(Q36136731)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

review article

1 reference

title

Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

positron emission tomography

12 January 2020

main subject

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Philip H Elsinga

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

N Harry Hendrikse

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Aren van Waarde

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Willem Vaalburg

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

publication date

1 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

Molecular Imaging and Biology

12 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

37-44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

The blood-brain barrier. Transport across the cerebral endothelium

12 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11307-005-0951-X

Affinities at the verapamil binding site of MDR1-encoded P-glycoprotein: drugs and analogs, stereoisomers and metabolites

21 January 2018

1 reference

12 December 2020

Synthesis, binding properties, and 18F labeling of fluorocarazolol, a high-affinity beta-adrenergic receptor antagonist

1 reference

12 December 2020

Metabolism of carvedilol in dogs, rats, and mice

1 reference

12 December 2020

(S,S)- and (S,R)-1'-[18F]fluorocarazolol, ligands for the visualization of pulmonary beta-adrenergic receptors with PET.

1 reference

12 December 2020

Preparation and in vivo binding of [11C]carazolol, a radiotracer for the beta-adrenergic receptor

1 reference

12 December 2020

How does P-glycoprotein recognize its substrates?

1 reference

12 December 2020

Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein

1 reference

12 December 2020

Quantitative assessment of P-glycoprotein function in the rat blood-brain barrier by distribution volume of [11C]verapamil measured with PET.

1 reference

12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

1 reference

12 December 2020

Carbon-11-labeled daunorubicin and verapamil for probing P-glycoprotein in tumors with PET.

1 reference

12 December 2020

Copper bis(diphosphine) complexes: radiopharmaceuticals for the detection of multi-drug resistance in tumours by PET.

1 reference

12 December 2020

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1 reference

12 December 2020

The physiological function of drug-transporting P-glycoproteins

1 reference

12 December 2020

Reversal of chloroquine resistance in Plasmodium falciparum by verapamil

1 reference

12 December 2020

P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

1 reference

12 December 2020

Metabolism of carvedilol in man

1 reference

12 December 2020

Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia

1 reference

12 December 2020

Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats

1 reference

12 December 2020

The interaction of some centrally active drugs with the blood-brain barrier and circumventricular organs

1 reference

12 December 2020

What is the blood-brain barrier? A molecular perspective. Cerebral vascular biology.

1 reference

12 December 2020

Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP.

1 reference

12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

12 December 2020

The functional role of P-glycoprotein in the blood-brain barrier

1 reference

12 December 2020

Reversal of multidrug resistance by lipophilic drugs.

1 reference

12 December 2020

Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.

1 reference

12 December 2020

Structural characteristics of compounds that modulate P-glycoprotein-associated multidrug resistance

1 reference

12 December 2020

Chronic reserpine administration selectively up-regulates beta 1- and alpha 1b-adrenergic receptors in rat brain: an autoradiographic study

1 reference

12 December 2020

Relationship between lipophilicity and brain extraction of C-11-labeled radiopharmaceuticals.

1 reference

12 December 2020

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

1 reference

12 December 2020

Biodistribution, radiation dose estimates, and in vivo Pgp modulation studies of 18F-paclitaxel in nonhuman primates

1 reference

12 December 2020

Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy

1 reference

12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

12 December 2020

Validation of S-1'-[18F]fluorocarazolol for in vivo imaging and quantification of cerebral beta-adrenoceptors

1 reference

12 December 2020

Increase in doxorubicin cytotoxicity by carvedilol inhibition of P-glycoprotein activity

1 reference

12 December 2020

The physiology of the blood-brain barrier.

1 reference

12 December 2020

The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system

1 reference

12 December 2020

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

12 December 2020

Safety and efficacy of the multidrug resistance inhibitor Incel (biricodar; VX-710) in combination with paclitaxel for advanced breast cancer refractory to paclitaxel

1 reference

12 December 2020

Enhanced cerebral uptake of receptor ligands by modulation of P-glycoprotein function in the blood-brain barrier.

1 reference

12 December 2020

P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries

1 reference

12 December 2020

Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).

1 reference

12 December 2020

Evaluation of 11C-colchicine for PET imaging of multiple drug resistance.

1 reference

12 December 2020

Characterization of a rat retinal endothelial cell culture and the expression of P-glycoprotein in brain and retinal endothelium in vitro

1 reference

12 December 2020

Evaluation of carbon-14-colchicine biodistribution with whole-body quantitative autoradiography in colchicine-sensitive and -resistant xenografts

1 reference

12 December 2020

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

1 reference

12 December 2020

Influence of P-glycoprotein on brain uptake of [18F]MPPF in rats

1 reference

12 December 2020

A new in vivo method to study P-glycoprotein transport in tumors and the blood-brain barrier

1 reference

12 December 2020

Carazolol, an extremely potent β-adrenergic blocker: Binding to β-receptors in brain membranes

1 reference

12 December 2020

Genetic polymorphism in MDR-1: a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors.

1 reference

12 December 2020

Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.

1 reference

12 December 2020

Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer

1 reference

12 December 2020

Resistance to anthrapyrazoles and anthracyclines in multidrug-resistant P388 murine leukemia cells: reversal by calcium blockers and calmodulin antagonists.

1 reference

12 December 2020

Transporting therapeutics across the blood-brain barrier

1 reference

12 December 2020

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

1 reference

12 December 2020

Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study

1 reference

12 December 2020

Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery

1 reference

12 December 2020

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

1 reference

12 December 2020

Functional involvement of P-glycoprotein in blood-brain barrier

1 reference

12 December 2020

Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.

1 reference

12 December 2020

The blood-brain barrier

1 reference

12 December 2020

Interaction of drugs with P-glycoprotein in brain capillaries

1 reference

12 December 2020

Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

1 reference

12 December 2020

Synthesis and biodistribution of a Lipophilic 64Cu-labeled monocationic Copper(II) complex.

1 reference

12 December 2020

Specialized localization of P-glycoprotein recognized by MRK 16 monoclonal antibody in endothelial cells of the brain and the spinal cord.

1 reference

12 December 2020

Octanol-water partition: searching for predictive models

1 reference

12 December 2020

The blood-brain barrier and oncology: new insights into function and modulation

1 reference

12 December 2020

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein

1 reference

12 December 2020

Imaging beta-adrenoceptors in the human brain with (S)-1'-[18F]fluorocarazolol.

1 reference

12 December 2020

The P-glycoprotein efflux pump: how does it transport drugs?

1 reference

12 December 2020

Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain

1 reference

12 December 2020

Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

1 reference

12 December 2020