(Q36138342)

12 August 2017

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title

Can cell systems biology rescue drug discovery? (English)

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12 August 2017

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Eugene C Butcher

1

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12 August 2017

publication date

1 June 2005

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Nature Reviews Drug Discovery

12 August 2017

published in

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12 August 2017

volume

4

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12 August 2017

issue

6

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12 August 2017

page(s)

461-467

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Modern biomedical research: an internally self-consistent universe with little contact with medical reality?

12 August 2017

cites work

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The price of innovation: new estimates of drug development costs

21 January 2018

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Stategic trends in the drug industry

21 January 2018

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Drug research: myths, hype and reality

21 January 2018

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Knockouts model the 100 best-selling drugs--will they model the next 100?

21 January 2018

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21 January 2018

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21 January 2018

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Of mice and not men: differences between mouse and human immunology

21 January 2018

1 reference

21 January 2018

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Engineering cellular microenvironments to improve cell-based drug testing

21 January 2018

1 reference

Systems biology in drug discovery

21 January 2018

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Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties

21 January 2018

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History of modern psychopharmacology: a personal view with an emphasis on antidepressants

21 January 2018

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Rapid structure-activity and selectivity analysis of kinase inhibitors by BioMAP analysis in complex human primary cell-based models

21 January 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

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Advances in high content screening for drug discovery

21 January 2018

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Prediction of clinical drug efficacy by classification of drug-induced genomic expression profiles in vitro

21 January 2018

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An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

21 January 2018

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Realism in drug discovery-could Cassandra be right?

21 January 2018

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An integrative biology approach for analysis of drug action in models of human vascular inflammation

31 March 2020

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Organic chemistry in drug discovery

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD1754

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12 August 2017

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