(Q36138342)

12 August 2017

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title

Can cell systems biology rescue drug discovery? (English)

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12 August 2017

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Eugene C Butcher

1

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12 August 2017

1 June 2005

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Nature Reviews Drug Discovery

12 August 2017

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12 August 2017

4

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12 August 2017

461-467

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12 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/nrd1754

12 August 2017

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Knockouts model the 100 best-selling drugs--will they model the next 100?

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21 January 2018

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Engineering cellular microenvironments to improve cell-based drug testing

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Systems biology in drug discovery

21 January 2018

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Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties

21 January 2018

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History of modern psychopharmacology: a personal view with an emphasis on antidepressants

21 January 2018

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Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models

21 January 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

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21 January 2018

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Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro

21 January 2018

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An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

21 January 2018

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Realism in drug discovery-could Cassandra be right?

21 January 2018

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An integrative biology approach for analysis of drug action in models of human vascular inflammation

31 March 2020

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Organic chemistry in drug discovery

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD1754

1 reference

12 August 2017

1 reference

PubMed ID

15915152