(Q36116459)

12 August 2017

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title

Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions (English)

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12 August 2017

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Teddy Kosoglou

1

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12 August 2017

Paul Statkevich

2

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12 August 2017

Amy O Johnson-Levonas

3

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12 August 2017

John F Paolini

4

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12 August 2017

Arthur J Bergman

5

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12 August 2017

Kevin B Alton

6

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12 August 2017

language of work or name

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1 January 2005

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Clinical Pharmacokinetics

12 August 2017

published in

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12 August 2017

volume

44

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12 August 2017

issue

5

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12 August 2017

page(s)

467-494

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https://scigraph.springernature.com/pub.10.2165/00003088-200544050-00002

12 August 2017

exact match

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cites work

Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects

1 reference

12 December 2020

Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia

1 reference

12 December 2020

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

1 reference

12 December 2020

Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

1 reference

12 December 2020

1 reference

12 December 2020

Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia

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12 December 2020

Clinical pharmacokinetics of fibric acid derivatives (fibrates).

1 reference

12 December 2020

Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia

1 reference

12 December 2020

Differentiating members of the thiazolidinedione class: a focus on safety

1 reference

12 December 2020

In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461

1 reference

12 December 2020

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

1 reference

12 December 2020

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

1 reference

12 December 2020

[The prognostic value of liver function tests--clinical aspects, laboratory chemical parameters and quantitative function tests]

1 reference

12 December 2020

Ezetimibe: the first in a novel class of selective cholesterol-absorption inhibitors

1 reference

12 December 2020

Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin

1 reference

12 December 2020

Treatment patterns and distribution of low-density lipoprotein cholesterol levels in treatment-eligible United States adults

1 reference

12 December 2020

Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil.

1 reference

12 December 2020

The Yin and Yang of cholesteryl ester transfer protein and atherosclerosis

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12 December 2020

Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers

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12 December 2020

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

1 reference

12 December 2020

Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

1 reference

12 December 2020

Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption

1 reference

12 December 2020

Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia

1 reference

12 December 2020

Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors

1 reference

12 December 2020

Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

1 reference

12 December 2020

Review article: drug interactions with agents used to treat acid-related diseases

1 reference

12 December 2020

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

1 reference

12 December 2020

Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

1 reference

12 December 2020

Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia

1 reference

12 December 2020

A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe

1 reference

12 December 2020

Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

1 reference

12 December 2020

Pharmacodynamic interaction between ezetimibe and rosuvastatin

1 reference

12 December 2020

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

1 reference

12 December 2020

Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies

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12 December 2020

Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe

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12 December 2020

Effects of ezetimibe on the pharmacodynamics and pharmacokinetics of lovastatin

1 reference

12 December 2020

Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial

1 reference

12 December 2020

Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial).

1 reference

12 December 2020

Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia

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12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

1 reference

12 December 2020

New drugs for the treatment of hypercholesterolaemia

1 reference

12 December 2020

MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial

1 reference

12 December 2020

Bile acid sequestrants

1 reference

12 December 2020

Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial

1 reference

12 December 2020

Effectiveness of statin titration on low-density lipoprotein cholesterol goal attainment in patients at high risk of atherogenic events

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12 December 2020

10.2165/00003088-200544050-00002

Identifiers

DOI

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Dimensions Publication ID

12 August 2017

1031340540

0 references

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