May 2005

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12 August 2017

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12 August 2017

8

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12 August 2017

5

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12 August 2017

561-565

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https://scigraph.springernature.com/pub.10.1038/nn1453

12 August 2017

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cites work

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21 January 2018

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Weight-reducing effects of the plasma protein encoded by the obese gene

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Effects of the obese gene product on body weight regulation in ob/ob mice

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Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

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Identification and expression cloning of a leptin receptor, OB-R

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Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

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Identification of targets of leptin action in rat hypothalamus

21 January 2018

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

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Electron microscopic immunohistochemical localization of ?-MSH in the rat brain

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Melanocortin receptors in leptin effects.

21 January 2018

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Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

21 January 2018

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21 January 2018

1 reference

Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

21 January 2018

1 reference

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

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1 reference

Neuropeptide-Y innervation of beta-endorphin-containing cells in the rat mediobasal hypothalamus: a light and electron microscopic double immunostaining analysis

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Rapid rewiring of arcuate nucleus feeding circuits by leptin.

21 January 2018

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Hypothalamic melanocortin neurons integrate signals of energy state

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The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice

21 January 2018

1 reference

Distribution of the pro-opiomelanocortin derived peptides, adrenocorticotrope hormone, alpha-melanocyte-stimulating hormone and beta-endorphin (ACTH, alpha-MSH, beta-END) in the rat hypothalamus.

21 January 2018

1 reference

Leptin activates hypothalamic CART neurons projecting to the spinal cord.

21 January 2018

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A role for melanin-concentrating hormone in the central regulation of feeding behaviour

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Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats.

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Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia.

21 January 2018

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21 January 2018

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Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation

21 January 2018

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Trophic action of leptin on hypothalamic neurons that regulate feeding

21 January 2018

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Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

21 January 2018

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Hypothalamic orexin neurons regulate arousal according to energy balance in mice

21 January 2018

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Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

21 January 2018

1 reference

Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index

21 January 2018

1 reference

Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite

21 January 2018

1 reference

A good night's sleep: future antidote to the obesity epidemic?

21 January 2018

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In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus

21 January 2018

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Evidence for structural plasticity in the supraoptic nucleus of the rat hypothalamus in relation to gestation and lactation

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NN1453

1 reference

12 August 2017

1 reference

PubMed ID

15856063