(Q36127172)

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Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic steps

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Kinetic partitioning between synthetic and editing pathways in class I aminoacyl-tRNA synthetases occurs at both pre-transfer and post-transfer hydrolytic steps (English)

1 reference

Europe PubMed Central

12 August 2017

author name string

Nevena Cvetesic

1

1 reference

Europe PubMed Central

12 August 2017

John J Perona

2

1 reference

Europe PubMed Central

12 August 2017

Ita Gruic-Sovulj

3

1 reference

Europe PubMed Central

12 August 2017

language of work or name

0 references

publication date

30 May 2012

1 reference

Europe PubMed Central

12 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

12 August 2017

287

1 reference

Europe PubMed Central

12 August 2017

30

1 reference

Europe PubMed Central

12 August 2017

25381-25394

1 reference

Europe PubMed Central

12 August 2017

Quality control in aminoacyl-tRNA synthesis its role in translational fidelity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Substrate specificity of bacterial prolyl-tRNA synthetase editing domain is controlled by a tunable hydrophobic pocket

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Quality control in tRNA charging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

A recurrent loss-of-function alanyl-tRNA synthetase (AARS) mutation in patients with Charcot-Marie-Tooth disease type 2N (CMT2N)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Fidelity escape by the unnatural amino acid β-hydroxynorvaline: an efficient substrate for Escherichia coli threonyl-tRNA synthetase with toxic effects on growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Aminoacyl transfer rate dictates choice of editing pathway in threonyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Partitioning of tRNA-dependent editing between pre- and post-transfer pathways in class I aminoacyl-tRNA synthetases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

The kinetic and chemical mechanism of high-fidelity DNA polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

tRNA-dependent pre-transfer editing by prokaryotic leucyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Resampling and editing of mischarged tRNA prior to translation elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

CP1-dependent partitioning of pretransfer and posttransfer editing in leucyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

RNA-assisted catalysis in a protein enzyme: The 2'-hydroxyl of tRNA(Thr) A76 promotes aminoacylation by threonyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Norvaline is accumulated after a down-shift of oxygen in Escherichia coli W3110

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

DNA polymerases and aminoacyl-tRNA synthetases: shared mechanisms for ensuring the fidelity of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Role of induced fit in enzyme specificity: a molecular forward/reverse switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

[3'-32P]-labeling tRNA with nucleotidyltransferase for assaying aminoacylation and peptide bond formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Pre-transfer editing by class II prolyl-tRNA synthetase: role of aminoacylation active site in "selective release" of noncognate amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Long-range intramolecular signaling in a tRNA synthetase complex revealed by pre-steady-state kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Aminoacyl-tRNA synthetases: versatile players in the changing theater of translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Attenuation of the editing activity of the Escherichia coli leucyl-tRNA synthetase allows incorporation of novel amino acids into proteins in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Modulation of tRNAAla identity by inorganic pyrophosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Aminoacyl-tRNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Transfer RNA identity contributes to transition state stabilization during aminoacyl-tRNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Enzyme structure with two catalytic sites for double-sieve selection of substrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Incorporation of norvaline at leucine positions in recombinant human hemoglobin expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Conformational coupling in DNA polymerase fidelity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Alternative pathways for editing non-cognate amino acids by aminoacyl-tRNA synthetases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Establishing the misacylation/deacylation of the tRNA pathway for the editing mechanism of prokaryotic and eukaryotic valyl-tRNA synthetases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Editing mechanisms in protein synthesis. Rejection of valine by the isoleucyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 October 2017

Substrate specificity and catalysis by the editing active site of Alanyl-tRNA synthetase from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 July 2018

Kinetic discrimination of tRNA identity by the conserved motif 2 loop of a class II aminoacyl-tRNA synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 July 2018

Divergence in noncognate amino acid recognition between class I and class II lysyl-tRNA synthetases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 July 2018

Transfer RNA-dependent translocation of misactivated amino acids to prevent errors in protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 July 2018

Evidence for dispensable sequences inserted into a nucleotide fold.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

2 July 2018

Distinct kinetic mechanisms of the two classes of Aminoacyl-tRNA synthetases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

tRNA-dependent aminoacyl-adenylate hydrolysis by a nonediting class I aminoacyl-tRNA synthetase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

Hydrolysis of non-cognate aminoacyl-adenylates by a class II aminoacyl-tRNA synthetase lacking an editing domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

Transfer RNA modulates the editing mechanism used by class II prolyl-tRNA synthetase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

An aminoacyl-tRNA synthetase with a defunct editing site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

Rational design to block amino acid editing of a tRNA synthetase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

Molecular dissection of a critical specificity determinant within the amino acid editing domain of leucyl-tRNA synthetase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

Groups on the side chain of T252 in Escherichia coli leucyl-tRNA synthetase are important for discrimination of amino acids and cell viability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

An idiosyncratic serine ordering loop in methanogen seryl-tRNA synthetases guides substrates through seryl-tRNASer formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

Achieving error-free translation; the mechanism of proofreading of threonyl-tRNA synthetase at atomic resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408192

23 September 2018

Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.372151

21 January 2018

CP1 domain in Escherichia coli leucyl-tRNA synthetase is crucial for its editing function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A viable amino acid editing activity in the leucyl-tRNA synthetase CP1-splicing domain is not required in the yeast mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Deacylation by Isoleucyl Transfer Ribonucleic Acid Synthetase of Isoleucine-specific Transfer Ribonucleic Acid Aminoacylated with Valine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exonuclease proofreading by human mitochondrial DNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoacylation error correction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

tRNA-independent pretransfer editing by class I leucyl-tRNA synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new paradigm for DNA polymerase specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22648413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.372151

1 reference

Europe PubMed Central

12 August 2017

release_itlrl6b6ynhxljkiajmfvem24q

1 reference

https://api.fatcat.wiki/v0/release/itlrl6b6ynhxljkiajmfvem24q

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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