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Activation of STIM1-Orai1 involves an intramolecular switching mechanism.
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Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
title
Activation of STIM1-Orai1 involves an intramolecular switching mechanism
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author
Marek Korzeniowski
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3408607
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Tamas Balla
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4
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Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
author name string
Isabel Martín Manjarrés
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2
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Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
Peter Varnai
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3
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PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
publication date
16 November 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
published in
Science Signaling
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
volume
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
issue
148
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
page(s)
ra82
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Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
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STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels
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Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant
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STIM and Orai: dynamic intermembrane coupling to control cellular calcium signals.
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A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels
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PubMed Central
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STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
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A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels
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SOAR and the polybasic STIM1 domains gate and regulate Orai channels
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Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions.
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Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry
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2 October 2017
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
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Hair loss and defective T- and B-cell function in mice lacking ORAI1
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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
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STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle
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Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.
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Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.
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STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels
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2 October 2017
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
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2 October 2017
STIM1, an essential and conserved component of store-operated Ca2+ channel function
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2 October 2017
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PubMed
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2 October 2017
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores
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2 October 2017
Substrate and pseudosubstrate interactions with protein kinases: determinants of specificity
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2 October 2017
A model for receptor-regulated calcium entry
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2 October 2017
Depletion of intracellular calcium stores activates a calcium current in mast cells
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Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1126/SCISIGNAL.2001122
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PMC publication ID
3408607
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
PubMed publication ID
21081754
1 reference
stated in
Europe PubMed Central
PMC publication ID
3408607
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21081754%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 January 2020
ResearchGate publication ID
47809246
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