(Q36134856)

12 August 2017

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title

Mammalian defensins in the antimicrobial immune response (English)

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12 August 2017

Michael E Selsted

1

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PubMed ID

15908936

12 August 2017

Andre J Ouellette

series ordinal

2

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PubMed ID

15908936

12 August 2017

language of work or name

English

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publication date

1 June 2005

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12 August 2017

7

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inferred from page(s)

published in

Nature Immunology

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12 August 2017

6

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12 August 2017

551-557

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12 August 2017

6

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Phylogenetic perspectives in innate immunity

12 August 2017

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7 January 2021

Innate immune recognition

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7 January 2021

Antimicrobial peptides of multicellular organisms

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7 January 2021

Antimicrobial proteins and peptides: anti-infective molecules of mammalian leukocytes

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7 January 2021

Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense.

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7 January 2021

Cathelicidins, multifunctional peptides of the innate immunity

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7 January 2021

Defensins: antimicrobial peptides of innate immunity

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7 January 2021

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7 January 2021

[beta]-defensins in lung host defense

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7 January 2021

Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

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7 January 2021

Duplication and selection in the evolution of primate beta-defensin genes

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7 January 2021

Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence

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7 January 2021

Evidence of positively selected sites in mammalian alpha-defensins.

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7 January 2021

A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins

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7 January 2021

Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides

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7 January 2021

Evolution of primate theta-defensins: a serpentine path to a sweet tooth

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7 January 2021

Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.

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7 January 2021

Antimicrobial specificity of leukocyte lysosomal cationic proteins.

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7 January 2021

α-Defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors

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7 January 2021

Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production.

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7 January 2021

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

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7 January 2021

Paneth cell trypsin is the processing enzyme for human defensin-5.

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7 January 2021

RK-2: a novel rabbit kidney defensin and its implications for renal host defense

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7 January 2021

Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes

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7 January 2021

From pro defensins to defensins: synthesis and characterization of human neutrophil pro alpha-defensin-1 and its mature domain

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7 January 2021

Antibacterial activities and conformations of synthetic alpha-defensin HNP-1 and analogs with one, two and three disulfide bridges

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7 January 2021

Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4

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7 January 2021

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

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7 January 2021

Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA.

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7 January 2021

Endotoxin upregulates expression of an antimicrobial peptide gene in mammalian airway epithelial cells

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7 January 2021

Discovery of five conserved beta -defensin gene clusters using a computational search strategy

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7 January 2021

Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis

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7 January 2021

An epididymis-specific beta-defensin is important for the initiation of sperm maturation

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7 January 2021

ESP13.2, a member of the beta-defensin family, is a macaque sperm surface-coating protein involved in the capacitation process

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7 January 2021

hBD-1: a novel beta-defensin from human plasma

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7 January 2021

Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

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7 January 2021

A peptide antibiotic from human skin

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7 January 2021

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

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7 January 2021

Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins

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7 January 2021

Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity

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7 January 2021

Increased concentrations of human beta-defensins in plasma and bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis

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7 January 2021

Increased Bronchoalveolar Lavage Human ??-Defensin Type 2 in Bronchiolitis Obliterans Syndrome after Lung Transplantation

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7 January 2021

Endogenous antimicrobial peptides and skin infections in atopic dermatitis

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7 January 2021

Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes.

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7 January 2021

Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel

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7 January 2021

Degranulation of paneth cells via toll-like receptor 9.

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7 January 2021

Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells

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7 January 2021

Differential expression of alpha- and beta-defensins in human peripheral blood.

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7 January 2021

Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid

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7 January 2021

Production of beta-defensins by human airway epithelia

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7 January 2021

Modulation of human beta-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine production

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7 January 2021

By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide

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7 January 2021

Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

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7 January 2021

IL-22 increases the innate immunity of tissues

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7 January 2021

Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2.

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7 January 2021

Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2.

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7 January 2021

Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells

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7 January 2021

Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C)

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7 January 2021

Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo

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7 January 2021

Microbial DNA induces a host defense reaction of human respiratory epithelial cells

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7 January 2021

Protease-activated receptor signaling increases epithelial antimicrobial peptide expression

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7 January 2021

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

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7 January 2021

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

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7 January 2021

beta-Defensin 1 contributes to pulmonary innate immunity in mice

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7 January 2021

Characterization of the mouse beta defensin 1, Defb1, mutant mouse model.

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7 January 2021

Regulation of Salmonella typhimurium virulence gene expression by cationic antimicrobial peptides.

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7 January 2021

Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity

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7 January 2021

Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations

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7 January 2021

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity

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7 January 2021

A study of host defence peptide beta-defensin 3 in primates

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7 January 2021

Salivary histatin 5 and human neutrophil defensin 1 kill Candida albicans via shared pathways.

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7 January 2021

The Cellular Target of Histatin 5 onCandida albicansIs the Energized Mitochondrion

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7 January 2021

Mammalian defensins: structures and mechanism of antibiotic activity.

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7 January 2021

An enzyme immunoassay for human defensins

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7 January 2021

Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes

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7 January 2021

Differential Scanning Microcalorimetry Indicates That Human Defensin, HNP-2, Interacts Specifically with Biomembrane Mimetic Systems†,‡

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7 January 2021

Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores

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7 January 2021

Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins

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7 January 2021

Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes

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7 January 2021

The cyclic antimicrobial peptide RTD-1 induces stabilized lipid-peptide domains more efficiently than its open-chain analogue

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7 January 2021

Two states of cyclic antimicrobial peptide RTD-1 in lipid bilayers.

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7 January 2021

Solid-state NMR investigation of the selective perturbation of lipid bilayers by the cyclic antimicrobial peptide RTD-1.

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7 January 2021

The θ-Defensin, Retrocyclin, Inhibits HIV-1 Entry

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7 January 2021

Retrocyclin, an Antiretroviral θ-Defensin, Is a Lectin

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7 January 2021

Monocyte-chemotactic activity of defensins from human neutrophils

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7 January 2021

Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils

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7 January 2021

Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

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7 January 2021

Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction

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7 January 2021

Mammalian defensins in immunity: more than just microbicidal

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7 January 2021

Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway

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7 January 2021

Defensins are mitogenic for epithelial cells and fibroblasts

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7 January 2021

Regulation of neovascularization by human neutrophil peptides (alpha-defensins): a link between inflammation and angiogenesis

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7 January 2021

Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro

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7 January 2021

Identifiers

DOI

10.1038/NI1206

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12 August 2017

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PubMed ID

15908936