(Q36137414)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25850654%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

The prostaglandin D₂ receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung (English)

1 reference

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4 March 2020

5

1 reference

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4 March 2020

author name string

E D Tait Wojno

1

1 reference

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4 March 2020

L A Monticelli

2

1 reference

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4 March 2020

S V Tran

3

1 reference

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4 March 2020

T Alenghat

4

1 reference

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4 March 2020

J J Thome

6

1 reference

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4 March 2020

C Willis

7

1 reference

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4 March 2020

A Budelsky

8

1 reference

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4 March 2020

D L Farber

9

1 reference

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4 March 2020

D Artis

10

1 reference

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4 March 2020

language of work or name

1 reference

8 April 2015

1 reference

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4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25850654%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

8

1 reference

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4 March 2020

issue

6

1 reference

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4 March 2020

page(s)

1313-1323

1 reference

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https://scigraph.springernature.com/pub.10.1038/mi.2015.21

4 March 2020

exact match

0 references

cites work

MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion

1 reference

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Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice

2 October 2017

1 reference

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Discontinued drug projects in the respiratory therapeutic area during 2012.

2 October 2017

1 reference

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Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.

2 October 2017

1 reference

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IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Prostaglandin D2 regulates human type 2 innate lymphoid cell chemotaxis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Innate lymphoid cells and allergic inflammation

2 October 2017

1 reference

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Efficacy and safety of AZD1981, a CRTH2 receptor antagonist, in patients with moderate to severe COPD.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

TH2, allergy and group 2 innate lymphoid cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation

2 October 2017

1 reference

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Innate lymphoid cells--a proposal for uniform nomenclature

2 October 2017

1 reference

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Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Innate lymphoid cells: emerging insights in development, lineage relationships, and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

A randomized, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Nuocytes: expanding the innate cell repertoire in type-2 immunity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Innate Th2-type immune responses and the natural helper cell, a newly identified lymphocyte population

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

SPICE: exploration and analysis of post-cytometric complex multivariate datasets

2 October 2017

1 reference

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Interleukin-4-promoted T helper 2 responses enhance Nippostrongylus brasiliensis-induced pulmonary pathology.

2 October 2017

1 reference

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2 October 2017

1 reference

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Animal model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus.

2 October 2017

1 reference

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The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Prostaglandin D2 induces IL-8 and GM-CSF by bronchial epithelial cells in a CRTH2-independent pathway.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Targeting the prostaglandin D2 receptors DP and CRTH2 for treatment of inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

The importance of Th2 cytokines in protective immunity to nematodes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Type 2 innate lymphoid cells drive CD4+ Th2 cell responses

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598246

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

23 September 2018

1 reference

12 December 2020

Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment

1 reference

12 December 2020

Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation

1 reference

12 December 2020

Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459

1 reference

12 December 2020

Safety and efficacy of the prostaglandin D2 receptor antagonist AMG 853 in asthmatic patients

1 reference

12 December 2020

Identifiers

DOI

10.1038/MI.2015.21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25850654%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25850654%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference