(Q36129732)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

review article

1 reference

title

Positron emission tomography and single-photon emission computed tomography in central nervous system drug development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

positron emission tomography

1 reference

single-photon emission computed tomography

inferred from title

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

David J Brooks

series ordinal

1

1 reference

12 August 2017

1 April 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

page(s)

226-236

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

11 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Higher atrophy rate of entorhinal cortex than hippocampus in AD.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Amyloid inhibitors and Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Slowing Parkinson's disease progression: recent dopamine agonist trials

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Detection of response to COMT inhibition in FDOPA PET in advanced Parkinson's disease requires prolonged imaging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Continuous dopamine-receptor stimulation in early Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Huntington's disease progression. PET and clinical observations.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: in vivo studies with positron emission tomography

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

2 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

2 October 2017

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Clinical and neuroimaging features of familial Alzheimer's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Clinical and [18F] dopa PET findings in early Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Clinico-neuropathological correlation of Alzheimer's disease in a community-based case series

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

The time course of binding to striatal dopamine D2 receptors by the neuroleptic ziprasidone (CP-88,059-01) determined by positron emission tomography

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Chromosome 14 linked familial Alzheimer's disease. A clinico-pathological study of a single pedigree.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Longitudinal study of the early neuropsychological and cerebral metabolic changes in dementia of the Alzheimer type.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Kinetic modeling of receptor-ligand binding applied to positron emission tomographic studies with neuroleptic tracers

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Simplified reference tissue model for PET receptor studies.

2 July 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Spectral analysis of dynamic PET studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Statistical parametric maps in functional imaging: A general linear approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Regional cerebral glucose metabolism in monozygotic twins discordant for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

A comparison of (18)F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Idiopathic hyposmia as a preclinical sign of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Comparison with Parkinson's disease and controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Novel stilbenes as probes for amyloid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

In-vivo measurement of activated microglia in dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Regulation of striatal aromatic L-amino acid decarboxylase: effects of blockade or activation of dopamine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Chronic L-dopa administration decreases striatal accumulation of dopamine from exogenous L-dopa in rats with intact nigrostriatal projections

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

The effects of chronic levodopa treatment on pre- and postsynaptic markers of dopaminergic function in striatum of parkinsonian monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

[11C]raclopride-PET studies of the Huntington's disease rate of progression: relevance of the trinucleotide repeat length

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

[11C]raclopride and positron emission tomography in previously untreated patients with Parkinson's disease: Influence of L-dopa and lisuride therapy on striatal dopamine D2-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Endogenous dopamine release after pharmacological challenges in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Focal cortical release of endogenous opioids during reading-induced seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Effect of apomorphine on the relationship between local cerebral glucose utilization and local cerebral blood flow (with an appendix on its statistical analysis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

The effect of apomorphine and buspirone on regional cerebral blood flow during the performance of a cognitive task-measuring neuromodulatory effects of psychotropic drugs in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

5-HT(2C) receptor activation by m-chlorophenylpiperazine detected in humans with fMRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Dose dependent occupancy of central dopamine D2 receptors by the novel neuroleptic CP-88,059-01: a study using positron emission tomography and 11C-raclopride

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Evaluating early dementia with and without assessment of regional cerebral metabolism by PET: a comparison of predicted costs and benefits.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Mild cognitive impairment: transition between aging and Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

[11C](R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's encephalitis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Dopaminergic function in familial Parkinson's disease: A clinical and18F-dopa positron emission tomography study

21 October 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease

21 January 2018

2 references

https://api.crossref.org/works/10.1602%2FNEURORX.2.2.226

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1064988

Genetics of Alzheimer's disease

21 October 2018

1 reference

12 December 2020

Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa. Parkinson Study Group

1 reference

12 December 2020

Modulation of [3H]mazindol binding sites in rat striatum by dopaminergic agents

1 reference

12 December 2020

Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat

1 reference

12 December 2020

Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327

1 reference

12 December 2020

1 reference

12 December 2020

The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity

1 reference

12 December 2020

Identifiers

DOI

10.1602/NEURORX.2.2.226

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897947%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

15897947

1 reference